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Authors：

 RENYan-ling ,  FENGHong-ping

Department of Infectious Diseases, Dongfeng Affiliated Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P. R. China;

Corresponding?author：

FENGHong-ping, Email: f1h2p3@sohu.com

Keywords：

Hepatitis B; Liver cirrhosis; Antiviral; Strengthening intervention; Treatment compliance

DOI：

10.7507/1002-0179.20140096

Video：

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Objective To investigate the influence of strengthening intervention on antiviral treatment compliance for cirrhosis patients following chronic hepatitis B. Methods One hundred patients with cirrhosis following chronic hepatitis B undergoing antiviral treatment between January 2007 and January 2009 were randomly divided into intervention group and control group with 50 patients in each group.Patients in the control group received routine care.For patients in the intervention group,besides routine care,strengthening education on the disease,medication guide,and weekly telephone follow-up after discharge were also added.On the time points of 6,12,18,24,30,36 months after patients were discharged,we followed them up with self-designed questionnaire,and compared the two groups of patients on the rates of fully complying with doctors,not fully complying with doctors and completely not complying with doctors.And the reasons were also analyzed. Results Eighteen months after being discharged,the two groups had no significant difference in the rate of complying with doctors (P>0.05),while the difference was significant 24,30,36 months after leaving the hospital (P<0.05).The reasons were not following the doctors were mainly high cost and unsatisfying treatment effect.In the control group,the reasons also included lack of knowledge about the disease and lack of guidance and supervision. Conclusion Through strengthening nursing intervention,patients'treatment compliance can be improved significantly.

Citation： RENYan-ling, FENGHong-ping. .. West China Medical Journal, 2014, 29(2): 311-314. doi: 10.7507/1002-0179.20140096 Copy

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12.	楊梅,楊彥佳,王震玲,等.四川地區慢性乙型肝炎患者對抗病毒治療的依從性影響因素分析[J].華西醫學,2013,28(10):1555-1558.
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1. 盧平宣.慢性乙型肝炎抗病毒治療的現狀和進展[J].內科,2008,3(2):246-248.
2. 陸惠潔,卜桂珍.系統健康教育對門診慢性乙型肝炎患者抗病毒治療依從性的影響[J].護理實踐與研究,2010,7(6):117-119.
3. Lok ASF,Mc Mahon BJ.Chronic hepatitis B[J].Hepatology,2007,45(2):507-539.
4. 沈愛宗,陳飛虎,張善堂,等.美國慢性疾病藥物治療的依從性研究[J].國外醫學·社會醫學分冊,2004,21(4):155-159.
5. 楊麗翠,孫玉梅,李春梅,等.慢性乙型肝炎患者依從性現狀的調查分析[J].解放軍護理雜志,2009,26(9):19-22.
6. 中華醫學會肝病學分會、感染病學分會.慢性乙型肝炎防治指南[J].中華肝臟病雜志,2005,13(12):881-891.
7. 戴曉陽.護理心理學[M].北京:人民衛生出版社,1998:128-130.
8. 鄭洋,范蕓.慢性乙型肝炎患者口服核苷酸類似物抗病毒治療依從性調查與分析[J].內科理論與實踐,2013,8(4):289-290.
9. 于明震.慢性乙型肝炎復發誘因分析及護理[J].現代醫藥衛生,2001,17(2):127.
10. 段海葉,李艷芳.導致乙肝病人抗病毒治療不遵醫行為的原因調查分析[J].中國實用神經疾病雜志,2011,14(10):55-56.
11. 董南,何波,莊輝.慢性乙型肝炎患者對疾病和抗病毒治療的認知程度調查[J].肝臟,2009,14(1):8-10.
12. 楊梅,楊彥佳,王震玲,等.四川地區慢性乙型肝炎患者對抗病毒治療的依從性影響因素分析[J].華西醫學,2013,28(10):1555-1558.
13. 萬彬,羅東霞.慢性乙型肝炎患者健康教育需求調查分析[J].華西醫學,2009,24(5):1290-1292.
14. 沈娟,錢湘云.自我管理干預在提高慢性乙型肝炎病人治療依從性中的應用[J].護理研究,2012,26(7):1963-1964.
15. 李延云.電話隨訪對慢性乙型肝炎患者抗病毒治療依從性的影響[J].齊魯護理雜志,2012,18(22):93-94.
16. 毛鑫群,仲冬梅,蔣艷.乙型肝炎后肝硬化患者服用抗病毒藥物治療依從性的調查[J].解放軍護理雜志,2012,29(5A):26-28.

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