麝香保心丸治療老年慢性充血性心力衰竭的療效觀察_West China Medical Journal

Authors：

 牛嬋娟 , 劉平

秦皇島市北戴河醫院內科（河北秦皇島，066100）;

Corresponding?author：

Keywords：

麝香保心丸; 慢性充血性心力衰竭; C-反應蛋白; 老年患者

DOI：

10.7507/1002-0179.20140092

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目的研究麝香保心丸治療老年慢性心力衰竭的療效觀察及對C-反應蛋白（CRP）的影響。方法將2010年1月－2012年1月收治的62例患者隨機分為治療組及對照組，每組31例，兩組均給予一般治療及基礎藥物治療，治療組加用麝香保心丸。治療30 d后檢測心搏出量（SV）、左心室射血分數（LVEF）、左心室收縮末期容積指數（LVESVI）、左心室舒張末期容積指數（LVEDVI）及CRP，兩組進行對照比較。結果兩組患者各項指標較治療前均顯著改善，且治療組大部分指標的改變顯著高于對照組。結論麝香保心丸能降低心肌耗氧量，增強心肌收縮力，降低血清CRP濃度，減輕炎癥反應，顯著改善心衰癥狀。

Citation： 牛嬋娟, 劉平. 麝香保心丸治療老年慢性充血性心力衰竭的療效觀察. West China Medical Journal, 2014, 29(2): 303-304. doi: 10.7507/1002-0179.20140092 Copy

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1. 王麗潔,羅心平,王涌,等.冠心病穩定性心絞痛患者長期應用麝香保心丸的臨床耐受性與安全性評價[J].中國中西醫結合雜志,2008,28(5):399-401.
2. 孫菁,周進祝.內科學[M].7版.北京:科學出版社,2003:298-299.
3. Rapezzi C,Biagini E,Branzi A.Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes:the task force for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes of the European Society of Cardiology[J].Eur Heart J,2007,28(13):1598-1660.
4. Lloyd-Jones DM,Liu K,Tian L,et al.Narrative review:assessment of C-reactive protein in risk prediction for cardiovascular disease[J].Ann Intern Med,2006,145(1):35-42.
5. Arima H,Kubo M,Yonemoto K,et al.High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese:the Hisayama study[J].Arterioscler Thromb Vasc Biol,2008,28(7):1385-1391.
6. Tao L,Gao E,Jiao X,et al.Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress[J].Circulation,2007,115(11):1408-1416.
7. 車賢達,錢琳艷,高瑞蘭.麝香保心丸預防冠心病PCI術后再狹窄的臨床療效觀察[J].中華中醫藥學刊,2008,26(4):765-766.
8. 梁鐵軍,趙小茜,王愛武,等.麝香保心丸治療心律失常238例療效分析[J].山東醫藥,2004,44(23):24-25.

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麝香保心丸治療老年慢性充血性心力衰竭的療效觀察

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