Application of rehabilitation training in lung cancer patients during chemotherapy_West China Medical Journal

Authors：

CONG Qirui ¹ ,  NI Jun ²

1. Department of Rehabilitation Medicine, Danyang People’s Hospital, Danyang, Jiangsu 212300, P. R. China;
2. Department of Rehabilitation Medicine, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, P. R. China;

Corresponding?author：

NI Jun, Email: nijun1000@126.com

Keywords：

Lung cancer; chemotherapy; rehabilitation

DOI：

10.7507/1002-0179.202106137

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

The global incidence of lung cancer ranks second among cancers, which has caused a serious burden on patients’ family and society. Chemotherapy is a common treatment for lung cancer, which often leads to a decrease in patients’ physical function and quality of life. Pulmonary rehabilitation during perioperative period of lung cancer has received extensive attention, but pulmonary rehabilitation during chemotherapy of lung cancer has not been paid much attention. This article reviews the role of rehabilitation during chemotherapy for lung cancer, and focuses on the role of rehabilitation during chemotherapy for lung cancer patients with different treatment programs. The purpose is to promote the research and promotion of rehabilitation training in lung cancer patients receiving chemotherapy, so as to further improve patients’ function and quality of life.

Citation： CONG Qirui, NI Jun. Application of rehabilitation training in lung cancer patients during chemotherapy. West China Medical Journal, 2022, 37(1): 12-16. doi: 10.7507/1002-0179.202106137 Copy

1.	Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021, 71(3): 209-249.
2.	鄭榮壽, 孫可欣, 張思維, 等. 2015年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2019, 41(1): 19-28.
3.	Molina JR, Yang P, Cassivi SD, et al. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc, 2008, 83(5): 584-594.
4.	Lakoski SG, Eves ND, Douglas PS, et al. Exercise rehabilitation in patients with cancer. Nat Rev Clin Oncol, 2012, 9(5): 288-296.
5.	Spruit MA, Janssen PP, Willemsen SC, et al. Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study. Lung Cancer, 2006, 52(2): 257-260.
6.	Hanna N, Neubauer M, Yiannoutsos C, et al. Phase Ⅲ study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage Ⅲ non-small-cell lung cancer: the Hoosier Oncology Group and U. S. Oncology. J Clin Oncol, 2008, 26(35): 5755-5760.
7.	Giese-Davis J, Collie K, Rancourt KM, et al. Decrease in depression symptoms is associated with longer survival in patients with metastatic breast cancer: a secondary analysis. J Clin Oncol, 2011, 29(4): 413-420.
8.	Clouston SAP, Rubin MS, Chae DH, et al. Fundamental causes of accelerated declines in colorectal cancer mortality: modeling multiple ways that disadvantage influences mortality risk. Soc Sci Med, 2017, 187: 1-10.
9.	臧瑜, 于虹, 李妍, 等. 肺癌患者癥狀群的調查研究. 中華護理雜志, 2016, 51(3): 316-320.
10.	Lee J. Physiologic and psychologic adaptation to exercise interventions in lung cancer patients undergoing chemotherapy: a systematic review and meta-analysis of randomized controlled trials. Support Care Cancer, 2021, 29(6): 2863-2873.
11.	Chasen MR, Dippenaar AP. Cancer nutrition and rehabilitation-its time has come!. Curr Oncol, 2008, 15(3): 117-122.
12.	Campbell KL, Winters-Stone KM, Wiskemann J, et al. Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable. Med Sci Sports Exerc, 2019, 51(11): 2375-2390.
13.	Schmitz KH, Courneya KS, Matthews C, et al. American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc, 2010, 42(7): 1409-1426.
14.	Knols R, Aaronson NK, Uebelhart D, et al. Physical exercise in cancer patients during and after medical treatment: a systematic review of randomized and controlled clinical trials. J Clin Oncol, 2005, 23(16): 3830-3842.
15.	Spruit MA, Singh SJ, Garvey C, et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med, 2013, 188(8): e13-e64.
16.	Edbrooke L, Aranda S, Granger CL, et al. Benefits of home-based multidisciplinary exercise and supportive care in inoperable non-small cell lung cancer - protocol for a phase Ⅱ randomised controlled trial. BMC Cancer, 2017, 17(1): 663.
17.	Hoffman AJ, Brintnall RA, von Eye A, et al. Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients. J Thorac Dis, 2014, 6(6): 632-640.
18.	Rock CL, Doyle C, Demark-Wahnefried W, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin, 2012, 62(4): 243-274.
19.	董倩, 林洪生. 從國外癌癥康復現狀論中醫藥在癌癥康復中的應用與挑戰. 世界中醫藥, 2014, 9(7): 857-863.
20.	Wesa K, Gubili J, Cassileth B. Integrative oncology: complementary therapies for cancer survivors. Hematol Oncol Clin North Am, 2008, 22(2): 343-353, viii.
21.	韓睿, 林洪生. 健身氣功八段錦對非小細胞肺癌術后患者肺功能及生存質量干預療效的臨床研究. 天津中醫藥, 2016, 33(12): 715-718.
22.	劉秀英, 潘孟俠, 夏立偉. 應用中醫音樂療法治療肺癌患者術后不良情緒的效果及護理. 時珍國醫國藥, 2013, 24(1): 216-217.
23.	楊術蘭, 何燕, 王丹. 肺癌術后化療患者的中醫飲食護理研究. 時珍國醫國藥, 2018, 29(2): 386-387.
24.	彭博, 黃雨滟, 黃厚強, 等. 術后肺康復訓練對肺癌患者影響的系統評價及meta分析. 現代醫藥衛生, 2021, 37(22): 3836-3841, 3880.
25.	陳瑞英, 劉雅, 孫婷, 等. 肺康復運動訓練對肺癌患者呼吸運動功能、生活質量及總生存期的影響. 中華物理醫學與康復雜志, 2019(1): 31-36.
26.	趙磊, 周媛媛. 術前呼吸功能鍛煉聯合術后強化式呼吸道在老年肺癌胸腔鏡術后康復中的效果. 新疆醫學, 2021, 51(11): 1280-1283.
27.	Shi JF, Wang L, Wu N, et al. Clinical characteristics and medical service utilization of lung cancer in China, 2005-2014: overall design and results from a multicenter retrospective epidemiologic survey. Lung Cancer, 2019, 128: 91-100.
28.	Granger CL. Physiotherapy management of lung cancer. J Physiother, 2016, 62(2): 60-67.
29.	Jastrz?bski D, Maksymiak M, Kostorz S, et al. Pulmonary rehabilitation in advanced lung cancer patients during chemotherapy. Adv Exp Med Biol, 2015, 861: 57-64.
30.	Quist M, Adamsen L, R?rth M, et al. The impact of a multidimensional exercise intervention on physical and functional capacity, anxiety, and depression in patients with advanced-stage lung cancer undergoing chemotherapy. Integr Cancer Ther, 2015, 14(4): 341-349.
31.	Rutkowska A, Jastrzebski D, Rutkowski S, et al. Exercise training in patients with non-small cell lung cancer during in-hospital chemotherapy treatment: a randomized controlled trial. J Cardiopulm Rehabil Prev, 2019, 39(2): 127-133.
32.	朱燁, 徐敏. 肺康復運動訓練對非手術肺癌患者呼吸運動功能、中長期生活質量、生存狀況及并發癥的影響分析. 實用心腦肺血管病雜志, 2021, 29(增刊 2): 67-69.
33.	Tao X, Yuan C, Zheng D, et al. Outcomes comparison between neoadjuvant chemotherapy and adjuvant chemotherapy in stage ⅢA non-small cell lung cancer patients. J Thorac Dis, 2019, 11(4): 1443-1455.
34.	Margaritora S, Cesario A, Cusumano G, et al. Is pulmonary function damaged by neoadjuvant lung cancer therapy? A comprehensive serial time-trend analysis of pulmonary function after induction radiochemotherapy plus surgery. J Thorac Cardiovasc Surg, 2010, 139(6): 1457-1463.
35.	Venuta F, Anile M, Diso D, et al. Operative complications and early mortality after induction therapy for lung cancer. Eur J Cardiothorac Surg, 2007, 31(4): 714-717.
36.	Tarumi S, Yokomise H, Gotoh M, et al. Pulmonary rehabilitation during induction chemoradiotherapy for lung cancer improves pulmonary function. J Thorac Cardiovasc Surg, 2015, 149(2): 569-573.
37.	朱文軍. 中醫非藥物療法對非小細胞肺癌術后康復患者生活質量的影響. 南京: 南京中醫藥大學, 2019: 1-62.
38.	Bezjak A, Lee CW, Ding K, et al. Quality-of-life outcomes for adjuvant chemotherapy in early-stage non-small-cell lung cancer: results from a randomized trial, JBR. 10. J Clin Oncol, 2008, 26(31): 5052-5059.
39.	Hickok JT, Roscoe JA, Morrow GR, et al. Frequency, severity, clinical course, and correlates of fatigue in 372 patients during 5 weeks of radiotherapy for cancer. Cancer, 2005, 104(8): 1772-1778.
40.	Phillips SM, McAuley E. Physical activity and fatigue in breast cancer survivors: a panel model examining the role of self-efficacy and depression. Cancer Epidemiol Biomarkers Prev, 2013, 22(5): 773-781.
41.	Mitchell SA, Hoffman AJ, Clark JC, et al. Putting evidence into practice: an update of evidence-based interventions for cancer-related fatigue during and following treatment. Clin J Oncol Nurs, 2014(Suppl 18): 38-58.
42.	Hoffman AJ, Brintnall RA, Brown JK, et al. Virtual reality bringing a new reality to postthoracotomy lung cancer patients via a home-based exercise intervention targeting fatigue while undergoing adjuvant treatment. Cancer Nurs, 2014, 37(1): 23-33.
43.	Hoffman AJ, Brintnall RA, Given BA, et al. Using perceived self-efficacy to improve fatigue and fatigability in postsurgical lung cancer patients: a pilot randomized controlled trial. Cancer Nurs, 2017, 40(1): 1-12.
44.	Hilfiker R, Meichtry A, Eicher M, et al. Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis. Br J Sports Med, 2018, 52(10): 651-658.
45.	Scott JM, Thomas SM, Herndon JE 2nd, et al. Effects and tolerability of exercise therapy modality on cardiorespiratory fitness in lung cancer: a randomized controlled trial. J Cachexia Sarcopenia Muscle, 2021, 12(6): 1456-1465.
46.	Brunelli A, Kim AW, Berger KI, et al. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 2013, 143(Suppl 5): e166S-e190S.
47.	Brunelli A, Belardinelli R, Refai M, et al. Peak oxygen consumption during cardiopulmonary exercise test improves risk stratification in candidates to major lung resection. Chest, 2009, 135(5): 1260-1267.
48.	Cavalheri V, Burtin C, Formico VR, et al. Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer. Cochrane Database Syst Rev, 2019, 6(6): CD009955.
49.	陳玉芬, 楊春茂, 李燕舞. 肺康復訓練對肺癌化療病人肺功能、癌因性疲乏及生活質量的影響. 蚌埠醫學院學報, 2019, 44(8): 1123-1126.
50.	張婷, 權美麗. 肺康復訓練對肺癌患者術后化療肺功能及生活質量的影響. 中國煤炭工業醫學雜志, 2016, 19(9): 1371-1374.
51.	葉靜, 謝國省. 家庭肺康復訓練對肺癌肺葉切除術后化療患者肺功能、癌因性疲乏和焦慮抑郁情緒的影響. 中國煤炭工業醫學雜志, 2019, 22(2): 220-224.
52.	張慧明. 肺康復訓練對肺癌術后化療患者生活質量的影響. 天津: 天津醫科大學, 2014: 1-54.
53.	孔輕輕. 肺康復訓練對肺癌術后化療患者生活質量及癌因性疲乏的影響. 天津: 天津醫科大學, 2014: 1-74.

1. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021, 71(3): 209-249.
2. 鄭榮壽, 孫可欣, 張思維, 等. 2015年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2019, 41(1): 19-28.
3. Molina JR, Yang P, Cassivi SD, et al. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc, 2008, 83(5): 584-594.
4. Lakoski SG, Eves ND, Douglas PS, et al. Exercise rehabilitation in patients with cancer. Nat Rev Clin Oncol, 2012, 9(5): 288-296.
5. Spruit MA, Janssen PP, Willemsen SC, et al. Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study. Lung Cancer, 2006, 52(2): 257-260.
6. Hanna N, Neubauer M, Yiannoutsos C, et al. Phase Ⅲ study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage Ⅲ non-small-cell lung cancer: the Hoosier Oncology Group and U. S. Oncology. J Clin Oncol, 2008, 26(35): 5755-5760.
7. Giese-Davis J, Collie K, Rancourt KM, et al. Decrease in depression symptoms is associated with longer survival in patients with metastatic breast cancer: a secondary analysis. J Clin Oncol, 2011, 29(4): 413-420.
8. Clouston SAP, Rubin MS, Chae DH, et al. Fundamental causes of accelerated declines in colorectal cancer mortality: modeling multiple ways that disadvantage influences mortality risk. Soc Sci Med, 2017, 187: 1-10.
9. 臧瑜, 于虹, 李妍, 等. 肺癌患者癥狀群的調查研究. 中華護理雜志, 2016, 51(3): 316-320.
10. Lee J. Physiologic and psychologic adaptation to exercise interventions in lung cancer patients undergoing chemotherapy: a systematic review and meta-analysis of randomized controlled trials. Support Care Cancer, 2021, 29(6): 2863-2873.
11. Chasen MR, Dippenaar AP. Cancer nutrition and rehabilitation-its time has come!. Curr Oncol, 2008, 15(3): 117-122.
12. Campbell KL, Winters-Stone KM, Wiskemann J, et al. Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable. Med Sci Sports Exerc, 2019, 51(11): 2375-2390.
13. Schmitz KH, Courneya KS, Matthews C, et al. American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc, 2010, 42(7): 1409-1426.
14. Knols R, Aaronson NK, Uebelhart D, et al. Physical exercise in cancer patients during and after medical treatment: a systematic review of randomized and controlled clinical trials. J Clin Oncol, 2005, 23(16): 3830-3842.
15. Spruit MA, Singh SJ, Garvey C, et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med, 2013, 188(8): e13-e64.
16. Edbrooke L, Aranda S, Granger CL, et al. Benefits of home-based multidisciplinary exercise and supportive care in inoperable non-small cell lung cancer - protocol for a phase Ⅱ randomised controlled trial. BMC Cancer, 2017, 17(1): 663.
17. Hoffman AJ, Brintnall RA, von Eye A, et al. Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients. J Thorac Dis, 2014, 6(6): 632-640.
18. Rock CL, Doyle C, Demark-Wahnefried W, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin, 2012, 62(4): 243-274.
19. 董倩, 林洪生. 從國外癌癥康復現狀論中醫藥在癌癥康復中的應用與挑戰. 世界中醫藥, 2014, 9(7): 857-863.
20. Wesa K, Gubili J, Cassileth B. Integrative oncology: complementary therapies for cancer survivors. Hematol Oncol Clin North Am, 2008, 22(2): 343-353, viii.
21. 韓睿, 林洪生. 健身氣功八段錦對非小細胞肺癌術后患者肺功能及生存質量干預療效的臨床研究. 天津中醫藥, 2016, 33(12): 715-718.
22. 劉秀英, 潘孟俠, 夏立偉. 應用中醫音樂療法治療肺癌患者術后不良情緒的效果及護理. 時珍國醫國藥, 2013, 24(1): 216-217.
23. 楊術蘭, 何燕, 王丹. 肺癌術后化療患者的中醫飲食護理研究. 時珍國醫國藥, 2018, 29(2): 386-387.
24. 彭博, 黃雨滟, 黃厚強, 等. 術后肺康復訓練對肺癌患者影響的系統評價及meta分析. 現代醫藥衛生, 2021, 37(22): 3836-3841, 3880.
25. 陳瑞英, 劉雅, 孫婷, 等. 肺康復運動訓練對肺癌患者呼吸運動功能、生活質量及總生存期的影響. 中華物理醫學與康復雜志, 2019(1): 31-36.
26. 趙磊, 周媛媛. 術前呼吸功能鍛煉聯合術后強化式呼吸道在老年肺癌胸腔鏡術后康復中的效果. 新疆醫學, 2021, 51(11): 1280-1283.
27. Shi JF, Wang L, Wu N, et al. Clinical characteristics and medical service utilization of lung cancer in China, 2005-2014: overall design and results from a multicenter retrospective epidemiologic survey. Lung Cancer, 2019, 128: 91-100.
28. Granger CL. Physiotherapy management of lung cancer. J Physiother, 2016, 62(2): 60-67.
29. Jastrz?bski D, Maksymiak M, Kostorz S, et al. Pulmonary rehabilitation in advanced lung cancer patients during chemotherapy. Adv Exp Med Biol, 2015, 861: 57-64.
30. Quist M, Adamsen L, R?rth M, et al. The impact of a multidimensional exercise intervention on physical and functional capacity, anxiety, and depression in patients with advanced-stage lung cancer undergoing chemotherapy. Integr Cancer Ther, 2015, 14(4): 341-349.
31. Rutkowska A, Jastrzebski D, Rutkowski S, et al. Exercise training in patients with non-small cell lung cancer during in-hospital chemotherapy treatment: a randomized controlled trial. J Cardiopulm Rehabil Prev, 2019, 39(2): 127-133.
32. 朱燁, 徐敏. 肺康復運動訓練對非手術肺癌患者呼吸運動功能、中長期生活質量、生存狀況及并發癥的影響分析. 實用心腦肺血管病雜志, 2021, 29(增刊 2): 67-69.
33. Tao X, Yuan C, Zheng D, et al. Outcomes comparison between neoadjuvant chemotherapy and adjuvant chemotherapy in stage ⅢA non-small cell lung cancer patients. J Thorac Dis, 2019, 11(4): 1443-1455.
34. Margaritora S, Cesario A, Cusumano G, et al. Is pulmonary function damaged by neoadjuvant lung cancer therapy? A comprehensive serial time-trend analysis of pulmonary function after induction radiochemotherapy plus surgery. J Thorac Cardiovasc Surg, 2010, 139(6): 1457-1463.
35. Venuta F, Anile M, Diso D, et al. Operative complications and early mortality after induction therapy for lung cancer. Eur J Cardiothorac Surg, 2007, 31(4): 714-717.
36. Tarumi S, Yokomise H, Gotoh M, et al. Pulmonary rehabilitation during induction chemoradiotherapy for lung cancer improves pulmonary function. J Thorac Cardiovasc Surg, 2015, 149(2): 569-573.
37. 朱文軍. 中醫非藥物療法對非小細胞肺癌術后康復患者生活質量的影響. 南京: 南京中醫藥大學, 2019: 1-62.
38. Bezjak A, Lee CW, Ding K, et al. Quality-of-life outcomes for adjuvant chemotherapy in early-stage non-small-cell lung cancer: results from a randomized trial, JBR. 10. J Clin Oncol, 2008, 26(31): 5052-5059.
39. Hickok JT, Roscoe JA, Morrow GR, et al. Frequency, severity, clinical course, and correlates of fatigue in 372 patients during 5 weeks of radiotherapy for cancer. Cancer, 2005, 104(8): 1772-1778.
40. Phillips SM, McAuley E. Physical activity and fatigue in breast cancer survivors: a panel model examining the role of self-efficacy and depression. Cancer Epidemiol Biomarkers Prev, 2013, 22(5): 773-781.
41. Mitchell SA, Hoffman AJ, Clark JC, et al. Putting evidence into practice: an update of evidence-based interventions for cancer-related fatigue during and following treatment. Clin J Oncol Nurs, 2014(Suppl 18): 38-58.
42. Hoffman AJ, Brintnall RA, Brown JK, et al. Virtual reality bringing a new reality to postthoracotomy lung cancer patients via a home-based exercise intervention targeting fatigue while undergoing adjuvant treatment. Cancer Nurs, 2014, 37(1): 23-33.
43. Hoffman AJ, Brintnall RA, Given BA, et al. Using perceived self-efficacy to improve fatigue and fatigability in postsurgical lung cancer patients: a pilot randomized controlled trial. Cancer Nurs, 2017, 40(1): 1-12.
44. Hilfiker R, Meichtry A, Eicher M, et al. Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis. Br J Sports Med, 2018, 52(10): 651-658.
45. Scott JM, Thomas SM, Herndon JE 2nd, et al. Effects and tolerability of exercise therapy modality on cardiorespiratory fitness in lung cancer: a randomized controlled trial. J Cachexia Sarcopenia Muscle, 2021, 12(6): 1456-1465.
46. Brunelli A, Kim AW, Berger KI, et al. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 2013, 143(Suppl 5): e166S-e190S.
47. Brunelli A, Belardinelli R, Refai M, et al. Peak oxygen consumption during cardiopulmonary exercise test improves risk stratification in candidates to major lung resection. Chest, 2009, 135(5): 1260-1267.
48. Cavalheri V, Burtin C, Formico VR, et al. Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer. Cochrane Database Syst Rev, 2019, 6(6): CD009955.
49. 陳玉芬, 楊春茂, 李燕舞. 肺康復訓練對肺癌化療病人肺功能、癌因性疲乏及生活質量的影響. 蚌埠醫學院學報, 2019, 44(8): 1123-1126.
50. 張婷, 權美麗. 肺康復訓練對肺癌患者術后化療肺功能及生活質量的影響. 中國煤炭工業醫學雜志, 2016, 19(9): 1371-1374.
51. 葉靜, 謝國省. 家庭肺康復訓練對肺癌肺葉切除術后化療患者肺功能、癌因性疲乏和焦慮抑郁情緒的影響. 中國煤炭工業醫學雜志, 2019, 22(2): 220-224.
52. 張慧明. 肺康復訓練對肺癌術后化療患者生活質量的影響. 天津: 天津醫科大學, 2014: 1-54.
53. 孔輕輕. 肺康復訓練對肺癌術后化療患者生活質量及癌因性疲乏的影響. 天津: 天津醫科大學, 2014: 1-74.

Previous Article
Research progress on the relationship between obstructive sleep apnea hypopnea syndrome and metabolic syndrome
Next Article
Progress in the treatment of hyperlipidemia acute pancreatitis

West China Medical Journal

Application of rehabilitation training in lung cancer patients during chemotherapy

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content