脊柱骨纖維結構不良的診斷和治療研究進展_West China Medical Journal

Authors：

 胡星新 ,  劉立岷

四川大學華西醫院骨科（成都 610041）;

Corresponding?author：

劉立岷, Email: liu_spine@163.com

Keywords：

脊柱; 骨纖維結構不良; 研究進展

DOI：

10.7507/1002-0179.201600395

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

骨纖維結構不良（FD）是一種良性骨病，最常發生在四肢骨骼，而發生在脊柱部位的極少見。脊柱FD與其他部位骨骼的FD在臨床表現、影像學特征和治療方法上有許多不同，術前明確診斷較困難，針對其導致椎體骨質破壞或脊柱不穩定以及繼發的脊髓神經損害有多種治療方法，但在臨床上通常采用多種方法綜合治療。該文特就脊柱FD的臨床特征、診斷和治療方法作一綜述。

Citation： 胡星新, 劉立岷. 脊柱骨纖維結構不良的診斷和治療研究進展. West China Medical Journal, 2016, 31(8): 1453-1457. doi: 10.7507/1002-0179.201600395 Copy

1.	Park SK, Lee IS, Choi JY, et al. CT and MRI of fibrous dysplasia of the spine[J]. Br J Radiol, 2012, 85(1015):996-1001.
2.	周幸, 吳蘇稼, 施鑫. T-5椎體骨纖維結構不良1例報告[J].中國矯形外科雜志, 2011, 19(9):717.
3.	Harris WH, Dudley HR, Barry RJ. The natural history of fibrous dysplasia. An orthopaedic, pathological, and roentgenographic study[J]. J Bone Joint Surg Am, 1962, 44-A:207-233.
4.	Proschek D, Orler R, Stauffer E, et al. Monostotic fibrous dysplasia of the spine:report of a case involving a cervical vertebra[J]. Arch Orthop Trauma Surg, 2007, 127(2):75-79.
5.	Gogia N, Marwaha V, Atri S, et al. Fibrous dysplasia localized to spine:a diagnostic dilemma[J]. Skeletal Radiol, 2007, 36(Suppl 1):S19-S23.
6.	Leet AI, Magur E, Lee JS, et al. Fibrous dysplasia in the spine:prevalence of lesions and association with scoliosis[J]. J Bone Joint Surg Am, 2004, 86-A(3):531-537.
7.	Narayan RL, Maldjian PD. Restrictive lung disease and cor pulmonale secondary to polyostotic fibrous dysplasia[J]. Int J Cardiol, 2009, 131(2):e48-e50.
8.	Yang C, Zhu B, Chen A. Imaging diagnosis of monostotic fibrous dysplasia in thoracic and lumbar spine vertebrae[J]. J Huazhong Univ Sci Technolog Med Sci, 2007, 27(6):684-686.
9.	李杰, 呂梁.脊椎骨纖維異常增殖癥的CT診斷[J].中國臨床醫學影像雜志, 2009, 20(5):316-318.
10.	Wu FL, Jiang L, Liu C, et al. Fibrous dysplasia of the mobile spine:report of 8 cases and review of the literature[J]. Spine (Phila Pa 1976), 2013, 38(23):2016-2022.
11.	Kotil K, Ozyuvaci E. Fibrous dysplasia in axis treated with vertebroplasty[J]. J Craniovertebr Junction Spine, 2010, 1(2):118-121.
12.	陳廣東, 楊惠林.微創治療胸椎骨纖維結構不良1例[J].中國矯形外科雜志, 2010, 18(15):1318-1319.
13.	吳奉梁, 姜亮, 楊邵敏, 等.脊柱多骨型纖維異常增殖癥的治療[J].北京大學學報:醫學版, 2013, 45(6):950-955.
14.	Christoforidis G, Dang D, Gabriel J. Catheter-directed percutaneous transpedicular C2/C3 vertebroplasty in a patient with fibrous dysplasia using seldinger technique[J]. AJNR Am J Neuroradiol, 2006, 27(8):1738-1740.
15.	Dang D, Baig MN, Christoforidis G, et al. C2/C3 pathologic fractures from polyostotic fibrous dysplasia of the cervical spine treated with percutaneous vertebroplasty[J]. Eur Spine J, 2007, 16(Suppl 3):250-254.
16.	Chen G, Yang H, Gan M, et al. Polyostotic fibrous dysplasia of the thoracic spine:case report and review of the literature[J]. Spine (Phila Pa 1976), 2011, 36(22):E1485-E1488.
17.	Deen HG, Fox TP. Balloon kyphoplasty for vertebral compression fractures secondary to polyostotic fibrous dysplasia. Case report[J]. J Neurosurg Spine, 2005, 3(3):234-237.
18.	Hatzitolios A, Savopoulos CH, Karagianopoulou G, et al. Pain and osteolysis of the thoracic spine——a case of a rare monostotic fibrous dysplasia manifestation[J]. Hippokratia, 2008, 12(4):254-256.
19.	Chapurlat RD. Medical therapy in adults with fibrous dysplasia of bone[J]. J Bone Miner Res, 2006, 21(Suppl 2):P114-P119.
20.	Chapurlat R. Current pharmacological treatment for fibrous dysplasia and perspectives for the future[J]. Joint Bone Spine, 2005, 72(3):196-198.
21.	Boyce AM, Kelly MH, Brillante BA, et al. A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone[J]. J Clin Endocrinol Metab, 2014, 99(11):4133-4140.
22.	Corsi A, Collins MT, Riminucci M, et al. Osteomalacic and hyperparathyroid changes in fibrous dysplasia of bone:core biopsy studies and clinical correlations[J]. J Bone Miner Res, 2003, 18(7):1235-1246.
23.	劉勇, 陳亮, 顧勇, 等.骶骨骨纖維結構不良一例報告[J].中國修復重建外科雜志, 2011, 25(2):148.
24.	常紅星, 朱兵, 姚建華, 等.第三腰椎骨纖維結構不良一例報告[J].中國骨腫瘤骨病, 2011, 10(1):92-94.
25.	胡星新, 劉立岷.單發型胸椎骨纖維性結構不良一例報告[J].中國修復重建外科雜志, 2014, 28(12):57.
26.	房根強, 張慶勝, 靳憲輝, 等.胸12及左側肋骨骨纖維異常增殖癥1例[J].中國腫瘤臨床, 2013, 40(10):615.
27.	Wu ZS, Hwang SL. Fibrous dysplasia of the thoracic spine[J]. Formosan J Surg, 2014, 47(3):122-126.
28.	Wu FL, Liu ZJ, Liu XG, et al. Polyostotic fibrous dysplasia involving the thoracic spine with myelopathy:case report and review of the literature[J]. Spine J, 2014, 14(1):e11-e15.
29.	Kim GT, Lee JK, Choi BJ, et al. Malignant transformation of monostotic fibrous dysplasia in the mandible[J]. J Craniofac Surg, 2010, 21(2):601-603.
30.	Yalniz E, Er T, Ozyilmaz F. Fibrous dysplasia of the spine with sarcomatous transformation:a case report and review of the literature[J]. Eur Spine J, 1995, 4(6):372-374.
31.	Fu CJ, Hsu CY, Shih TT, et al. Monostotic fibrous dysplasia of the thoracic spine with malignant transformation[J]. J Formos Med Assoc, 2004, 103(9):711-714.
32.	Rodenberg J, Jensen OM, Keller J, et al. Fibrous dysplasia of the spine, costae and hemipelvis with sarcomatous transformation[J]. Skeletal Radiol, 1996, 25(7):682-684.

1. Park SK, Lee IS, Choi JY, et al. CT and MRI of fibrous dysplasia of the spine[J]. Br J Radiol, 2012, 85(1015):996-1001.
2. 周幸, 吳蘇稼, 施鑫. T-5椎體骨纖維結構不良1例報告[J].中國矯形外科雜志, 2011, 19(9):717.
3. Harris WH, Dudley HR, Barry RJ. The natural history of fibrous dysplasia. An orthopaedic, pathological, and roentgenographic study[J]. J Bone Joint Surg Am, 1962, 44-A:207-233.
4. Proschek D, Orler R, Stauffer E, et al. Monostotic fibrous dysplasia of the spine:report of a case involving a cervical vertebra[J]. Arch Orthop Trauma Surg, 2007, 127(2):75-79.
5. Gogia N, Marwaha V, Atri S, et al. Fibrous dysplasia localized to spine:a diagnostic dilemma[J]. Skeletal Radiol, 2007, 36(Suppl 1):S19-S23.
6. Leet AI, Magur E, Lee JS, et al. Fibrous dysplasia in the spine:prevalence of lesions and association with scoliosis[J]. J Bone Joint Surg Am, 2004, 86-A(3):531-537.
7. Narayan RL, Maldjian PD. Restrictive lung disease and cor pulmonale secondary to polyostotic fibrous dysplasia[J]. Int J Cardiol, 2009, 131(2):e48-e50.
8. Yang C, Zhu B, Chen A. Imaging diagnosis of monostotic fibrous dysplasia in thoracic and lumbar spine vertebrae[J]. J Huazhong Univ Sci Technolog Med Sci, 2007, 27(6):684-686.
9. 李杰, 呂梁.脊椎骨纖維異常增殖癥的CT診斷[J].中國臨床醫學影像雜志, 2009, 20(5):316-318.
10. Wu FL, Jiang L, Liu C, et al. Fibrous dysplasia of the mobile spine:report of 8 cases and review of the literature[J]. Spine (Phila Pa 1976), 2013, 38(23):2016-2022.
11. Kotil K, Ozyuvaci E. Fibrous dysplasia in axis treated with vertebroplasty[J]. J Craniovertebr Junction Spine, 2010, 1(2):118-121.
12. 陳廣東, 楊惠林.微創治療胸椎骨纖維結構不良1例[J].中國矯形外科雜志, 2010, 18(15):1318-1319.
13. 吳奉梁, 姜亮, 楊邵敏, 等.脊柱多骨型纖維異常增殖癥的治療[J].北京大學學報:醫學版, 2013, 45(6):950-955.
14. Christoforidis G, Dang D, Gabriel J. Catheter-directed percutaneous transpedicular C2/C3 vertebroplasty in a patient with fibrous dysplasia using seldinger technique[J]. AJNR Am J Neuroradiol, 2006, 27(8):1738-1740.
15. Dang D, Baig MN, Christoforidis G, et al. C2/C3 pathologic fractures from polyostotic fibrous dysplasia of the cervical spine treated with percutaneous vertebroplasty[J]. Eur Spine J, 2007, 16(Suppl 3):250-254.
16. Chen G, Yang H, Gan M, et al. Polyostotic fibrous dysplasia of the thoracic spine:case report and review of the literature[J]. Spine (Phila Pa 1976), 2011, 36(22):E1485-E1488.
17. Deen HG, Fox TP. Balloon kyphoplasty for vertebral compression fractures secondary to polyostotic fibrous dysplasia. Case report[J]. J Neurosurg Spine, 2005, 3(3):234-237.
18. Hatzitolios A, Savopoulos CH, Karagianopoulou G, et al. Pain and osteolysis of the thoracic spine——a case of a rare monostotic fibrous dysplasia manifestation[J]. Hippokratia, 2008, 12(4):254-256.
19. Chapurlat RD. Medical therapy in adults with fibrous dysplasia of bone[J]. J Bone Miner Res, 2006, 21(Suppl 2):P114-P119.
20. Chapurlat R. Current pharmacological treatment for fibrous dysplasia and perspectives for the future[J]. Joint Bone Spine, 2005, 72(3):196-198.
21. Boyce AM, Kelly MH, Brillante BA, et al. A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone[J]. J Clin Endocrinol Metab, 2014, 99(11):4133-4140.
22. Corsi A, Collins MT, Riminucci M, et al. Osteomalacic and hyperparathyroid changes in fibrous dysplasia of bone:core biopsy studies and clinical correlations[J]. J Bone Miner Res, 2003, 18(7):1235-1246.
23. 劉勇, 陳亮, 顧勇, 等.骶骨骨纖維結構不良一例報告[J].中國修復重建外科雜志, 2011, 25(2):148.
24. 常紅星, 朱兵, 姚建華, 等.第三腰椎骨纖維結構不良一例報告[J].中國骨腫瘤骨病, 2011, 10(1):92-94.
25. 胡星新, 劉立岷.單發型胸椎骨纖維性結構不良一例報告[J].中國修復重建外科雜志, 2014, 28(12):57.
26. 房根強, 張慶勝, 靳憲輝, 等.胸12及左側肋骨骨纖維異常增殖癥1例[J].中國腫瘤臨床, 2013, 40(10):615.
27. Wu ZS, Hwang SL. Fibrous dysplasia of the thoracic spine[J]. Formosan J Surg, 2014, 47(3):122-126.
28. Wu FL, Liu ZJ, Liu XG, et al. Polyostotic fibrous dysplasia involving the thoracic spine with myelopathy:case report and review of the literature[J]. Spine J, 2014, 14(1):e11-e15.
29. Kim GT, Lee JK, Choi BJ, et al. Malignant transformation of monostotic fibrous dysplasia in the mandible[J]. J Craniofac Surg, 2010, 21(2):601-603.
30. Yalniz E, Er T, Ozyilmaz F. Fibrous dysplasia of the spine with sarcomatous transformation:a case report and review of the literature[J]. Eur Spine J, 1995, 4(6):372-374.
31. Fu CJ, Hsu CY, Shih TT, et al. Monostotic fibrous dysplasia of the thoracic spine with malignant transformation[J]. J Formos Med Assoc, 2004, 103(9):711-714.
32. Rodenberg J, Jensen OM, Keller J, et al. Fibrous dysplasia of the spine, costae and hemipelvis with sarcomatous transformation[J]. Skeletal Radiol, 1996, 25(7):682-684.

Previous Article
細胞程序性壞死的研究進展
Next Article
腋窩逆行淋巴顯影在乳腺癌手術中的應用

West China Medical Journal

脊柱骨纖維結構不良的診斷和治療研究進展

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content