Application of Vacuum-assisted Closure in the Treatment of Venous Ulcer of Lower Extremities_West China Medical Journal

Authors：

 CAIQiu-ni ,  LUWei-feng , YANGDong-hai , HUANGXiao-jin , ZHANGSu-zhen , CHENCai-cha

Department of Vascular Surgery, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian 361003, P. R. China;

Corresponding?author：

LUWei-feng, Email: luweifeng1976@gmail.com

Keywords：

Vacuum-assisted closure; Venous ulcer of lower extremities; Healing

DOI：

10.7507/1002-0179.20140493

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To analyze the clinical effect of vacuum-assisted closure in treating venous ulcer. Methods Thirty seven patients including 21 males and 16 females with lower extremity venous ulcer treated in our hospital from January 2013 to January 2014 were included in our study. Based on random number table, the patients were divided into treatment group [n=19, (66.47±6.22) years old] and control group [n=18, (66.39±5.37) years old]. The treatment group received vacuum-assisted closure, while the control group underwent routine moist therapy. Wound healing and visual analogue pain scores were observed. Chi-square test and t-test were used for statistical analysis. Results Wound healing rate was 84.2% in the treatment group and 55.6% in the control group, and the difference between the two groups was statistically significant (χ²=26.66, P<0.05). Wound healing time was (13.84±3.13) days in the treatment group and (27.35±1.73) days in the control group, and the difference was statistically significant (t=-7.498, P<0.01). Visual analogue pain scores in the treatment group was 3.53±0.51, and in the control group, it was 4.41±0.51, and the difference was statistically significant (t=-5.197, P<0.01). Conclusion Vacuum-assisted closure can significantly improve wound healing and alleviate sufferings in the treatment of venous ulcer.

Citation： CAIQiu-ni, LUWei-feng, YANGDong-hai, HUANGXiao-jin, ZHANGSu-zhen, CHENCai-cha. Application of Vacuum-assisted Closure in the Treatment of Venous Ulcer of Lower Extremities. West China Medical Journal, 2014, 29(9): 1603-1606. doi: 10.7507/1002-0179.20140493 Copy

1.	Morykwas MJ,Argenta LC,Shelton-Brown EI,et al.Vacuum-assisted closure:a new method for wound control and treatment:animal studies and basic foundation[J].Ann Plast Surg,1997,38(6):553-562.
2.	馮友賢.血管外科學[M].2版.上海:上海科學技術出版社,1992:506-507.
3.	王寧華.疼痛定量評定的進展[J].中國臨床康復,2002,6(18):2738-2739.
4.	李偉,史志.下肢靜脈曲張伴慢性潰瘍32例外科治療分析[J].重慶醫學,2007,36(21):2208-2210.
5.	王新江,馬文龍,杜志軍,等.VSD結合游離植皮治療兒童下肢大面積皮膚缺損[J].組織工程與重建外科雜志,2013,9(1):35-36.
6.	韓家宏,雷楚林,李仁鵬.負壓封閉引流技術在下肢大面積皮膚缺損合并感染的應用[J].組織工程與重建外科雜志,2010,6(4):206-207.
7.	曲家富,閆榮亮,王良,等.負壓封閉引流技術結合肌瓣轉移游離植皮治療小腿及足踝部軟組織缺損伴骨外露[J].中華創傷骨科雜志,2013,15(4):316-319.
8.	Furlanetti LL,De Oliveira RS,Santos MV,et al.Multiple cranial burr holes as an alternative treatment for total scalp avulsion[J].Childs Nerv Syst,2010,26(6):745-749.
9.	王靜,秦霞,余艷萍,等.負壓技術聯合濕性敷料在慢性傷口護理中的應用[J].護理研究,2014,28(2):217-218.
10.	Andros G,Armstrong DG,Attinger CE,et al.Consensus statement on negative pressure wound therapy (V.A.C.Therapy) for the management of diabetic foot wounds[J].Ostomy Wound Manage,2006,Suppl:1-32.
11.	蔣琪霞,劉云,徐薇,等.負壓傷口治療關鍵技術的研究進展[J].醫學研究生學報,2007,20(6):656-659.
12.	Steiling H,Werner S.Fibroblast growth factors:key players in epithelial morphogenesis,repair and cytoprotection[J].Curr Opin Biotechnol,2003,14(5):533-537.
13.	Dykes PJ,Heggie R,Hill SA.Effects of adhesive dressings on the stratum corneum of the skin[J].J Wound Care,2001,10(2):7-10.
14.	Maume S,Van De Looverbosch D,Heyman H,et al.A study to compare a new self-adherent soft silicone dressing with a self-adherent polymer dressing in stage Ⅱ pressure ulcers[J].Ostomy Wound Manage,2003,49(9):44-51.
15.	White R.A multinational survey of the assessment of pain when removing dressings[J].Wounds UK,2008,4(1):14-22.

1. Morykwas MJ,Argenta LC,Shelton-Brown EI,et al.Vacuum-assisted closure:a new method for wound control and treatment:animal studies and basic foundation[J].Ann Plast Surg,1997,38(6):553-562.
2. 馮友賢.血管外科學[M].2版.上海:上海科學技術出版社,1992:506-507.
3. 王寧華.疼痛定量評定的進展[J].中國臨床康復,2002,6(18):2738-2739.
4. 李偉,史志.下肢靜脈曲張伴慢性潰瘍32例外科治療分析[J].重慶醫學,2007,36(21):2208-2210.
5. 王新江,馬文龍,杜志軍,等.VSD結合游離植皮治療兒童下肢大面積皮膚缺損[J].組織工程與重建外科雜志,2013,9(1):35-36.
6. 韓家宏,雷楚林,李仁鵬.負壓封閉引流技術在下肢大面積皮膚缺損合并感染的應用[J].組織工程與重建外科雜志,2010,6(4):206-207.
7. 曲家富,閆榮亮,王良,等.負壓封閉引流技術結合肌瓣轉移游離植皮治療小腿及足踝部軟組織缺損伴骨外露[J].中華創傷骨科雜志,2013,15(4):316-319.
8. Furlanetti LL,De Oliveira RS,Santos MV,et al.Multiple cranial burr holes as an alternative treatment for total scalp avulsion[J].Childs Nerv Syst,2010,26(6):745-749.
9. 王靜,秦霞,余艷萍,等.負壓技術聯合濕性敷料在慢性傷口護理中的應用[J].護理研究,2014,28(2):217-218.
10. Andros G,Armstrong DG,Attinger CE,et al.Consensus statement on negative pressure wound therapy (V.A.C.Therapy) for the management of diabetic foot wounds[J].Ostomy Wound Manage,2006,Suppl:1-32.
11. 蔣琪霞,劉云,徐薇,等.負壓傷口治療關鍵技術的研究進展[J].醫學研究生學報,2007,20(6):656-659.
12. Steiling H,Werner S.Fibroblast growth factors:key players in epithelial morphogenesis,repair and cytoprotection[J].Curr Opin Biotechnol,2003,14(5):533-537.
13. Dykes PJ,Heggie R,Hill SA.Effects of adhesive dressings on the stratum corneum of the skin[J].J Wound Care,2001,10(2):7-10.
14. Maume S,Van De Looverbosch D,Heyman H,et al.A study to compare a new self-adherent soft silicone dressing with a self-adherent polymer dressing in stage Ⅱ pressure ulcers[J].Ostomy Wound Manage,2003,49(9):44-51.
15. White R.A multinational survey of the assessment of pain when removing dressings[J].Wounds UK,2008,4(1):14-22.

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West China Medical Journal

Application of Vacuum-assisted Closure in the Treatment of Venous Ulcer of Lower Extremities

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