Prevalence of Chronic Obstructive Pulmonary Disease with Lipid Metabolism Disorders in Chengdu_West China Medical Journal

Authors：

 WUJia , LIAOXiao-yang , PENGDa-qing , LIUXian-yuan ,  LEIYi

Department of General Practice, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

LEIYi, Email: 3371842@qq.com

Keywords：

Chronic obstructive pulmonary disease; Lipid metabolism disorders; Body mass index; Waistline

DOI：

10.7507/1002-0179.20140247

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the prevalence of chronic obstructive pulmonary disease (COPD) with lipid metabolism disorders patients in Chengdu. Methods We randomly selected four communities from urban and rural areas in Chengdu between February and December, 2010, with multistage cluster random sampling method; 1 931 residents aged from 40 to 70 received special questionnaire from the BOLD Study, lung examination, blood biochemical examination, and physical examination. Results The prevalence of COPD was 60.26% (91/151) with dyslipidemia; while non-COPD was 68.17% (972/1 428), and the difference was significant (P<0.05), in which the most obvious difference is triglycerides (TG). The prevalence of COPD was 6.62% (10/151) with underweight; while non-COPD was 4.97% (71/1 428), and the difference was significant (P<0.001). The prevalence of COPD was 21.19% (32/151) with abdominal obesity; while non-COPD was 30.81% (440/1 428), and the difference was significant (P<0.05). Conclusion The prevalence of COPD with lipid metabolism disorders is lower than which with non-COPD in Chengdu. It provides an evidence for the nutrition support therapy in the treatment of COPD.

Citation： WUJia, LIAOXiao-yang, PENGDa-qing, LIUXian-yuan, LEIYi. Prevalence of Chronic Obstructive Pulmonary Disease with Lipid Metabolism Disorders in Chengdu. West China Medical Journal, 2014, 29(5): 806-808. doi: 10.7507/1002-0179.20140247 Copy

1.	中華醫學會呼吸病學分會慢性阻塞性肺疾病學組. 慢性阻塞性肺疾病診治指南(2013年修訂版)(二)[J]. 全科醫學臨床與教育, 2013, 36(6):603-607.
2.	Zhong N, Wang C, Yao W, et al. Prevalence of chronic obstructive pulmonary disease in China:a large, population-based survey[J]. Am J Respir Crit Care Med, 2007, 176(8):753-760.
3.	曾雪峰, 王曉霞, 包勇, 等. 成都市社區慢性阻塞性肺疾病流行病學調查[J]. 中國呼吸與危重監護雜志, 2011, 10(1):30-32.
4.	Feary JR, Rodrigues LC, Smith CJ, et al. Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke:a comprehensive analysis using data from primary care[J]. Thorax, 2010, 65(11):956-962.
5.	常春, 姚婉貞, 方天舒. 慢性阻塞性肺疾病患者死因構成及其生存時間的影響因素[J]. 中華醫學雜志, 2011, 91(12):824-827.
6.	王曾禮. 重視慢性阻塞性肺疾病的共病[J]. 中華內科雜志, 2011, 50(6):456-458.
7.	Buist AS, Mcburnie MA, Vollmer WM, et al. International variation in the prevalence of COPD (the BOLD Study):a population-based prevalence study[J]. Lancet, 2007, 370(9589):741-750.
8.	中華醫學會呼吸病學分會慢性阻塞性肺疾病學組. 慢性阻塞性肺疾病診治指南(2007年修訂版)[J]. 中華內科雜志, 2007, 30(3):254-261.
9.	Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry[J]. Eur Respir J, 2005, 26(2):319-338.
10.	中國成人血脂異常防治指南制訂聯合委員會. 中國成人血脂異常防治指南[J]. 中華心血管病雜志, 2007, 35(5):390-419.
11.	中華醫學會糖尿病分會. 2007年版中國2型糖尿病防治指南[J]. 中華內分泌代謝雜志, 2008, 24(2):增錄1-附錄26.
12.	吳文彬. 慢性阻塞性肺疾病糖脂代謝的研究現狀[J]. 內科, 2011, 6(3):245-248.
13.	趙華昌, 李曉萍, 張倩. 慢性阻塞性肺疾病與血脂關系的臨床探討[J]. 現代預防醫學, 2007, 34(6):1194-1195.
14.	Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue[J]. Nature, 1994, 372(655):425-432.
15.	Wouters EF, Groenewegen KH, Dentener MA, et al. Systemic inflammation in chronic obstructive pulmonary disease:the role of exacerbations[J]. Proc Am Thorac Soc, 2007, 4(8):626-634.
16.	程靜, 葉碧綠, 李春洋. 小劑量激素替代治療對絕經后婦女心血管系統的影響[J]. 中國老年學雜志, 2005, 25(11):1308-1310.
17.	崔華, 魏致民, 蔡建芳, 等. 2000~2010年間4960例慢性阻塞性肺病住院患者合并高血壓和糖/脂代謝紊亂情況調查[J]. 南方醫科大學學報, 2011, 31(9):1498-1503.
18.	黃志儉, 羅琴, 凌敏, 等. 慢性阻塞性肺病體重指數與肺功能的相關性研究[J]. 臨床肺科雜志, 2009, 14(1):14-16.
19.	Celli BR, Cote CG, Marin JM, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease[J]. N England Med, 2004, 350(10):1005-1012.
20.	張明科, 徐治波, 譚珂, 等. 慢性阻塞性肺疾病患者肺功能與體重指數的關系研究[J]. 華西醫學, 2008, 23(4):744-745.

1. 中華醫學會呼吸病學分會慢性阻塞性肺疾病學組. 慢性阻塞性肺疾病診治指南(2013年修訂版)(二)[J]. 全科醫學臨床與教育, 2013, 36(6):603-607.
2. Zhong N, Wang C, Yao W, et al. Prevalence of chronic obstructive pulmonary disease in China:a large, population-based survey[J]. Am J Respir Crit Care Med, 2007, 176(8):753-760.
3. 曾雪峰, 王曉霞, 包勇, 等. 成都市社區慢性阻塞性肺疾病流行病學調查[J]. 中國呼吸與危重監護雜志, 2011, 10(1):30-32.
4. Feary JR, Rodrigues LC, Smith CJ, et al. Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke:a comprehensive analysis using data from primary care[J]. Thorax, 2010, 65(11):956-962.
5. 常春, 姚婉貞, 方天舒. 慢性阻塞性肺疾病患者死因構成及其生存時間的影響因素[J]. 中華醫學雜志, 2011, 91(12):824-827.
6. 王曾禮. 重視慢性阻塞性肺疾病的共病[J]. 中華內科雜志, 2011, 50(6):456-458.
7. Buist AS, Mcburnie MA, Vollmer WM, et al. International variation in the prevalence of COPD (the BOLD Study):a population-based prevalence study[J]. Lancet, 2007, 370(9589):741-750.
8. 中華醫學會呼吸病學分會慢性阻塞性肺疾病學組. 慢性阻塞性肺疾病診治指南(2007年修訂版)[J]. 中華內科雜志, 2007, 30(3):254-261.
9. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry[J]. Eur Respir J, 2005, 26(2):319-338.
10. 中國成人血脂異常防治指南制訂聯合委員會. 中國成人血脂異常防治指南[J]. 中華心血管病雜志, 2007, 35(5):390-419.
11. 中華醫學會糖尿病分會. 2007年版中國2型糖尿病防治指南[J]. 中華內分泌代謝雜志, 2008, 24(2):增錄1-附錄26.
12. 吳文彬. 慢性阻塞性肺疾病糖脂代謝的研究現狀[J]. 內科, 2011, 6(3):245-248.
13. 趙華昌, 李曉萍, 張倩. 慢性阻塞性肺疾病與血脂關系的臨床探討[J]. 現代預防醫學, 2007, 34(6):1194-1195.
14. Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue[J]. Nature, 1994, 372(655):425-432.
15. Wouters EF, Groenewegen KH, Dentener MA, et al. Systemic inflammation in chronic obstructive pulmonary disease:the role of exacerbations[J]. Proc Am Thorac Soc, 2007, 4(8):626-634.
16. 程靜, 葉碧綠, 李春洋. 小劑量激素替代治療對絕經后婦女心血管系統的影響[J]. 中國老年學雜志, 2005, 25(11):1308-1310.
17. 崔華, 魏致民, 蔡建芳, 等. 2000~2010年間4960例慢性阻塞性肺病住院患者合并高血壓和糖/脂代謝紊亂情況調查[J]. 南方醫科大學學報, 2011, 31(9):1498-1503.
18. 黃志儉, 羅琴, 凌敏, 等. 慢性阻塞性肺病體重指數與肺功能的相關性研究[J]. 臨床肺科雜志, 2009, 14(1):14-16.
19. Celli BR, Cote CG, Marin JM, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease[J]. N England Med, 2004, 350(10):1005-1012.
20. 張明科, 徐治波, 譚珂, 等. 慢性阻塞性肺疾病患者肺功能與體重指數的關系研究[J]. 華西醫學, 2008, 23(4):744-745.

Previous Article
Analysis of Standardized Training System of General Practitioners
Next Article
A Cross-sectional Study of the Prevalence and Risk Factors for Hypertension in Women from Chengdu Communities

West China Medical Journal

Prevalence of Chronic Obstructive Pulmonary Disease with Lipid Metabolism Disorders in Chengdu

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content