實時三維超聲心動圖評價缺血性二尖瓣反流的研究進展_West China Medical Journal

Authors：

 劉佳霓 , 白文娟 ,  唐紅

四川大學華西醫院心臟內科（成都 610041）;

Corresponding?author：

唐紅, Email: hxyyth@gmail.com

Keywords：

缺血性二尖瓣反流; 實時三維超聲心動圖; 研究進展

DOI：

10.7507/1002-0179.201600264

Video：

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缺血性二尖瓣反流（IMR）是冠狀動脈粥樣硬化性心臟病心肌梗死常見并發癥之一，增加患者心力衰竭和死亡的發生率。IMR 的形成機制復雜，目前研究尚未達成共識，導致IMR 治療措施不完善及標準。隨著三維超聲技術日趨成熟，實時三維超聲心動圖（RT3DE）將矩陣探頭、三維空間定位和高通道的數據處理系統3 種先進技術結合，不依賴任何幾何形態的假設，全面獲得心臟三維立體結構及動態改變。RT3DE 對深入研究IMR 發病機制，探討有效的臨床治療方法，評估病情進展、判斷治療效果、評價長期預后有重要臨床價值，可作為臨床評價IMR的首選方法。

Citation： 劉佳霓, 白文娟, 唐紅. 實時三維超聲心動圖評價缺血性二尖瓣反流的研究進展. West China Medical Journal, 2016, 31(5): 978-981. doi: 10.7507/1002-0179.201600264 Copy

1.	Arenson D, Goldsher N, Zukermann R , et al. Ischemic mitral regurgitation and risk of heart failure after myocardial infarction[J]. Arch Intern Med, 2006, 166(21): 2362-2368.
2.	Boyd JH. Ischemic mitral regurgitation[J]. Circ J, 2013, 77(8): 1952- 1956.
3.	張炬倩, 李晨, 饒莉. 缺血性二尖瓣反流的機制、診斷和治療研究進展[J]. 心血管病學進展, 2009, 30(6): 919-922．.
4.	黃國倩, 蔣字雯, 顏平, 等. 三維超聲心動圖定量評價二尖瓣反流患者的二尖瓣及瓣環幾何構型[J]. 中國介入影像與治療學, 2009, 6(4): 352-355．.
5.	Daimon M, Saracino G, Fukuda S, et al. Dynamic change of mitral annular geometry and motion in ischemic mitral regurgitation assessed by a computerized 3D echo method[J]. Echocardiography, 2010, 27(9): 1069-1077.
6.	Daimon M, Saracino G, Gillinov AM, et al. Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: a novel computerized 3D echocardiographic analysis[J]. Echocardiography, 2008 , 25(4): 414-423.
7.	Song JM, Fukuda S, Kihara T, et al. Value of mitral valve tenting volume determined by real time three-dimensional echocardiography in patients with functional mitral regurgitation[J]. Am J Cardiol, 2006, 98(8): 1088-1093．.
8.	Watanabe N, Ognsawara Y, Yamaura Y, et al. Quantification of mitral valve tenting in ischemic mitral regurgitation by transthoracie real-time three-dimensional echocardiography[J].J Am Coil Cardiol, 2005, 45(5): 763-769．.
9.	Tibayan FA, Wilson A, Lai DT, et al. Tenting volume: threedimensional assessment of geometric perturbations in functional mitral regurgitation and implications for surgical repair[J]. J Heart Valve Dis, 2007, 16(1): 1-7.
10.	Veronesi F, Corsi C, Sugeng L, et al. Quantification of mitral apparatus dynamics in functional and ischemic mitral regurgitation using real-time 3-dimensional echocardiography[J]. J Am Soc Echocardiogr, 2008, 21(4): 347-354.
11.	王林林, 何怡華, 陳健, 等. 實時三維TEE評價犬二尖瓣對合程度與二尖瓣反流程度的關系[J]. 中國醫學影像技術, 2012, 28(7): 1263-1267.
12.	賀林, 王新房, 謝明星, 等. 實時三維超聲心動圖對正常二尖瓣與功能性反流二尖瓣閉合線的對比研究[J]. 臨床超聲醫學雜志, 2010, 12(10): 665-669.
13.	Matsumura Y, Fukuda S, Tran H, et al. Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: difference between functional mitral regurgitation and prolapse regurgitation[J]. Am Heart J 2008, 155(2): 231-238.
14.	Song JM, Kim MJ, Kim YJ. Three-dimensional characteristics of functional mitral regurgitation in patients with severe left ventricular dysfunction: a real-time three-dimensional color Doppler echocardiography study [J]. Heart , 2008, 94(5): 590-596.
15.	LittIe S, Igo SR, Pirant B, et al. In UitrovaIidation of real-time three dimensional color Doppler echocardiography for direct measurement of proximal isovelocity surface area in mitral regurgitation [J]. Am J CardiaoI, 2007, 99(10): 1440-1447.
16.	Grady L, Datta S, Kutter O, et al. Regurgitation quantification using 3D PISA in volume echocardiography[J]. Med Image Comput Assist Interv, 2011, 14(3): 512-519.
17.	Little SH, Pirat B, Kumar R, et al. Three-dimensional color Doppler echocardiography for direct measurement of vena contracta area in mitral regurgitation: in vitro validation and clinical experience[J]. JACC Cardiovasc Imaging, 2008, 1(6): 695-704.
18.	Hyodo E, Iwata S, Tugcu A, et al. Direct measurement of multiple vena contracta areas for assessing the severity of mitral regurgitation using 3D TEE[J]. JACC Cardiovasc Imaging, 2012, 5(7): 669-676.
19.	Yosefy C, Hung J, Chua S, et al. Direct measurement of vena contracta area by real-time 3-dimensional echocardiography for assessing severity of mitral regurgitation[J]. Am J Cardiol, 2009, 104(7): 978-983.
20.	Zeng X, Levine RA, Hua L, et al. Diagnostic value of vena contracta area in the quantification of mitral regurgitation severity by color Doppler 3D echocardiography[J]. Circ Cardiovasc Imaging, 2011, 4(5): 506-513.
21.	Chandra S, SalgoI S, Sugeng L, et al. A three-dimensional insight into the complexity of flow convergence in mitralregurgitation: adjunctive benefit of anatomic regurgitant orifice area[J]. Am J Physiol Heart Circ Physiol, 2011, 301(3): 1015-1024.
22.	Altiok E, Hamada S, van HallS, et al. Comparison of direct planimetry of mitral valve regurgitation orifice area by threedimensional transesophageal echocardiography to effective regurgitant orifice area obtained by proximal flow convergence method and vena contracta area determined by color Doppler echocardiography[J]. Am J Cardiol, 2011, 107(3): 452-458.
23.	Thavendiranathan P, Liu S, Datta S, et al. Automated quantification of mitral inflow and aortic outflow stroke volumes by threedimensional real-time volume color-flow Doppler transthoracic echocardiography: comparison with pulsed-wave Doppler and cardiac magnetic resonance imaging[J]. J Am Soc Echocardiogr, 2012, 25(1): 56-65.
24.	王吳剛, 林瓊雯, 吳偉春, 等. 全身成像模式三維量化法評估二尖瓣反流體積與近端血流等速面法的對比研究[J]. 中國循環雜志, 2014, 29(1): 35-39.
25.	Abe Y, Imai T, Ohue K, et al. Relation between reduction in ischemic mitral regurgitation and improvement in regional left ventricular contractility during low dose dobutamine stress echocardiography[J]. Heart, 2005, 91(8): 1092-1093.
26.	文利, 高云華, 鄭嘉榮, 等. 實時三維超聲對慢性心肌缺血負荷前后左心室收縮同步性的實驗研究[J]. 中華超聲影像學雜志, 2010, 19(9): 806-810.

1. Arenson D, Goldsher N, Zukermann R , et al. Ischemic mitral regurgitation and risk of heart failure after myocardial infarction[J]. Arch Intern Med, 2006, 166(21): 2362-2368.
2. Boyd JH. Ischemic mitral regurgitation[J]. Circ J, 2013, 77(8): 1952- 1956.
3. 張炬倩, 李晨, 饒莉. 缺血性二尖瓣反流的機制、診斷和治療研究進展[J]. 心血管病學進展, 2009, 30(6): 919-922．.
4. 黃國倩, 蔣字雯, 顏平, 等. 三維超聲心動圖定量評價二尖瓣反流患者的二尖瓣及瓣環幾何構型[J]. 中國介入影像與治療學, 2009, 6(4): 352-355．.
5. Daimon M, Saracino G, Fukuda S, et al. Dynamic change of mitral annular geometry and motion in ischemic mitral regurgitation assessed by a computerized 3D echo method[J]. Echocardiography, 2010, 27(9): 1069-1077.
6. Daimon M, Saracino G, Gillinov AM, et al. Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: a novel computerized 3D echocardiographic analysis[J]. Echocardiography, 2008 , 25(4): 414-423.
7. Song JM, Fukuda S, Kihara T, et al. Value of mitral valve tenting volume determined by real time three-dimensional echocardiography in patients with functional mitral regurgitation[J]. Am J Cardiol, 2006, 98(8): 1088-1093．.
8. Watanabe N, Ognsawara Y, Yamaura Y, et al. Quantification of mitral valve tenting in ischemic mitral regurgitation by transthoracie real-time three-dimensional echocardiography[J].J Am Coil Cardiol, 2005, 45(5): 763-769．.
9. Tibayan FA, Wilson A, Lai DT, et al. Tenting volume: threedimensional assessment of geometric perturbations in functional mitral regurgitation and implications for surgical repair[J]. J Heart Valve Dis, 2007, 16(1): 1-7.
10. Veronesi F, Corsi C, Sugeng L, et al. Quantification of mitral apparatus dynamics in functional and ischemic mitral regurgitation using real-time 3-dimensional echocardiography[J]. J Am Soc Echocardiogr, 2008, 21(4): 347-354.
11. 王林林, 何怡華, 陳健, 等. 實時三維TEE評價犬二尖瓣對合程度與二尖瓣反流程度的關系[J]. 中國醫學影像技術, 2012, 28(7): 1263-1267.
12. 賀林, 王新房, 謝明星, 等. 實時三維超聲心動圖對正常二尖瓣與功能性反流二尖瓣閉合線的對比研究[J]. 臨床超聲醫學雜志, 2010, 12(10): 665-669.
13. Matsumura Y, Fukuda S, Tran H, et al. Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: difference between functional mitral regurgitation and prolapse regurgitation[J]. Am Heart J 2008, 155(2): 231-238.
14. Song JM, Kim MJ, Kim YJ. Three-dimensional characteristics of functional mitral regurgitation in patients with severe left ventricular dysfunction: a real-time three-dimensional color Doppler echocardiography study [J]. Heart , 2008, 94(5): 590-596.
15. LittIe S, Igo SR, Pirant B, et al. In UitrovaIidation of real-time three dimensional color Doppler echocardiography for direct measurement of proximal isovelocity surface area in mitral regurgitation [J]. Am J CardiaoI, 2007, 99(10): 1440-1447.
16. Grady L, Datta S, Kutter O, et al. Regurgitation quantification using 3D PISA in volume echocardiography[J]. Med Image Comput Assist Interv, 2011, 14(3): 512-519.
17. Little SH, Pirat B, Kumar R, et al. Three-dimensional color Doppler echocardiography for direct measurement of vena contracta area in mitral regurgitation: in vitro validation and clinical experience[J]. JACC Cardiovasc Imaging, 2008, 1(6): 695-704.
18. Hyodo E, Iwata S, Tugcu A, et al. Direct measurement of multiple vena contracta areas for assessing the severity of mitral regurgitation using 3D TEE[J]. JACC Cardiovasc Imaging, 2012, 5(7): 669-676.
19. Yosefy C, Hung J, Chua S, et al. Direct measurement of vena contracta area by real-time 3-dimensional echocardiography for assessing severity of mitral regurgitation[J]. Am J Cardiol, 2009, 104(7): 978-983.
20. Zeng X, Levine RA, Hua L, et al. Diagnostic value of vena contracta area in the quantification of mitral regurgitation severity by color Doppler 3D echocardiography[J]. Circ Cardiovasc Imaging, 2011, 4(5): 506-513.
21. Chandra S, SalgoI S, Sugeng L, et al. A three-dimensional insight into the complexity of flow convergence in mitralregurgitation: adjunctive benefit of anatomic regurgitant orifice area[J]. Am J Physiol Heart Circ Physiol, 2011, 301(3): 1015-1024.
22. Altiok E, Hamada S, van HallS, et al. Comparison of direct planimetry of mitral valve regurgitation orifice area by threedimensional transesophageal echocardiography to effective regurgitant orifice area obtained by proximal flow convergence method and vena contracta area determined by color Doppler echocardiography[J]. Am J Cardiol, 2011, 107(3): 452-458.
23. Thavendiranathan P, Liu S, Datta S, et al. Automated quantification of mitral inflow and aortic outflow stroke volumes by threedimensional real-time volume color-flow Doppler transthoracic echocardiography: comparison with pulsed-wave Doppler and cardiac magnetic resonance imaging[J]. J Am Soc Echocardiogr, 2012, 25(1): 56-65.
24. 王吳剛, 林瓊雯, 吳偉春, 等. 全身成像模式三維量化法評估二尖瓣反流體積與近端血流等速面法的對比研究[J]. 中國循環雜志, 2014, 29(1): 35-39.
25. Abe Y, Imai T, Ohue K, et al. Relation between reduction in ischemic mitral regurgitation and improvement in regional left ventricular contractility during low dose dobutamine stress echocardiography[J]. Heart, 2005, 91(8): 1092-1093.
26. 文利, 高云華, 鄭嘉榮, 等. 實時三維超聲對慢性心肌缺血負荷前后左心室收縮同步性的實驗研究[J]. 中華超聲影像學雜志, 2010, 19(9): 806-810.

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實時三維超聲心動圖評價缺血性二尖瓣反流的研究進展

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