• 1. Department of Epidemiology and Biostatistics, West China School of Public Health; 2. Department of Ultrasound, West China Hospital; 3. National Clinical Trials Agencies, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
FENG Ping, Email: zhangwei19880404@163.com
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目的  應用判別分析探討不同指標對前列腺癌預測診斷中的應用價值。 方法  收集2008年1月-2011年9月經直腸超聲檢查并行經直腸超聲引導下經會陰前列腺穿刺活檢術,具有前列腺特異性抗原(PSA)、超聲圖像特征的941例患者以及其中含有血流阻力指數(RI)指標的200例患者的臨床資料,采用最近距離及極大似然判別分析兩種方法分別擬合患者年齡、血清PSA、經直腸前列腺超聲聲像圖特征以及RI指標預測前列腺癌。 結果  最近距離判別分析顯示RI對前列腺癌的判別無臨床意義。聯合患者年齡、超聲檢查和血清PSA值,判別結果提示超聲、超聲+年齡、年齡+超聲+PSA三種判別的靈敏度逐漸增加。年齡+超聲+PSA聯合指標的靈敏度為88.89%,其錯判率在20.00%以內。 結論  年齡+超聲+PSA聯合指標的極大似然判別分析可提高前列腺癌的診斷預測水平,避免前列腺穿刺給患者帶來的痛苦,并給臨床醫生的臨床診斷提供參考,有較好的應用價值。

Citation: ZHANG Wei,LI Yongzhong,FENG Ping,YUAN Jiaying,GOU Zhongping.. Application of Discriminant Analysis in Exploring the Diagnostic Value of Different Indicators for Prostate Cancer. West China Medical Journal, 2013, 28(4): 563-566. doi: 10.7507/1002-0179.20130179 Copy

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