Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital_West China Medical Journal

Authors：

LEI Xibing , HUANG Wei ,  CHEN Liping , TANG Yan , SUN Rui , TAN Muyang , XIAO Yaxiong

Nosocomial Infection Management Office, the First People’s Hospital of Yibin City, Yibin, Sichuan 644000, P. R. China;

Corresponding?author：

CHEN Liping, Email: 1837639492@qq.com

Keywords：

Multidrug resistance; Detection rate; Distribution

DOI：

10.7507/1002-0179.201702115

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the detection of multidrug-resistant organisms (MDRO) by targeted monitoring in a tertiary hospital, and to understand the distribution of MDRO. Methods We retrospectively analyzed the detection and distribution of methicillin-resistantStaphylococcus aureus (MRSA), carbon black alkeneAcinetobacter baumannii (CRABA), carbapenem-resistantPseudomonas aeruginosa (CRPAE), vancomycin-resistantEnterococci (VRE) and carbapenem-resistantEnterobacter (CRE) in clinical samples collected from 2013 to 2015. Results A total of 990 multidrug-resistant bacteria strains were isolated from 2013 to 2015, of which 445 were MRSA (44.95%), 328 were CRABA (33.13%), 99 were CRPAE (10.00%), 12 were VRE (1.21%), and 106 were CRE (10.71%). They were mainly distributed in the Department of Burn, Comprehensive ICU, Department of Neurosurgery, Department of Respiratory Medicine and Department of Orthopedic Surgery. The detection rates of multidrug-resistant organisms of 2013-2015 were 10.85% (352/3 244), 9.20% (304/3 303), and 7.11% (334/4 699) respectively, which reduced year by year with significant difference (χ²= 34.42,P< 0.001). The detection rates of CRPAE, CRE and VRE all reduced with significant differences (P< 0.05). Conclusions The detection rate of multidrug-resistant organisms under targeted monitoring shows an obvious downward trend. MRSA and CRABA are still the major MDROs, which show no obvious change. The detection rates of CRPAE, VRE and CRE show obvious downward trend. Department of Burn, Comprehensive ICU, Department of Neurosurgery, Department of Respiratory Medicine and Department of Orthopedic Surgery have the highest risks of MDRO. In the future, we should strengthen the monitoring of high-risk departments, and focus on the reasonable choice of special antimicrobial agents to avoid special MDROs.

Citation： LEI Xibing, HUANG Wei, CHEN Liping, TANG Yan, SUN Rui, TAN Muyang, XIAO Yaxiong. Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital. West China Medical Journal, 2017, 32(3): 334-338. doi: 10.7507/1002-0179.201702115 Copy

1.	?熊亞南, 劉穎. 細菌耐藥現狀及抗菌藥物研究進展. 中華醫學信息導報, 2016, 31(8): 16.
2.	張禹. 合理使用抗生素刻不容緩. 家庭醫藥, 2016(4): 40-41.
3.	陳家敏, 李新. 某院 2013 年院內感染臨床耐藥情況的監測報告. 中國醫藥指南, 2014(36): 376-378.
4.	張雅薇, 王輝. 2015 年 CLSI M100-S25 主要更新內容介紹. 中華檢驗醫學雜志, 2015, 38(4): 229-232.
5.	張靜, 喻瑋, 趙麗娜, 等. 我國細菌耐藥現狀與特征. 中華臨床感染病雜志, 2016, 9(2): 118-128.
6.	王曉川, 郝雪龔, 大潔. “超級細菌”簡介. 生物學教學, 2016, 41(9): 58-58, 59.
7.	Pal C, Bengtsson-Palme J, Kristiansson E,et al. The structure and diversity of human, animal and environmental resistomes. Microbiome, 2016, 4(1): 54.
8.	王金榮, 高攀, 崔朝勃, 等. 某院重癥醫學科 2010–2013 年鮑曼不動桿菌耐藥性監測. 中國感染控制雜志, 2016, 15(2): 108-110.
9.	孫吉花, 張學美, 邢敏, 等. 山東省多中心 ICU 多藥耐藥菌目標性監測分析. 中華醫院感染學雜志, 2016, 26(11): 2465-2467, 2616.
10.	陳曉娟, 任琳潔, 黃建瓊. 根因分析在燒傷層流病房多重耐藥菌管理中的應用. 華西醫學, 2016, 31(8): 1413-1415.
11.	陳佰義, 何禮賢, 胡必杰, 等. 中國鮑曼不動桿菌感染診治與防控專家共識. 中國醫藥科學, 2012, 2(8): 3-8.
12.	雷曦兵, 陳麗萍, 肖亞雄. 某三級甲等醫院實施多重耐藥防控干預效果研究. 華西醫學, 2016, 31(3): 409-413.
13.	李露池, 沈暉. 某三級綜合醫院多重耐藥菌臨床分布. 中國感染控制雜志, 2014, 13(4): 242-245.
14.	王盟. 2012 至 2014 年某三級綜合醫院住院患者多藥耐藥菌感染分析. 中華實驗和臨床感染病雜志: 電子版, 2016, 10(3): 333-336.
15.	國家衛生計生委合理用藥專家委員會, 全國細菌耐藥監測網. 2015 年全國細菌耐藥監測報告. 中國執業藥師, 2016, 3(13): 3-8.
16.	李耘, 呂媛, 薛峰, 等. 中國細菌耐藥監測研究 2013 至 2014 年非發酵革蘭陰性菌監測報告. 中華檢驗醫學雜志, 2016, 39(2): 130-138.

1. ?熊亞南, 劉穎. 細菌耐藥現狀及抗菌藥物研究進展. 中華醫學信息導報, 2016, 31(8): 16.
2. 張禹. 合理使用抗生素刻不容緩. 家庭醫藥, 2016(4): 40-41.
3. 陳家敏, 李新. 某院 2013 年院內感染臨床耐藥情況的監測報告. 中國醫藥指南, 2014(36): 376-378.
4. 張雅薇, 王輝. 2015 年 CLSI M100-S25 主要更新內容介紹. 中華檢驗醫學雜志, 2015, 38(4): 229-232.
5. 張靜, 喻瑋, 趙麗娜, 等. 我國細菌耐藥現狀與特征. 中華臨床感染病雜志, 2016, 9(2): 118-128.
6. 王曉川, 郝雪龔, 大潔. “超級細菌”簡介. 生物學教學, 2016, 41(9): 58-58, 59.
7. Pal C, Bengtsson-Palme J, Kristiansson E,et al. The structure and diversity of human, animal and environmental resistomes. Microbiome, 2016, 4(1): 54.
8. 王金榮, 高攀, 崔朝勃, 等. 某院重癥醫學科 2010–2013 年鮑曼不動桿菌耐藥性監測. 中國感染控制雜志, 2016, 15(2): 108-110.
9. 孫吉花, 張學美, 邢敏, 等. 山東省多中心 ICU 多藥耐藥菌目標性監測分析. 中華醫院感染學雜志, 2016, 26(11): 2465-2467, 2616.
10. 陳曉娟, 任琳潔, 黃建瓊. 根因分析在燒傷層流病房多重耐藥菌管理中的應用. 華西醫學, 2016, 31(8): 1413-1415.
11. 陳佰義, 何禮賢, 胡必杰, 等. 中國鮑曼不動桿菌感染診治與防控專家共識. 中國醫藥科學, 2012, 2(8): 3-8.
12. 雷曦兵, 陳麗萍, 肖亞雄. 某三級甲等醫院實施多重耐藥防控干預效果研究. 華西醫學, 2016, 31(3): 409-413.
13. 李露池, 沈暉. 某三級綜合醫院多重耐藥菌臨床分布. 中國感染控制雜志, 2014, 13(4): 242-245.
14. 王盟. 2012 至 2014 年某三級綜合醫院住院患者多藥耐藥菌感染分析. 中華實驗和臨床感染病雜志: 電子版, 2016, 10(3): 333-336.
15. 國家衛生計生委合理用藥專家委員會, 全國細菌耐藥監測網. 2015 年全國細菌耐藥監測報告. 中國執業藥師, 2016, 3(13): 3-8.
16. 李耘, 呂媛, 薛峰, 等. 中國細菌耐藥監測研究 2013 至 2014 年非發酵革蘭陰性菌監測報告. 中華檢驗醫學雜志, 2016, 39(2): 130-138.

West China Medical Journal

Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content