Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection_West China Medical Journal

Authors：

 LIUJun-feng , TANZhao-hui , LIXing-zhi , CHINing ,  LISan-xiang

Department of Urology, Inner Mongolia People's Hospital, Huhehaote, Inner Mongolia 010017, P. R. China;

Corresponding?author：

LISan-xiang, Email: 2294474817@qq.com

Keywords：

Cystitis glandularis; Early intravesical instillation; Effect

DOI：

10.7507/1002-0179.20140561

Video：

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Objective To evaluate the clinical effect of early and deferred intravesical instillation in the treatment of cystitis glandularis after transurethral resection (TUR). Methods We retrospectively analyzed the clinical data of 95 patients with cystitis glandularis during February 2007 to April 2012. Among them, 37 patients underwent the first intravesical instillation within 24 hours after transurethral resection (group A), while the others underwent the same treatment within a week (group B). Then, intravesical instillation in all patients were carried out once every week for 8 weeks, and after that, it was carried out once every month for 5 to 10 months. All the patients were followed up for 12 to 16 months. The cure rate, improvement rate, total effective rate, recurrence rate and incidence of adverse events associated with therapy were observed. Results Recovery rate, improvement rate, side effects were observed in group A and B respectively, and there was no significant difference between the two groups (P>0.05). But there was significant difference in the total effective rate and recurrence rate (P<0.05). Conclusion The first intravesical instillation within 24 hours after transurethral resection in the treatment of cystitis glandularis can improve curative effect and lower recurrence rate, without the increase of side effects.

Citation： LIUJun-feng, TANZhao-hui, LIXing-zhi, CHINing, LISan-xiang. Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection. West China Medical Journal, 2014, 29(10): 1841-1844. doi: 10.7507/1002-0179.20140561 Copy

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2.	Jost SP, Dixon JS, Gosling JA, et al. Ultrastructural observations on cystitis cystica in human bladder urothelium[J]. Br J Urol, 1993, 71(1):2833.
3.	容偉超, 陳國威, 區文貴. 經尿道等離子電切病灶加膀胱灌注吡柔比星預防腺性膀胱炎復發的臨床研究[J]. 中國內鏡雜志, 2012, 18(3):288-290.
4.	朱建強, 王永傳. 腺性膀胱炎的再認識[J]. 醫學綜述, 2013, 19(3):493-496.
5.	王亞榮, 唐偉, 喻備, 等. 單純TUR與TUR聯合THP膀胱灌注治療腺性膀胱炎的Meta分析[J]. 重慶醫學, 2013, 42(11):1213-1215.
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9.	崔飛倫, 孫穎浩, 邱鎮, 等. 經尿道等離子電切加絲裂霉素膀胱灌注治療腺性膀胱炎56例[J]. 醫學臨床研究, 2005, 22(11):1595-1597.
10.	吳水清, 徐冉, 朱煊, 等. 腺性膀胱炎的治療進展[J]. 中華臨床醫師雜志·電子版, 2013, 7(18):8379-8381.
11.	應俊. 對腺性膀胱炎治療的再認識[J]. 中國全科醫學, 2008, 11(8):683-684.
12.	鄧健. 腺性膀胱炎60例的臨床診治體會[J]. 華西醫學, 2010, 25(1):39-40.
13.	龍清志, 劉潤明. 腺性膀胱炎灌注治療有效[J]. 現代泌尿外科雜志, 2012, 17(6):602-603.
14.	任尚青, 候琳, 鄧實, 等. 腺性膀胱炎的診斷與治療[J]. 四川大學學報·醫學版, 2012, 43(6):959-960.
15.	陳月軍, 拱華. 經尿道電切電灼術聯合吡柔比星膀胱灌注治療女性腺性膀胱炎48例報告[J]. 臨床泌尿外科雜志, 2012, 27(3):222-223.
16.	曾小明, 熊海云, 余明主, 等. 經尿道等離子汽化電切聯合術后吡柔比星膀胱灌注治療腺性膀胱炎[J]. 南昌大學學報·醫學版, 2013, 53(7):19-21.
17.	熊林, 余書勇, 鄒茜, 等. 經尿道超脈沖等離子體雙極電切術聯合膀胱灌注化療治療腺性膀胱炎44例[J]. 中華腔鏡泌尿外科雜志·電子版, 2012, 6(2):39-41.
18.	張朝華, 黃研, 彭洪濤, 等. 吡柔比星膀胱灌注治療腺性膀胱炎46例[J]. 中國藥業, 2009, 18(13):77-78.
19.	宋東奎, 邢東亮. 經尿道汽化術聯合吡柔比星膀胱保留灌注治療腺性膀胱炎[J]. 腫瘤研究與臨床, 2005, 17(6):413-414.

1. 姚友生, 林明恩. 腺性膀胱炎診療新進展[J]. 廣東醫學, 2010, 31(1):45-46.
2. Jost SP, Dixon JS, Gosling JA, et al. Ultrastructural observations on cystitis cystica in human bladder urothelium[J]. Br J Urol, 1993, 71(1):2833.
3. 容偉超, 陳國威, 區文貴. 經尿道等離子電切病灶加膀胱灌注吡柔比星預防腺性膀胱炎復發的臨床研究[J]. 中國內鏡雜志, 2012, 18(3):288-290.
4. 朱建強, 王永傳. 腺性膀胱炎的再認識[J]. 醫學綜述, 2013, 19(3):493-496.
5. 王亞榮, 唐偉, 喻備, 等. 單純TUR與TUR聯合THP膀胱灌注治療腺性膀胱炎的Meta分析[J]. 重慶醫學, 2013, 42(11):1213-1215.
6. 劉哲, 胡茂勝, 黃德波. 腺性膀胱炎治療方式選擇的探討[J]. 湖南中醫藥大學學報, 2009, 29(11):72-75.
7. 侯琳, 屈銳, 任尚青, 等. 經尿道電切后化療藥物灌注治療腺性膀胱炎療效的系統評價[J]. 中國循證醫學雜志, 2012, 12(10):1251-1260.
8. Lee G, Tsiriopoulos I, Yajnik K, et al. Case report:cystitis glandu-laris mimics bladder tumour:a case report and diagnostic character-istics[J]. Int Urol Nephrol, 2005, 37(4):713-715.
9. 崔飛倫, 孫穎浩, 邱鎮, 等. 經尿道等離子電切加絲裂霉素膀胱灌注治療腺性膀胱炎56例[J]. 醫學臨床研究, 2005, 22(11):1595-1597.
10. 吳水清, 徐冉, 朱煊, 等. 腺性膀胱炎的治療進展[J]. 中華臨床醫師雜志·電子版, 2013, 7(18):8379-8381.
11. 應俊. 對腺性膀胱炎治療的再認識[J]. 中國全科醫學, 2008, 11(8):683-684.
12. 鄧健. 腺性膀胱炎60例的臨床診治體會[J]. 華西醫學, 2010, 25(1):39-40.
13. 龍清志, 劉潤明. 腺性膀胱炎灌注治療有效[J]. 現代泌尿外科雜志, 2012, 17(6):602-603.
14. 任尚青, 候琳, 鄧實, 等. 腺性膀胱炎的診斷與治療[J]. 四川大學學報·醫學版, 2012, 43(6):959-960.
15. 陳月軍, 拱華. 經尿道電切電灼術聯合吡柔比星膀胱灌注治療女性腺性膀胱炎48例報告[J]. 臨床泌尿外科雜志, 2012, 27(3):222-223.
16. 曾小明, 熊海云, 余明主, 等. 經尿道等離子汽化電切聯合術后吡柔比星膀胱灌注治療腺性膀胱炎[J]. 南昌大學學報·醫學版, 2013, 53(7):19-21.
17. 熊林, 余書勇, 鄒茜, 等. 經尿道超脈沖等離子體雙極電切術聯合膀胱灌注化療治療腺性膀胱炎44例[J]. 中華腔鏡泌尿外科雜志·電子版, 2012, 6(2):39-41.
18. 張朝華, 黃研, 彭洪濤, 等. 吡柔比星膀胱灌注治療腺性膀胱炎46例[J]. 中國藥業, 2009, 18(13):77-78.
19. 宋東奎, 邢東亮. 經尿道汽化術聯合吡柔比星膀胱保留灌注治療腺性膀胱炎[J]. 腫瘤研究與臨床, 2005, 17(6):413-414.

West China Medical Journal

Comparison between the Clinical Outcome of Early and Deferred Intravesical Instillation Therapy in Treating Cystitis Glandularis after Transurethral Resection

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