Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy_West China Medical Journal

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West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

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Keywords：

改良電休克; 異丙酚; 腦電抽搐時間; 動態阻抗; 靜態阻抗

DOI：

10.7507/1002-0179.20130230

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目的　探討改良電休克治療（MECT）中影響腦電抽搐時間的因素。方法　回顧性分析2011年10月－2011年12月經MECT的111例精神障礙患者的臨床資料，利用Pearson相關分析方法進行統計，分析異丙酚用量、性別、設定電量、動態阻抗等因素對腦電抽搐時間的影響。結果　男性異丙酚用量平均值大于女性。女性的年齡、能量設定百分比、靜態阻抗、動態阻抗均大于男性。與抽搐發作時間相關的因素是年齡、設定能量百分比。異丙酚劑量與腦電抽搐時間無相關。以腦電抽搐時間≥25 s為判定標準，男性的反應率高于女性。結論　行MECT時，需考慮患者年齡對發作時間的影響，異丙酚可安全用于MECT中。

Citation： MU Jie,WANG Rurong.. Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy. West China Medical Journal, 2013, 28(5): 746-748. doi: 10.7507/1002-0179.20130230 Copy

1.	張新凱, 翁巍駿, 盧虹, 等. 電抽搐治療精神疾病的發現與發展簡史[ J]. 中華醫史雜志, 2001, 3(4): 213- 216.
2.	馮鵬玖, 蔣宗濱, 黃劍鋒, 等. 不同劑量丙泊酚對電休克治療患者心血管反應和癲癇發作的影響[J]. 廣西醫學, 2007, 28(11): 1769-1771.
3.	Ding Z, White PF. Anesthesia for electroconvulsive therapy[J]. Anesth Analg, 2002, 94(5): 1351-1364.
4.	蘇潔, 陳奮鶯. 丙泊酚和依托咪酯在68例無抽搐電休克治療中的臨床應用[J].福建醫藥雜志, 2011, 33(2): 116-117.
5.	胡巧媚. 無抽搐電休克的麻醉體會[J]. 實用醫技雜志, 2008, 15(32): 4637-4638.
6.	Madhavan S, Nadeem Z. Response predictors in ECT: a discussion about seizure threshold[J]. BJMP, 2011, 4(2): 424.
7.	Eranti SV, Mogg AJ, Pluck GC, et al. Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: a naturalistic comparison study[J]. J Affect Disord, 2009, 113(1-2): 165-171.
8.	Coffey CE, Lucke J, Weiner RD, et al. Seizure threshold in electroconvulsive therapy：I. Initial seizure threshold[J]. Biol Psychiatry, 1995, 37(10): 713-720.
9.	毛洪京, 駱宏, 陳樹林, 等. 導致改良電休克治療發作不良因素分析[J]. 浙江臨床醫學, 2007, 9(5): 683-684.
10.	Rasmussen K. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging[J]. J ECT, 2002, 18(1): 58-59.
11.	Stevens A, Fischer A, Bartels M, et al. Electroconvulsive therapy: a review on indications, methods, risks and medication[J]. Eur Psychiatry, 1996, 11(4): 165-174.
12.	Chung KF. Relationships between seizure duration and seizure threshold and stimulus dosage at electroconvulsive therapy: implications for electroconvulsive therapy practice[J]. Psychiatry Clin Neurosci, 2002, 56(5): 521-526.
13.	van Waarde JA, van der Mast RC. Seizure thresholds in elderly patients treated with electroconvulsive therapy for major depressive disorder: a review[J]. Curr Psychiatry Rev, 2010, 6(3): 184-190.
14.	van Waarde JA, van Oudheusden LJ, Verwey B, et al. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study[J]. Eur Arch Psychiatry Clinc Neurosci, 2013, 263(2): 167-175.
15.	Shapira B, Lidsky D, Gorfine, M, et a1. Electroconvulsive therapy and resistant depression:clinical implications of seizure threshold[J]. J Clin Psychiatry, 1996, 57(1): 32-38．.

1. 　張新凱, 翁巍駿, 盧虹, 等. 電抽搐治療精神疾病的發現與發展簡史[ J]. 中華醫史雜志, 2001, 3(4): 213- 216.
2. 　馮鵬玖, 蔣宗濱, 黃劍鋒, 等. 不同劑量丙泊酚對電休克治療患者心血管反應和癲癇發作的影響[J]. 廣西醫學, 2007, 28(11): 1769-1771.
3. 　Ding Z, White PF. Anesthesia for electroconvulsive therapy[J]. Anesth Analg, 2002, 94(5): 1351-1364.
4. 　蘇潔, 陳奮鶯. 丙泊酚和依托咪酯在68例無抽搐電休克治療中的臨床應用[J].福建醫藥雜志, 2011, 33(2): 116-117.
5. 　胡巧媚. 無抽搐電休克的麻醉體會[J]. 實用醫技雜志, 2008, 15(32): 4637-4638.
6. 　Madhavan S, Nadeem Z. Response predictors in ECT: a discussion about seizure threshold[J]. BJMP, 2011, 4(2): 424.
7. 　Eranti SV, Mogg AJ, Pluck GC, et al. Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: a naturalistic comparison study[J]. J Affect Disord, 2009, 113(1-2): 165-171.
8. 　Coffey CE, Lucke J, Weiner RD, et al. Seizure threshold in electroconvulsive therapy：I. Initial seizure threshold[J]. Biol Psychiatry, 1995, 37(10): 713-720.
9. 　毛洪京, 駱宏, 陳樹林, 等. 導致改良電休克治療發作不良因素分析[J]. 浙江臨床醫學, 2007, 9(5): 683-684.
10. 　Rasmussen K. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging[J]. J ECT, 2002, 18(1): 58-59.
11. 　Stevens A, Fischer A, Bartels M, et al. Electroconvulsive therapy: a review on indications, methods, risks and medication[J]. Eur Psychiatry, 1996, 11(4): 165-174.
12. 　Chung KF. Relationships between seizure duration and seizure threshold and stimulus dosage at electroconvulsive therapy: implications for electroconvulsive therapy practice[J]. Psychiatry Clin Neurosci, 2002, 56(5): 521-526.
13. 　van Waarde JA, van der Mast RC. Seizure thresholds in elderly patients treated with electroconvulsive therapy for major depressive disorder: a review[J]. Curr Psychiatry Rev, 2010, 6(3): 184-190.
14. 　van Waarde JA, van Oudheusden LJ, Verwey B, et al. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study[J]. Eur Arch Psychiatry Clinc Neurosci, 2013, 263(2): 167-175.
15. 　Shapira B, Lidsky D, Gorfine, M, et a1. Electroconvulsive therapy and resistant depression:clinical implications of seizure threshold[J]. J Clin Psychiatry, 1996, 57(1): 32-38．.

West China Medical Journal

Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy

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