Diagnosis and Surgical Treatment of Malignant Cardiac Tumors_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

LIUKai-yu ,  TIANHai , JIANGShu-lin

Department of Cardiovascular Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin 150086, P. R. China;

Corresponding?author：

TIANHai, Email: clownemail@163.com

Keywords：

Malignant cardiac tumor; Diagnosis; Surgery

DOI：

10.7507/1007-4848.20140131

Video：

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Objective To investigate clinical characteristics of patients with malignant cardiac tumors, and summarize our diagnostic methods and surgical treatment experience. Methods Clinical data of 16 patients with mali-gnant cardiac tumors who were admitted to Department of Cardiovascular Surgery, Second Affiliated Hospital of Harbin Medical University between January 2005 and February 2012 were retrospectively analyzed. There were 8 male and 8 female patients with their age of 35-64 (47.8±10.9) years and disease duration of 15 days to 48 months (11.8±10.9) months. Among the 16 patients, 13 patients underwent tumor resection under cardiopulmonary bypass (CPB), including 1 patient who received complete resection of the tumor and pedicle surrounding tissue and other 12 patients who only received partial tumor resection. One patient underwent concomitant tricuspid valve replacement. Results All the operations were performed successfully. One patient died of low cardiac output syndrome and multiple organ dysfunction syndrome on the 6th postoperative day. All the other patients were successfully discharged. Average operation time was 181.2±59.5 minutes, average CPB time was 68.8±20.8 minutes, and average length of hospital stay was 20.4±7.4 days. Postoperative pathological examination showed primary cardiac malignant tumors in 9 patients, metastatic malignant tumors in 6 patients, and benign tumor with malignant growth in 1 patient. Three patients were followed up for a short time (≥3 months) and were still alive. Nine patients died in 1-14 months after discharge. One patient with benign cardiac tumor but malignant growth was still alive. Conclusion Malignant cardiac tumors are rare but highly malignant with a high rate of misdiagnosis. Surgical outcomes are comparatively satisfactory, but these patients' prognosis is usually poor.

Citation： LIUKai-yu, TIANHai, JIANGShu-lin. Diagnosis and Surgical Treatment of Malignant Cardiac Tumors. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2014, 21(4): 461-464. doi: 10.7507/1007-4848.20140131 Copy

1.	王詠, 肖穎彬, 陳林, 等.心臟腫瘤181例外科治療的臨床分析.中國胸心血管外科臨床雜志, 2013, 20 (2):155-158.
2.	朱云喜, 胡建國, 周新民, 等.原發性心臟腫瘤138例的臨床診斷與外科治療.腫瘤, 2010, 30 (11):965-968.
3.	Miyake CY, Del Nido PJ, Alexander ME, et al. Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardio, 2011, 58 (18):1903-1909.
4.	Combes M, Rottey S, De Backer T. Cardiovascular toxicity of cancer treatment. Acta Clin Belg, 2011, 66 (4):260-266.
5.	宋書田, 周岊梧, 張彬, 等.原發性心臟惡性腫瘤的診斷與外科治療經驗.中國心血管雜志, 2008, 13 (4):268-270.
6.	Debourdeau P, Gligorov J, Teixeira L, et al. Malignant cardiac tumors. Bull Cancer, 2004, 91 (Suppl 3):136-146.
7.	Gopal AS, Stathopoulos JA, Arora N, et al. Differential diagnosis of intracavitary tumors obstructing the right ventricular outflow tract. J Am Soc Echocardiogr, 2001, 14 (9):937-940.
8.	Kubota H, Takamoto S, Kotsuka Y, et al. Surgical treatment of malignant tumours of the right heart. Jpn Heart J, 2002, 43 (3):263-271.
9.	鄧明彬, 廖斌, 李新, 等. 22例心臟腫瘤的診斷與治療.中國胸心血管外科臨床雜志, 2011, 18 (2):108.
10.	謝寶棟, 康凱, 張宇南, 等. 28例右心系統腫瘤的診斷與外科治療.中國胸心血管外科臨床雜志, 2007, 14 (4):306-307.
11.	劉莉, 宋秀珍, 謝德軒.多普勒超聲心動圖對心臟原發性腫瘤的應用研究.中國醫學影像技術, 2008, 24 (6):896-899.
12.	Bauner KU, Sourbron S, Picciolo M, et al. MR first pass perfusion of benign and malignant cardiac tumours-significant differences and diagnostic accuracy. Eur Radiol, 2012, 22 (1):73-82.
13.	李德強, 閻德民, 谷天祥, 等.右房粘液瘤的外科治療.中國醫科大學學報, 2001, 30 (2):156-157.
14.	Qin C, Chen L, Xiao YB, et al. Giant primary leiomyoma of the right ventricle. J Card Surg, 2010, 25 (2):169-1671.
15.	Karasu BB, Yeter E, Yilmazer D, et al. Primary valvular lipomatous hamartoma:a case report and a collective review of the literature. Cardiovasc Pathol, 2011, 20 (6):377-380.
16.	Yuan SM, Shinfeld A, Raanani E. Tricuspid valve myxoma:a case report and a collective review of the literature. J Card Surg, 2009, 24 (1):69-72.
17.	高志, 路天怡, 許建屏, 等.心臟惡性腫痛10例分析.北京大學學報:醫學版, 2003, 35 (3):333-334.
18.	張勇, 梁家立.心臟原發惡性腫瘤五例報告.中華腫瘤防治雜志, 2012, 19 (22):1751-1752.
19.	張玉海, 谷天祥, 王春, 等.累及心臟的靜脈內平滑肌瘤的診斷策略和外科治療.中國醫科大學學報, 2012, 41 (12):1148-1149.
20.	李旻, 潘凌亞, 連麗娟.伴有心臟受累的靜脈內平滑肌瘤病臨床分析.現代婦產科進展, 2006, 15 (3):191-194.

1. 王詠, 肖穎彬, 陳林, 等.心臟腫瘤181例外科治療的臨床分析.中國胸心血管外科臨床雜志, 2013, 20 (2):155-158.
2. 朱云喜, 胡建國, 周新民, 等.原發性心臟腫瘤138例的臨床診斷與外科治療.腫瘤, 2010, 30 (11):965-968.
3. Miyake CY, Del Nido PJ, Alexander ME, et al. Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardio, 2011, 58 (18):1903-1909.
4. Combes M, Rottey S, De Backer T. Cardiovascular toxicity of cancer treatment. Acta Clin Belg, 2011, 66 (4):260-266.
5. 宋書田, 周岊梧, 張彬, 等.原發性心臟惡性腫瘤的診斷與外科治療經驗.中國心血管雜志, 2008, 13 (4):268-270.
6. Debourdeau P, Gligorov J, Teixeira L, et al. Malignant cardiac tumors. Bull Cancer, 2004, 91 (Suppl 3):136-146.
7. Gopal AS, Stathopoulos JA, Arora N, et al. Differential diagnosis of intracavitary tumors obstructing the right ventricular outflow tract. J Am Soc Echocardiogr, 2001, 14 (9):937-940.
8. Kubota H, Takamoto S, Kotsuka Y, et al. Surgical treatment of malignant tumours of the right heart. Jpn Heart J, 2002, 43 (3):263-271.
9. 鄧明彬, 廖斌, 李新, 等. 22例心臟腫瘤的診斷與治療.中國胸心血管外科臨床雜志, 2011, 18 (2):108.
10. 謝寶棟, 康凱, 張宇南, 等. 28例右心系統腫瘤的診斷與外科治療.中國胸心血管外科臨床雜志, 2007, 14 (4):306-307.
11. 劉莉, 宋秀珍, 謝德軒.多普勒超聲心動圖對心臟原發性腫瘤的應用研究.中國醫學影像技術, 2008, 24 (6):896-899.
12. Bauner KU, Sourbron S, Picciolo M, et al. MR first pass perfusion of benign and malignant cardiac tumours-significant differences and diagnostic accuracy. Eur Radiol, 2012, 22 (1):73-82.
13. 李德強, 閻德民, 谷天祥, 等.右房粘液瘤的外科治療.中國醫科大學學報, 2001, 30 (2):156-157.
14. Qin C, Chen L, Xiao YB, et al. Giant primary leiomyoma of the right ventricle. J Card Surg, 2010, 25 (2):169-1671.
15. Karasu BB, Yeter E, Yilmazer D, et al. Primary valvular lipomatous hamartoma:a case report and a collective review of the literature. Cardiovasc Pathol, 2011, 20 (6):377-380.
16. Yuan SM, Shinfeld A, Raanani E. Tricuspid valve myxoma:a case report and a collective review of the literature. J Card Surg, 2009, 24 (1):69-72.
17. 高志, 路天怡, 許建屏, 等.心臟惡性腫痛10例分析.北京大學學報:醫學版, 2003, 35 (3):333-334.
18. 張勇, 梁家立.心臟原發惡性腫瘤五例報告.中華腫瘤防治雜志, 2012, 19 (22):1751-1752.
19. 張玉海, 谷天祥, 王春, 等.累及心臟的靜脈內平滑肌瘤的診斷策略和外科治療.中國醫科大學學報, 2012, 41 (12):1148-1149.
20. 李旻, 潘凌亞, 連麗娟.伴有心臟受累的靜脈內平滑肌瘤病臨床分析.現代婦產科進展, 2006, 15 (3):191-194.

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Diagnosis and Surgical Treatment of Malignant Cardiac Tumors

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