Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis_West China Medical Journal

Authors：

 HEYue , SHIXiao-ying , WANGChun-mei , WANGYong-zhi , LIRong

The Third General Ward, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

Keywords：

Renal transplantation; Hemodialysis; Quality of life; Prospective

DOI：

10.7507/1002-0179.20140378

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Objective To compare the quality of life in the early stage of treatment in patients who accepted renal transplantation with those who still were undergoing long-term hemodialysis. Methods Patients undergoing long-term hemodialysis in December 2011 and adult patients who planned to accept renal transplantation within 6 months were chosen to be our study subjects. The Medical Outcomes Study 36-item Short Form Health Survey Questionnaire (SF-36) was used for the study. After 6 months of following up, they were assessed with the same questionnaire again. Those hemodialysis patients who accepted renal transplantation within this period were divided into the intervention group. The quality of life between the two groups was compared then. Results A total of 124 end-stage renal failure patients were involved in our study, in which 79 patients successfully accepted renal transplantation (intervention group) and the other 45 patients who still underwent hemodialysis (control group). No other complications were observed during this period. There was no significant difference in life quality between the two groups before treatment (P>0.05). Six months after the treatment, SF-36 total score and each of the 8 dimension scores for the intervention group were all significantly higher than those for the control group (P<0.05). Conclusion Renal transplantation recipients have a totally better life quality than those who depend on hemodialysis.

Citation： HEYue, SHIXiao-ying, WANGChun-mei, WANGYong-zhi, LIRong. Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis. West China Medical Journal, 2014, 29(7): 1229-1233. doi: 10.7507/1002-0179.20140378 Copy

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2.	Panagopoulou A, Hardalias A, Berati S, et al. Psychosocial issues and quality of life in patients on renal replacement therapy[J]. Saudi J Kidney Dis Transpl, 2009, 20(2):212-218.
3.	陳灝珠, 林果為. 實用內科學[M]. 10版. 北京:人民衛生出版社, 2009:1775.
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6.	鄧燕青, 徐濤, 祖麗安, 等. 腎移植后患者生活質量評分專用量表的制訂及相關因素分析[J]. 護理學雜志, 2006, 21(24):7-10.
7.	王芳, 何強, 洪大情, 等. 持續靜靜脈血液濾過和持續低效每日透析治療重癥急性腎損傷的臨床研究[J]. 中國血液凈化, 2011, 10(6):306-309.
8.	張佩芳, 徐勤芳, 譚曉珍. 親屬活體腎移植供者術后生活質量與社會支持的調查研究[J]. 護理研究, 2010, 24(13):1142-1144.
9.	郭宏波. 腎移植與血液透析患者生活質量對比[J]. 中國組織工程研究與臨床康復, 2008, 12(31):6117-6121.
10.	Tavallaii SA, Einollahi B, Azizabadi Farahani M, et al. Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients[J]. Iran J Kidney Dis, 2009, 3(1):40-44.
11.	李剛, 馬潞林, 黃毅, 等. 不同年齡段活體供腎者的安全性[J]. 北京大學學報·醫學版, 2012, 44(4):646-648.
12.	周山, 劉宏, 余榮杰, 等. 腎移植受體93例生存質量調查研究[J]. 第三軍醫大學學報, 2010, 32(15):1652-1655.
13.	蔡善榮. 健康相關生命質量的研究概況[J]. 國外醫學·社會醫學分冊, 1999, 16(1):4-7.
14.	周英, 尤黎明. 腎移植相關心理問題及其影響因素的研究進展[J]. 中國行為醫學科學, 2002, 11(5):595-596.
15.	Frazier PA, Davis-Ali SH, Dahl KE. Correlates of noncompliance among renal transplant recipients[J]. Clin Transplant, 1994, 8(6):550-557.

1. Kalender B, Ozdemir AC, Dervisoglu E, et al. Quality of life in chronic kidney disease:effects of treatment modality, depression, malnutrition and inflammation[J]. Int J Clin Pract, 2007, 61(4):569-576.
2. Panagopoulou A, Hardalias A, Berati S, et al. Psychosocial issues and quality of life in patients on renal replacement therapy[J]. Saudi J Kidney Dis Transpl, 2009, 20(2):212-218.
3. 陳灝珠, 林果為. 實用內科學[M]. 10版. 北京:人民衛生出版社, 2009:1775.
4. Olss?n I, Mykletun A, Dahl AA. The hospital anxiety and depression rating scale:a cross-sectional study of psychometrics and case finding abilities in general practice[J]. BMC Psychiatry, 2005, 5(4):46.
5. 張作記. 行為醫學量表手冊[M]. 北京:中華醫學電子音像出版社, 2005:54-59.
6. 鄧燕青, 徐濤, 祖麗安, 等. 腎移植后患者生活質量評分專用量表的制訂及相關因素分析[J]. 護理學雜志, 2006, 21(24):7-10.
7. 王芳, 何強, 洪大情, 等. 持續靜靜脈血液濾過和持續低效每日透析治療重癥急性腎損傷的臨床研究[J]. 中國血液凈化, 2011, 10(6):306-309.
8. 張佩芳, 徐勤芳, 譚曉珍. 親屬活體腎移植供者術后生活質量與社會支持的調查研究[J]. 護理研究, 2010, 24(13):1142-1144.
9. 郭宏波. 腎移植與血液透析患者生活質量對比[J]. 中國組織工程研究與臨床康復, 2008, 12(31):6117-6121.
10. Tavallaii SA, Einollahi B, Azizabadi Farahani M, et al. Socioeconomic links to health-related quality of life, anxiety, and depression in kidney transplant recipients[J]. Iran J Kidney Dis, 2009, 3(1):40-44.
11. 李剛, 馬潞林, 黃毅, 等. 不同年齡段活體供腎者的安全性[J]. 北京大學學報·醫學版, 2012, 44(4):646-648.
12. 周山, 劉宏, 余榮杰, 等. 腎移植受體93例生存質量調查研究[J]. 第三軍醫大學學報, 2010, 32(15):1652-1655.
13. 蔡善榮. 健康相關生命質量的研究概況[J]. 國外醫學·社會醫學分冊, 1999, 16(1):4-7.
14. 周英, 尤黎明. 腎移植相關心理問題及其影響因素的研究進展[J]. 中國行為醫學科學, 2002, 11(5):595-596.
15. Frazier PA, Davis-Ali SH, Dahl KE. Correlates of noncompliance among renal transplant recipients[J]. Clin Transplant, 1994, 8(6):550-557.

West China Medical Journal

Prospective Cohort Study on Quality of Life in Patients Undergoing Renal Transplantation or Hemodialysis

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