Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation_West China Medical Journal

Authors：

 JIANGPeng , HUHai , HEYa-rong ,  CAOYu

Emergency Department, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

CAOYu, Email: yuyuer@126.com

Keywords：

Return of spontaneous circulation; Cox regression analysis; Survival time; Prognosis

DOI：

10.7507/1002-0179.20150295

Video：

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Objective To find out the possible factors that may affect the survival time of patients undergoing return of spontaneous circulation (ROSC) within seven days of cardio-pulmonary resuscitation. Method We retrospectively collected 20 clinical indicators from 51 patients who underwent ROSC after cardio-pulmonary resuscitation in Emergency Department between August 2013 and February 2015. The indicators included gender, age, duration of cardio-pulmonary resuscitation, blood pressure acquired immediately after ROSC, heart rate, respiration, lactic acid, creatinine, prothrombin time, bilirubin, pH, arterial partial pressure of carbon dioxide, potassium, sodium, blood glucose, atrial natriuretic peptides, leukocyte, platelets, and hemoglobin. Then we analyzed the correlation of these indicators with survival time through Cox regression model. Results The results showed that duration of cardiopulmonary resuscitation[RR=1.053, 95% CI (1.020, 1.088), P=0.002] and systolic blood pressure acquired immediately after ROSC[RR=0.991, 95% CI (0.982, 0.999), P=0.038] significantly affected the survival time of patients after ROSC. Conclusions Duration of cardiopulmonary resuscitation and systolic blood pressure acquired immediately after ROSC may be useful in predicting the survival time of patients after ROSC.

Citation： JIANGPeng, HUHai, HEYa-rong, CAOYu. Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation. West China Medical Journal, 2015, 30(6): 1027-1030. doi: 10.7507/1002-0179.20150295 Copy

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1. ECC Committee, Subcommittees and Task Forces of the American Heart Association. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care[J].Circulation, 2005, 112(124):IV1-IV 203.
2. Field JM, Hazinski MF, Sayre MR, et al. 2010 American heart association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care[J]. Circulation, 2010, 122(Suppl 3):S640-S656.
3. 胡海, 杜鑫淼, 張建成, 等. 心肺復蘇后自主循環恢復患者死亡風險預測及回歸模型建立[J]. 華西醫學, 2009, 24(9):2275-2277.
4. 袁偉安. 68例心肺復蘇成敗原因及對策分析[J]. 中外醫學研究, 2014, 12(8):125-126.
5. Neumar RW, Nolan JP, Adrie C, et al. Post-cardiac arrest syndrome:epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council[J]. CiRculation, 2008, 118(23):2452-2483.
6. 王澤惠, 王永進, 侯云生, 等. 心肺復蘇后多器官功能障礙綜合征臨床分析[J]. 中國急救醫學, 2005, 28(8):609-610.
7. 沈洪, 王士雯. 2003:中國心肺復蘇的關注問題[J]. 中國危重病急救醫學, 2003, 15(5):262-264.
8. Saghafinia M, Motamedi MH, Piryaie M, et al. Survival after in-hospital cardiopulmonary resuscitation in a major referral center[J]. Saudi J Anaesth, 2010, 4(2):68-71.
9. 張孝欽, 王興祥, 丁晨彥, 等. 心搏驟停心肺復蘇中若干問題的探討[J]. 中國全科醫學, 2006, 9(10):828-829.
10. 董揚. 心肺復蘇自主循環恢復患者預后相關因素分析[J]. 中國醫師進修雜志雜志, 2011, 34(18):55-56.
11. 丁旻珺, 謝娟. 心肺復蘇自主循環恢復患者預后相關因素分析[J]. 實用醫學雜志, 2012, 28(23):3956-3959.
12. Adrie C, Adib-Conquy M, Laurent I, et al. Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome[J]. Circulation, 2002, 106(5):562-568.
13. Thompson RJ, Mccullough PA, Kahn JK, et al. Prediction of death and neurologic outcome in the emergency department in out-of-hospital cardiac arrest survivors[J]. Am J Cardiol, 1998, 81(1):17-21.
14. 曾琦, 李詩陽, 譚世峰, 等. 心肺復蘇預后因素分析及對策[J]. 中國熱帶醫學, 2006, 6(4):659-660.
15. Laurent I, Monchi M, Chiche JD, et al. Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest[J]. J Am Coll Cardiol, 2002, 40(12):2110-2116.
16. Van Den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU[J]. N Engl J Med, 2006, 354(5):449-461.
17. 馮欣蘅, 崔華中, 韓溟, 等. 影響心肺復蘇后存活率的相關因素探討[J]. 實用醫學雜志, 2005, 21(17):1933-1934.
18. 梁實, 張文武, 韓冥, 等. 影響心肺復蘇存活率的相關因素探討[J]. 實用醫學雜志, 2005, 21(17):1934.

West China Medical Journal

Analysis of Related Factors Influencing the Early Survival Time of Patients Undergoing Return of Spontaneous Circulation after Cardio-pulmonary Resuscitation

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