Study of the Patterns and Predictors of Recurrent Stroke among Patients with Initial Ischemic Stroke_West China Medical Journal

Authors：

 ZHANGLi-lin , YANGCheng-rong , BAILiang

Department of Neurology, Ya'an People's Hospital, Ya'an, Sichuan 625000, P. R. China;

Corresponding?author：

Keywords：

Initial ischemic stroke; Recurrent stroke; Pattern; Risk factor

DOI：

10.7507/1002-0179.20150460

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Objective To analyze the patterns of recurrent strokes among patients with initial ischemic stroke and investigate the possible predictors of recurrent ischemic stroke. Method Patients with recurrent strokes after initial ischemic strokes hospitalized in our hospital between January 2008 and December 2012 were included in the study, and the data of general demographic information, life history, past medical history and laboratory test results were all retrospectively analyzed. The patterns of recurrent strokes in patients with initial ischemic stroke were analyzed, and multivariate logistic regression analysis was used to investigate the independent risk factors for recurrent ischemic stroke. Results A total of 237 patients were included in this study, including 198 patients with recurrent ischemic stroke and 39 patients with recurrent hemorrhagic stroke. Among patients with recurrent ischemic stroke, there were 137 patients with anterior circulation stroke, 52 with posterior circulation stroke and 9 with multiple infarction. Multivariate logistic regression analysis showed that older age at initial stroke onset[OR=1.968, 95%CI (1.533, 2.152), P=0.009], frequent mood swings[OR=1.345, 95%CI (1.121, 1.783), P=0.011], hyperlipidemia[OR=1.436, 95%CI (1.216, 1.732), P=0.018] and atrial fibrillation[OR=3.417, 95%CI (2.927, 4.897), P=0.005] were independent risk factors for recurrent ischemic stroke. Conclusions Ischemic stroke is the most common pattern of recurrent strokes; and aging, frequent mood swings, hyperlipidemia and atrial fibrillation are possible predictors of recurrent ischemic stroke after the initial ischemic stroke.

Citation： ZHANGLi-lin, YANGCheng-rong, BAILiang. Study of the Patterns and Predictors of Recurrent Stroke among Patients with Initial Ischemic Stroke. West China Medical Journal, 2015, 30(9): 1601-1604. doi: 10.7507/1002-0179.20150460 Copy

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14.	陳茁, 王俊雄, 魯旭陽, 等. 腦梗死中醫證型與血脂、血清Hcy水平表達的臨床研究[J]. 湖南中醫雜志, 2015, 31(6):4-6.
15.	劉國榮, 王大力, 張文麗, 等. 頸動脈易損斑塊與缺血性腦卒中復發的相關性研究[J]. 中華老年心腦血管病雜志, 2012, 14(10):1067-1070.
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17.	馬麗蘋, 王曉鵬, 高義. 老年缺血性腦卒中危險因素與藥物干預研究進展[J]. 臨床誤診誤治, 2015, 28(7):112-115.
18.	王紅彥, 程勇, 王培昌. 北京地區腦卒中高危人群血糖、血脂水平調查[J]. 河北醫藥, 2014, 36(10):1480-1481.
19.	Vemmos KN, Takis CE, Georgilis K, et al. The Athens stroke registry:results of a five-year hospital-based study[J]. Cerebrovasc Dis, 2000, 10(2):133-141.

1. 莊育, 宣董強, 方堃. 缺血性腦卒中再發風險預測的現況[J]. 中華腦血管病雜志:電子版, 2013, 7(1):398-403.
2. 翟青, 童曉欣. 青年缺血性腦卒中112例危險因素分析[J]. 卒中與神經疾病, 2013(3):162-165.
3. 吳建霞, 郭秀君, 楊復君, 等. 缺血性腦卒中復發危險因素的研究進展[J]. 中華現代護理雜志, 2011, 17(31):3829-3832.
4. 馮社軍, 劉鳴, 李衛征, 等. 腦卒中患者復發及其影響因素研究[J]. 南方醫科大學學報, 2009, 29(5):983-985.
5. 王丹. 缺血性腦卒中患者臨床治療對預后影響的臨床研究[J]. 中國醫藥指南, 2013, 11(8):149-150.
6. 林晶倩, 張愛娟, 楊麗芳, 等. 復發性腦卒中臨床及影像學研究[J]. 中國實用神經疾病雜志, 2013, 16(8):6-8.
7. 黃志萍, 蘇婭, 陳秀紅, 等. 腦卒中患者日常生活活動能力及其影響因素[J]. 中國老年學雜志, 2015, 35(10):2663-2665.
8. 張填, 王埮, 王淑榮. 老年缺血性腦卒中患者近期預后的影響因素[J]. 中國老年學雜志, 2014, 34(7):1754-1755.
9. 姚小英, 林巖, 耿介立, 等. 首發缺血性卒中后再發不同類型卒中預測因素的回歸性分析[J]. 中華神經科雜志, 2012, 45(11):769-773.
10. 鄭龍, 梅元武. 心房顫動所致缺血性卒中與抗凝治療的研究現狀[J]. 現代醫藥衛生, 2011, 27(7):1027-1028.
11. 許潔, 吳毅, 路微波, 等. 老年人缺血性腦卒中復發相關影響因素研究[J]. 中華全科醫師雜志, 2012, 11(3):215-216.
12. Bonita R. Epidemiology of stroke[J]. Lancet, 1992, 339(8789):342-344.
13. 王銀霞, 趙世剛, 張春雨, 等. 合并2型糖尿病的缺血性腦梗死復發危險因素研究[J]. 中西醫結合心腦血管病雜志, 2012, 10(9):1064-1066.
14. 陳茁, 王俊雄, 魯旭陽, 等. 腦梗死中醫證型與血脂、血清Hcy水平表達的臨床研究[J]. 湖南中醫雜志, 2015, 31(6):4-6.
15. 劉國榮, 王大力, 張文麗, 等. 頸動脈易損斑塊與缺血性腦卒中復發的相關性研究[J]. 中華老年心腦血管病雜志, 2012, 14(10):1067-1070.
16. 于慶海, 董彥慧. 老年腦卒中患者復發的危險因素臨床分析[J]. 河北醫學, 2015, 21(11):1880-1883.
17. 馬麗蘋, 王曉鵬, 高義. 老年缺血性腦卒中危險因素與藥物干預研究進展[J]. 臨床誤診誤治, 2015, 28(7):112-115.
18. 王紅彥, 程勇, 王培昌. 北京地區腦卒中高危人群血糖、血脂水平調查[J]. 河北醫藥, 2014, 36(10):1480-1481.
19. Vemmos KN, Takis CE, Georgilis K, et al. The Athens stroke registry:results of a five-year hospital-based study[J]. Cerebrovasc Dis, 2000, 10(2):133-141.

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