Clinical Effects of Two Different Autolytic Debridement on Subcutaneous Wounds_West China Medical Journal

Authors：

 DaiYongjing ¹ ,  FengWei ² , LiHongju ¹ , LiMiaomiao ¹ , ZhangMingxue ³

1. Orthopedic Rehabilitation Ward;General Hospital of PLA, Beijing 100853, P. R. China;
2. Oncology Center;General Hospital of PLA, Beijing 100853, P. R. China;
3. Nursing Department;General Hospital of PLA, Beijing 100853, P. R. China;

Corresponding?author：

FengWei, Email: fengwei301@hotmail.com

Keywords：

Autolytic debridement; Subcutaneous tissue; Wound

DOI：

10.7507/1002-0179.201600406

Video：

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Objective To evaluate the effects of two different autolytic debridment on subcutaneous wounds. Methods Thirty-eight patients with subcutaneous wounds treated from January to December 2015 were numbered according to the sequence of admission, and were randomly divided into trial group and control group, with 19 patients in each group. All the patients had yellow surface. Patients in the control group were treated with amorphous hydrogel, while those in the trial group were treated with both amorphous hydrogel and alginate dressing. Then, we compared the two groups in terms of the debridement time, frequency of changing dressing, granulation growth, wound contraction rate at the end of debridement period, and leakage rate. Results The debridement time in the trial group was (21.11±5.86) days, and it was significantly shorter than that in the control group[(26.69±9.68) days] (P<0.05); the frequency of changing dressing was (7.21±2.12) times, which was less than that in the control group[(9.37±3.32) times] (P<0.05); and granulation growth was better than that in the control group (2.58±0.61 vs. 1.95±0.71, P<0.05). The wound contraction rate at the end of debridement period in the trial group was (47.00±26.24)%, which was higher than that in the control group[(29.03±22.62)%] (P<0.05); and the leakage rate (0.0%) was lower than the control group (3.3%) (P<0.05). Conclusion Using amorphous hydrogel and alginate dressing for subcutaneous wounds is better than amorphous hydrogel alone for autolytic debridement, and can lower the leakage rate.

Citation： DaiYongjing, FengWei, LiHongju, LiMiaomiao, ZhangMingxue. Clinical Effects of Two Different Autolytic Debridement on Subcutaneous Wounds. West China Medical Journal, 2016, 31(9): 1488-1491. doi: 10.7507/1002-0179.201600406 Copy

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1. 蔣琪霞, 李曉華. 清創方法及其關鍵技術的研究進展[J]. 中華護理雜志, 2009, 44(11):1045-1047.
2. 鄧曉琴, 彭李華, 何斌, 等. 創面床準備理論在慢性傷口中的應用研究[J]. 現代醫藥衛生, 2016, 32(9):1373-1375.
3. 闕華發. 創面床準備理論與糖尿病性足潰瘍的中醫干預策略[J]. 中國中西醫結合外科雜志, 2013, 19(3):346-348.
4. 呂娟, 寧寧, 葉霞, 等. 臨床實施醫護一體化傷口治療模式[J]. 華西醫學, 2012, 27(5):741-743.
5. 左建榮, 廖燈彬, 朱紅, 等. 骨科醫護一體化傷口管理成效[J]. 華西醫學, 2013, 28(9):1448-1450.
6. Winter GD. Formation of the scab and the rate of epithelization of superficial wounds in the skin of young domestic pig[J]. Nature, 1962, 193(8):293-294.
7. 陳冰, 羅娜, 孫偉龍, 等. 10%氯化鈉在Ⅲ期壓瘡清創期的應用研究[J]. 華西醫學, 2015, 30(10):1818-1820.
8. 蔣琪霞, 徐格林, 劉新峰. 神經內科患者壓瘡不同清創方法的效果[J]. 中華護理雜志, 2009, 44(3):197-200.
9. 梁明娟, 林瑞燕, 區詠儀. 自溶性清創結合外科清創處理乳腺癌術后胸壁皮瓣壞死的臨床實踐[J]. 嶺南現代臨床外科, 2011, 11(5):392.
10. Brett DW. A review of moisture-control dressings in wound care[J]. J Wound Ostomy Continence Nurs, 2006, 33(6, S):S3-S8.
11. Eriksson E, Vranckx J. Wet wound healing:from laboratory to patients to gene therapy[J]. Am J Surg, 2004, 188(1A, S):36S-41S.
12. Field FK, Kerstein MD. Overview of wound healing in moist environment[J]. Am J Surg, 1994, 167(1A):2S-6S.
13. Vogt PM, Andree C, Breuing K, et al. Dry, moist, and wet skin wound repair[J]. Ann Plast Surg, 1995, 34(5):493-500.
14. 朱守林. 濕性療法在慢性傷口處理中的應用觀察[J]. 實用臨床醫藥雜志, 2010, 14(6):67-69.
15. 劉冰, 葉蘭萍. 水凝膠敷料聯合復方紫草油在Ⅱ度燒傷創面中的應用[J]. 中國美容醫學, 2014, 23(16):1332.
16. 葛小靜, 章宏偉, 史京萍, 等. 藻酸鹽銀聯合水凝膠敷料對慢性創面愈合的作用[J]. 中國組織工程研究, 2012, 16(3):539-542.

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