Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease_West China Medical Journal

Authors：

ZUO Wen , CHEN Zhubi , WANG Jianqiu , LUO Ying , HAN Wenbin , HE Jun.

Department of Radiology, the First People’s Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;

Corresponding?author：

Keywords：

冠狀動脈狹窄; 冠狀動脈粥樣硬化斑塊; 體層攝影術，X線計算機

DOI：

10.7507/1002-0179.20130493

Video：

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目的　應用128層螺旋CT冠狀動脈成像，探討冠狀動脈不同成分斑塊與狹窄程度的診斷價值。方法　對2010年3月－2012年10月150例臨床擬診冠心病及確診冠心病患者的128層螺旋CT冠狀動脈成像檢查，冠狀動脈影像表現由兩位心血管CT診斷醫師獨立判斷冠狀動脈斑塊成分及測量冠狀動脈狹窄程度。應用Circulation血管分析軟件，分析冠狀動脈斑塊成分與狹窄程度之間的相關性。結果　150例患者中，共發現319處斑塊，其中軟斑塊104處，纖維、混合斑塊103處，鈣化斑塊112處。冠狀動脈輕度狹窄114處中，鈣化斑塊86處（75.4%）；冠狀動脈中度狹窄113處中，纖維、混合斑塊75處（66.3%）；冠狀動脈重度狹窄92處中，軟斑塊68處（73.9%）。結論　128層螺旋CT冠狀動脈成像能夠有效檢測患者冠狀動脈斑塊的成分及準確判斷冠狀動脈狹窄程度。

Citation： ZUO Wen,CHEN Zhubi,WANG Jianqiu,LUO Ying,HAN Wenbin,HE Jun.. Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease. West China Medical Journal, 2013, 28(10): 1564-1566. doi: 10.7507/1002-0179.20130493 Copy

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1. 　Pugliese F, Moler NRA, Runza G, et al. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris[J]. Eur Radiol, 2006, 16(3): 575．.
2. 　Johnson TR, Nikolaou K, Busch S, et al. Diagnostic accuracy of dual-source computed tomography in the diagnosis of coronary artery disease[J]. Invest Radiol, 2007, 42(10): 684-691．.
3. 　張惠茅, 王睿, 胡博奇. 多排螺旋CT對冠狀動脈斑塊的診斷價值[J]. 中國實驗診斷學, 2010, 14(7): 1158-1159.
4. 　Scbroeder S, Kopp AF, Bnambaeb A, et al. Noninvasive detection and evaluation of athemscleratic coronary plaques with muhilice computed tomography[J]. J Am Coil Cardiol, 2001, 37(5): 1430-1435.
5. 　李玉林,唐建武.病理學[M]. 6版. 北京: 人民衛生出版社, 2003: 132-134.
6. 　李甘地, 來茂德．病理學(七年制)[M]. 北京: 人民衛生出版社, 2001: 159-161．.
7. 　Tanaka A, Shimada K, Sano T, et al. Multiple plaque ruptureand C-reactive protein in acute myocardial infarction[J]. J Am Coil Cardiol, 2005, 45(10): 1594-1599．.
8. 　Fujii K, Mintz GS, Kobayashi Y, et al. Vascular remodeling and plaque composition between focal and difuse coronary lesions assessed by in travascular ultrasound[J]. Am J Cardiol, 2004, 94(8): 1067-1070.
9. 　毛定飆, 滑炎卿, 王鳴鵬, 等. 心率及重建相位窗對多層螺旋CT冠狀動脈造影圖像質量的影響[J]. 中華放射學雜志, 2004, 38(5): 521-524．.
10. 　Kaski JC. Athelomatous plaque location and arterial remodelling[J]. Eur Heart J, 2003, 24(4): 291-293.
11. 　靳海斌, 王旭開, 楊成明, 等. 64層CT冠狀動脈成像與冠狀動脈造影的影像對比研究[J]. 重慶醫學, 2008, 37(6): 597-599．.
12. 　黃賢勝, 曹振東, 李俊玫, 等. 64層螺旋CT對冠狀動脈粥樣硬化斑塊的診斷價值[J]. 放射學實踐, 2009, 24(5): 487-490．.
13. 　肖喜剛, 韓雪, 王雪紅, 等. 多層螺旋CT冠狀動脈成像在冠心病中的臨床應用[J]. 中華放射學雜志, 2004, 38(9): 957-961．.

West China Medical Journal

Correlation between Coronary Plaque Composition and Degree of Stenosis by 128-slice Spiral Computed Tomography Coronary Angiography in Patients with Coronary Heart Disease

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