Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011_West China Medical Journal

Authors：

HUANGWen-zhi , ZHUANGHong-di , LIShi-yu ,  QIAOFu , WANGYan-tong , YINWei-jia , ZONGZhi-yong , RAOLi

Department of Nosocomial Infection Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

QIAOFu, Email: qiaofu2005@gmail.com

Keywords：

Cross-sectional survey; Antimicrobial agents; Rational drug use

DOI：

10.7507/1002-0179.20140123

Video：

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Objective To investigate and analyze the antibiotic use in Sichuan Province. Methods Antibiotic use of inpatients was investigated in 23 hospitals on the day of June 25, 2011. Results The percentage of antibiotic use was 42.4% in the total 27 144 inpatients, the range of which was between 24.3% and 63.3% for each hospital. And 63.8% of the antibiotic use was for therapeutic purpose, and 72.2% used only one antibiotic drug. A total of 36.9% of the patients receiving antibiotic treatment for therapeutic use sent samples for pathogenic detection. With the increase of the size of the hospital (judged by the number of beds), antimicrobial drug utilization decreased with statistical significance (χ²=411.834, P=0.000). With the improvement of regional economic level (judged by per-capita GDP of each region), the hospital antimicrobial usage decreased with statistical significance (χ²=500.093, P=0.000). The three types of antimicrobial drug most frequently used were other β-lactam antibiotics, penicillin and third generation cephalosporin. Conclusion Antibiotic use is reasonable in Sichuan Province as a whole. However, it is necessary to reduce irrational use of antimicrobial agents continuously, and to strengthen the management of clinical antibiotic usage among inpatients.

Citation： HUANGWen-zhi, ZHUANGHong-di, LIShi-yu, QIAOFu, WANGYan-tong, YINWei-jia, ZONGZhi-yong, RAOLi. Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011. West China Medical Journal, 2014, 29(3): 404-408. doi: 10.7507/1002-0179.20140123 Copy

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2. 四川省統計局. 四川統計年鑒2012[M]. 北京:中國統計出版社, 2012:44.
3. 中華人民共和國國家衛生和計劃生育委員會. 2013年全國抗菌藥物臨床應用專項整治活動方案[EB/OL]. (2013-05-07)[2013-12-01]. http://www.moh.gov.cn/ewebeditor/uploadfile/2013/05/20130509133856278.doc.
4. 吳安華, 李春輝, 文細毛, 等. 2010年中國740所醫院住院患者抗菌藥物日使用率調查[J]. 中國感染控制雜志, 2012, 11(1):7-11.
5. 任南, 文細毛, 吳安華. 全國醫院感染橫斷面調查結果的變化趨勢研究[J]. 中國感染控制雜志, 2007, 6(1):16-18.
6. 張驥, 王翀, 熊鴻燕, 等. 2010年度貴州省108所醫院住院患者橫斷面抗菌藥物使用率調查[J]. 中國感染控制雜志, 2012, 11(6):430-434.
7. 邢紅霞, 張紅鷹, 張建平, 等. 華北地區18所醫院抗菌藥物使用管理調查[J]. 中華醫院感染學雜志, 2003, 13(9):858-860.
8. 劉敬偉. 長沙市醫保住院患者抗菌藥物使用的流行病學研究[D]. 長沙:中南大學, 2011.
9. 陳峰英, 王硯, 徐琪. 住院病人抗菌藥物使用調查結果分析及管理措施[J]. 中國醫藥導報, 2007, 4(26):164-165.
10. 孫麗萍. 長春市某三甲醫院醫院感染現況調查分析[D]. 長春:吉林大學, 2010.
11. 徐潛, 孟貴英, 趙學軍, 等. 醫院抗菌藥物應用調查分析[J]. 中華醫院感染學雜志, 2002, 12(12):930-932.
12. 韓佳音. 480例住院患者抗菌藥物應用與分析[J]. 中國預防醫學雜志, 2004, 5(3):194-197.
13. 陳彩芳, 黃建華, 譚秀燕. 抗菌藥物應用現狀調查及分析[J]. 中華醫院感染學雜志, 2004, 14(6):668-670.
14. Zarb P, Coignard B, Griskeviciene J, et al. The European centre for disease prevention and control (ECDC) pilot point prevalence survey of healthcare-associated infections and antimicrobial use[J]. Euro Surveill, 2012, 17(46):1-16.
15. Health Protection Agency. English national point prevalence survey on healthcare associated infections and antimicrobial use, 2011:preliminary data[EB/OL]. (2012-05-22)[2013-12-01]. http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1317134305239.

West China Medical Journal

Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011

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