Research Progress and Development Prospect of Biomedical Plate_Journal of Biomedical Engineering

Authors：

LIXiao ¹ , LIUJing ¹ , WUQiang ¹ , WANGYanjie ¹ , XIAOTao ² , LIULihong ² ,  YUShu ¹

1. Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083, China;
2. Department of Orthopedics, Second Xiangya Hospital, Central South University, Changsha 410011, China;

Corresponding?author：

YUShu, Email: yushu@csu.edu.cn

Keywords：

bone plate; biomedical materials; carbon/carbon composites

DOI：

10.7507/1001-5515.20160192

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Different generations of biomedical materials are analyzed in this paper. The current clinical uses of plates made of metals, polymers or composite materials are evaluated, and nano hydroxyapatite/polylactic acid composites and carbon/carbon composite plates are introduced as emphasis. It is pointed out that the carbon/carbon composites are of great feasibility and advantage as a new generation of biomedical materials, especially in the field of bone plate. Compared to other biomaterials, carbon/carbon composites have a good biocompatibility and mechanical compatibility because they have similar elastic modulus, porosity and density to that of human bones. With the development of the technology in knitting and material preparation, carbon/carbon composite plates have a good application prospect.

Citation： LIXiao, LIUJing, WUQiang, WANGYanjie, XIAOTao, LIULihong, YUShu. Research Progress and Development Prospect of Biomedical Plate. Journal of Biomedical Engineering, 2016, 33(6): 1214-1219. doi: 10.7507/1001-5515.20160192 Copy

1.	?李明. 鎖定加壓接骨板治療30例脛骨平臺骨折臨床療效觀察[J].現代診斷與治療,2013(20):4690-4691.
2.	RüEDI T P, SOMMER C. From the classical AO compression plate to the new internal fixator principle[J]. 中華創傷骨科雜志, 2003, 5(3): 212-217.
3.	關薇, 翟偉,劉斌,等.接骨板固有風險淺析[J].中國藥物警戒,2013,10(12):752-754.
4.	劉昌星, 盧通成.消除人工髖關節應力遮擋等問題的理論分析與研究[J].中國組織工程研究,2013,17(39):6875-6880.
5.	賴金平, 魏剛,李秀波,等.低應力遮擋效應接骨板的研究與設計[J].生物骨科材料與臨床研究,2007,4(3):51-52.
6.	BEAUPRE G S, CSONGRADI J J. Refracture risk after plate removal in the forearm[J]. J Orthop Trauma, 1996, 10(2): 87-92.
7.	吳煒, 王立軍,徐蓬,等.犬下頜骨骨折小型接骨板內固定術后應力遮擋作用導致骨密度變化的實驗研究[J].醫學信息,2013,26(4):285-286.
8.	HENCH L L. Bioactive materials: the potential for tissue regeneration[J]. J Biomed Mater Res, 1998, 41(4): 511-518.
9.	RADE K, MARTIN A?U I A?U A, NOVAK S, et al. Feasibility study of SiC-ceramics as a potential material for bone implants[J]. Journal of Materials Science, 2013, 48(15): 5295-5301.
10.	AZEM F A, KISS A, BIRLIK I, et al. The corrosion and bioactivity behavior of SiC doped hydroxyapatite for dental applications[J]. Ceramics International, 2014, 40(10, A): 15881-15887.
11.	VLADESCU A, BIRLIK I, BRAIC V, et al. Enhancement of the mechanical properties of hydroxyapatite by SiC addition[J]. J Mech Behav Biomed Mater, 2014, 40: 362-368.
12.	徐小平, 倪衛東,高仕長,等.新型人工生物活性接骨板治療犬股骨骨折[J].中國組織工程研究,2012,16(21):3838-3842.
13.	楊紅勝, 劉躍輝,張斌,等.可變剛度可降解-DL-聚乳酸泡沫襯墊材料與鈦合金組成接骨板系統治療脛骨骨折[J].中國組織工程研究與臨床康復,2011,15(12):2100-2104.
14.	王展, 張軍,張堃,等.內固定材料修復后踝骨折及其生物力學特性[J].中國組織工程研究,2015,19(44):7182-7187.
15.	董雙鵬, 王成燾,齊寶芬,等.肱骨內植物材料選擇及預緊力影響的參數化研究[J].中國骨與關節外科,2014,7(1):35-39.
16.	杜建, 丁元法,蘇向東,等.醫用鎳鈦形狀記憶合金的表面改性及生物相容性[J].中國組織工程研究,2012,16(25):4686-4691.
17.	徐曉宇, 高琨.生物材料學[M].北京:科學出版社,2016:105-106.
18.	于成, 趙衛生,賈偉.生物醫用復合材料的研究進展[J].玻璃鋼/復合材料,2012(2):78-81.
19.	楊明. 納米羥基磷灰石/聚乳酸可吸收椎間融合器的生物力學研究[D].長沙:中南大學,2009.
20.	許哲武, 張志光.乳酸骨內固定材料在正頜外科的應用及改性研究[J].口腔頜面修復學雜志,2014,15(2):110-113.
21.	呂桂浩, 蔣練,滿城.頜面部骨折手術治療的發展現狀[J].醫學美學美容,2015(3):643.
22.	白曉東, 楊冬梅,鐘應權,等.GRAND FIXTM可吸收骨固定系統在頜骨骨折治療中的應用[J].中國保健營養,2013,33(5):2379.
23.	張建偉, 周昌龍,王永盛,等.可吸收內固定微型板在頜面骨折中的應用[J].口腔醫學,2013,33(5):357-358.
24.	程俊秋, 段可,翁杰,等.多孔納米羥基磷灰石-聚乳酸復合材料的制備及其界面研究[J].化學研究與應用,2001,13(5):518-521.
25.	李敏, 唐元,SHAIKH A B,等.聚乳酸/羥基磷灰石納米復合物對MC3T3-E1細胞增殖活性的影響[J].中國組織工程研究,2014,18(43):6929-6934.
26.	馮志海, 樊楨,孔清,等.熱處理溫度對二維高導熱炭/炭復合材料結構及熱導率的影響[J].新型炭材料,2014,29(5):357-362.
27.	EVANS S L, GREGSON P J. Composite technology in load-bearing orthopaedic implants[J]. Biomaterials, 1998, 19(15): 1329-1342.
28.	WANG Guohui, YU Shu, ZHU Shaihong, et al. Biological properties of carbon/carbon implant composites with unique manufacturing processes[J]. J Mater Sci Mater Med, 2009, 20(12): 2487-2492.
29.	倪聽曄, 李愛軍,鐘萍,等.不同高溫處理工藝對C/C復合材料生物相容性的影響[J].材料工程,2014(6):62-67.
30.	劉京, 肖鵬,于澍,等.炭基復合材料與人骨的力學性能對比分析[J/OL].復合材料學報.(2016-03-11)[2016-07-17].http://www.cnki.net/kcms/detail/11.1801.TB.20160311.1456.002.html.
31.	馬藝林. 醫用C/C復合材料力學性能和體外相容性研究[D].長沙:中南大學,2014.
32.	吳琪琳, 潘鼎.炭材料在醫學領域的應用[J].材料導報,2003,17(8):54-56.
33.	BRANDWOOD A, NOBLE K R, SCHINDHELM K. Phagocytosis of carbon particles by macrophages in vitro[J]. Biomaterials, 1992, 13(9): 646-648.
34.	MUKHERJEE D P, SAHA S. The application of new composite materials for total joint arthroplasty[J]. J Long Term Eff Med Implants, 1993, 3(2): 131-141.
35.	LEWANDOWSKA-SZUMIE? M, KOMENDER J, GóRECKI A, et al. Fixation of carbon fibre-reinforced carbon composite implanted into bone[J]. J Mater Sci Mater Med, 1997, 8(8): 485-488.
36.	PESáKOVá V, KLéZL Z, BALíK K, et al. Biomechanical and biological properties of the implant material carbon-carbon composite covered with pyrolytic carbon[J]. J Mater Sci Mater Med, 2000, 11(12): 793-798.
37.	LEWANDOWSKA-SZUMIE? M, KOMENDER J, CH?OPEK J. Interaction between carbon composites and bone after intrabone implantation[J]. J Biomed Mater Res, 1999, 48(3): 289-296.
38.	陳永強, 戴克戎,方如華,等.混雜復合材料接骨板的實驗研究[J].中華骨科雜志,1995,15(8):529-531.
39.	方如華, 袁旬華,采林春,等.混雜復合材料接骨板的研制[J].醫用生物力學,1993,8(1):1-8.
40.	LI S, ZHENG Z, LIU Q, et al. Collage/apatite coating on 3-dimensional carbon/carbon composite[J]. J Biomed Mater Res, 1998, 40(4): 520-529.
41.	STOCH A, JASTRZEBSKI W, BROZBEK A, et al. FTIR monitoring of the growth of the carbonate containing apatite layers from simulated and natural body fluids[J]. J Mol Struct, 1999, 511: 287-294.
42.	PIETAK A M, REID J W, STOTT M J, et al. Silicon substitution in the calcium phosphate bioceramics[J]. Biomaterials, 2007, 28(28): 4023-4032.
43.	LAI W, GARINO J, DUCHEYNE P. Silicon excretion from bioactive glass implanted in rabbit bone[J]. Biomaterials, 2002, 23(1): 213-217.

1. ?李明. 鎖定加壓接骨板治療30例脛骨平臺骨折臨床療效觀察[J].現代診斷與治療,2013(20):4690-4691.
2. RüEDI T P, SOMMER C. From the classical AO compression plate to the new internal fixator principle[J]. 中華創傷骨科雜志, 2003, 5(3): 212-217.
3. 關薇, 翟偉,劉斌,等.接骨板固有風險淺析[J].中國藥物警戒,2013,10(12):752-754.
4. 劉昌星, 盧通成.消除人工髖關節應力遮擋等問題的理論分析與研究[J].中國組織工程研究,2013,17(39):6875-6880.
5. 賴金平, 魏剛,李秀波,等.低應力遮擋效應接骨板的研究與設計[J].生物骨科材料與臨床研究,2007,4(3):51-52.
6. BEAUPRE G S, CSONGRADI J J. Refracture risk after plate removal in the forearm[J]. J Orthop Trauma, 1996, 10(2): 87-92.
7. 吳煒, 王立軍,徐蓬,等.犬下頜骨骨折小型接骨板內固定術后應力遮擋作用導致骨密度變化的實驗研究[J].醫學信息,2013,26(4):285-286.
8. HENCH L L. Bioactive materials: the potential for tissue regeneration[J]. J Biomed Mater Res, 1998, 41(4): 511-518.
9. RADE K, MARTIN A?U I A?U A, NOVAK S, et al. Feasibility study of SiC-ceramics as a potential material for bone implants[J]. Journal of Materials Science, 2013, 48(15): 5295-5301.
10. AZEM F A, KISS A, BIRLIK I, et al. The corrosion and bioactivity behavior of SiC doped hydroxyapatite for dental applications[J]. Ceramics International, 2014, 40(10, A): 15881-15887.
11. VLADESCU A, BIRLIK I, BRAIC V, et al. Enhancement of the mechanical properties of hydroxyapatite by SiC addition[J]. J Mech Behav Biomed Mater, 2014, 40: 362-368.
12. 徐小平, 倪衛東,高仕長,等.新型人工生物活性接骨板治療犬股骨骨折[J].中國組織工程研究,2012,16(21):3838-3842.
13. 楊紅勝, 劉躍輝,張斌,等.可變剛度可降解-DL-聚乳酸泡沫襯墊材料與鈦合金組成接骨板系統治療脛骨骨折[J].中國組織工程研究與臨床康復,2011,15(12):2100-2104.
14. 王展, 張軍,張堃,等.內固定材料修復后踝骨折及其生物力學特性[J].中國組織工程研究,2015,19(44):7182-7187.
15. 董雙鵬, 王成燾,齊寶芬,等.肱骨內植物材料選擇及預緊力影響的參數化研究[J].中國骨與關節外科,2014,7(1):35-39.
16. 杜建, 丁元法,蘇向東,等.醫用鎳鈦形狀記憶合金的表面改性及生物相容性[J].中國組織工程研究,2012,16(25):4686-4691.
17. 徐曉宇, 高琨.生物材料學[M].北京:科學出版社,2016:105-106.
18. 于成, 趙衛生,賈偉.生物醫用復合材料的研究進展[J].玻璃鋼/復合材料,2012(2):78-81.
19. 楊明. 納米羥基磷灰石/聚乳酸可吸收椎間融合器的生物力學研究[D].長沙:中南大學,2009.
20. 許哲武, 張志光.乳酸骨內固定材料在正頜外科的應用及改性研究[J].口腔頜面修復學雜志,2014,15(2):110-113.
21. 呂桂浩, 蔣練,滿城.頜面部骨折手術治療的發展現狀[J].醫學美學美容,2015(3):643.
22. 白曉東, 楊冬梅,鐘應權,等.GRAND FIXTM可吸收骨固定系統在頜骨骨折治療中的應用[J].中國保健營養,2013,33(5):2379.
23. 張建偉, 周昌龍,王永盛,等.可吸收內固定微型板在頜面骨折中的應用[J].口腔醫學,2013,33(5):357-358.
24. 程俊秋, 段可,翁杰,等.多孔納米羥基磷灰石-聚乳酸復合材料的制備及其界面研究[J].化學研究與應用,2001,13(5):518-521.
25. 李敏, 唐元,SHAIKH A B,等.聚乳酸/羥基磷灰石納米復合物對MC3T3-E1細胞增殖活性的影響[J].中國組織工程研究,2014,18(43):6929-6934.
26. 馮志海, 樊楨,孔清,等.熱處理溫度對二維高導熱炭/炭復合材料結構及熱導率的影響[J].新型炭材料,2014,29(5):357-362.
27. EVANS S L, GREGSON P J. Composite technology in load-bearing orthopaedic implants[J]. Biomaterials, 1998, 19(15): 1329-1342.
28. WANG Guohui, YU Shu, ZHU Shaihong, et al. Biological properties of carbon/carbon implant composites with unique manufacturing processes[J]. J Mater Sci Mater Med, 2009, 20(12): 2487-2492.
29. 倪聽曄, 李愛軍,鐘萍,等.不同高溫處理工藝對C/C復合材料生物相容性的影響[J].材料工程,2014(6):62-67.
30. 劉京, 肖鵬,于澍,等.炭基復合材料與人骨的力學性能對比分析[J/OL].復合材料學報.(2016-03-11)[2016-07-17].http://www.cnki.net/kcms/detail/11.1801.TB.20160311.1456.002.html.
31. 馬藝林. 醫用C/C復合材料力學性能和體外相容性研究[D].長沙:中南大學,2014.
32. 吳琪琳, 潘鼎.炭材料在醫學領域的應用[J].材料導報,2003,17(8):54-56.
33. BRANDWOOD A, NOBLE K R, SCHINDHELM K. Phagocytosis of carbon particles by macrophages in vitro[J]. Biomaterials, 1992, 13(9): 646-648.
34. MUKHERJEE D P, SAHA S. The application of new composite materials for total joint arthroplasty[J]. J Long Term Eff Med Implants, 1993, 3(2): 131-141.
35. LEWANDOWSKA-SZUMIE? M, KOMENDER J, GóRECKI A, et al. Fixation of carbon fibre-reinforced carbon composite implanted into bone[J]. J Mater Sci Mater Med, 1997, 8(8): 485-488.
36. PESáKOVá V, KLéZL Z, BALíK K, et al. Biomechanical and biological properties of the implant material carbon-carbon composite covered with pyrolytic carbon[J]. J Mater Sci Mater Med, 2000, 11(12): 793-798.
37. LEWANDOWSKA-SZUMIE? M, KOMENDER J, CH?OPEK J. Interaction between carbon composites and bone after intrabone implantation[J]. J Biomed Mater Res, 1999, 48(3): 289-296.
38. 陳永強, 戴克戎,方如華,等.混雜復合材料接骨板的實驗研究[J].中華骨科雜志,1995,15(8):529-531.
39. 方如華, 袁旬華,采林春,等.混雜復合材料接骨板的研制[J].醫用生物力學,1993,8(1):1-8.
40. LI S, ZHENG Z, LIU Q, et al. Collage/apatite coating on 3-dimensional carbon/carbon composite[J]. J Biomed Mater Res, 1998, 40(4): 520-529.
41. STOCH A, JASTRZEBSKI W, BROZBEK A, et al. FTIR monitoring of the growth of the carbonate containing apatite layers from simulated and natural body fluids[J]. J Mol Struct, 1999, 511: 287-294.
42. PIETAK A M, REID J W, STOTT M J, et al. Silicon substitution in the calcium phosphate bioceramics[J]. Biomaterials, 2007, 28(28): 4023-4032.
43. LAI W, GARINO J, DUCHEYNE P. Silicon excretion from bioactive glass implanted in rabbit bone[J]. Biomaterials, 2002, 23(1): 213-217.

Previous Article
Advances of Function of Prussian Blue Nano-materials in Cancer Diagnosis and Therapy
Next Article
Advances in Researches on the Relations between miRNA-143/miRNA-145 and Colorectal Cancer

Journal of Biomedical Engineering

Research Progress and Development Prospect of Biomedical Plate

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content