Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

TAN Wei ¹ , ZHENG Ping ^1,2 ,  GONG Renrong ^1,3

1. West China School of Nursing, Sichuan University/West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
2. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
3. Department of Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;

Corresponding?author：

GONG Renrong, Email: gongrenrong@wchscu.cn

Keywords：

Heart valve replacement; mid-to-long term; quality of life; influencing factor

DOI：

10.7507/1007-4848.202012016

Video：

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Objective To investigate the mid-to-long term quality of life (QOL) and influencing factors in the patients after heart valve replacement.Methods Convenient sampling method was used to recruit 224 patients who had heart valve replacement surgery in our hospital from June 2008 to June 2017. There were 63 males and 161 females, aged 18-83 (51.49±10.60) years. General information questionnaire and MOS SF-36 scale were used to collect data. Univariate analysis and multiple linear regression analysis were used to analyze and determine the influencing factors for the QOL.Results The total score of QOL of 224 patients was 71.78±17.60 points. All these scores of the patients were significantly lower than those of the general population of Chengdu (P<0.05) except the dimension of vitality. The QOL scores differences between sex, marital status, family income, working condition, the occurrence of anticoagulant complications and other complications were significant (P<0.05). Multivariate analysis showed that family income, working condition, the occurrence of anticoagulant complications and other complications could be included in the regression model, explaining 26.8% of total variance. Conclusion The mid-to-long term QOL is lower in the patients after heart valve replacement. Family income, working condition, anticoagulant complications and other complications are the main influencing factors for mid-to-long term QOL for patients after heart valve replacement.

Citation： TAN Wei, ZHENG Ping, GONG Renrong. Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(8): 1003-1007. doi: 10.7507/1007-4848.202012016 Copy

1.	中國心血管健康與疾病報告編寫組. 中國心血管健康與疾病報告2019概要. 心腦血管病防治, 2020, 20(5): 437-450.
2.	Ciuca C, Fortuna D, Ferrari S, et al. Cognitive and quality of life trajectory after either surgical or transcatheter aortic valve replacement in high-risk patients. G Ital Cardiol (Rome), 2016, 17(12 Suppl 1): 15S-21S.
3.	Tsang FH, Wong SJ, Cheung YF. Pulmonary valve replacement and quality-of-life assessment. Asian Cardiovasc Thorac Ann, 2016, 24(1): 5-11.
4.	Coelho P, Ferreira LN, Vital C, et al. Does aortic valve replacement surgery improve patients' quality of life? Acta Med Port, 2018, 31(7-8): 399-408.
5.	Jansen Klomp WW, Nierich AP, Peelen LM, et al. Survival and quality of life after surgical aortic valve replacement in octogenarians. J Cardiothorac Surg, 2016, 11: 38.
6.	Korteland NM, Top D, Borsboom GJ, et al. Quality of life and prosthetic aortic valve selection in non-elderly adult patients. Interact Cardiovasc Thorac Surg, 2016, 22(6): 723-728.
7.	Huygens SA, van der Kley F, Bekkers JA, et al. Beyond the clinical impact of aortic and pulmonary valve implantation: Health-related quality of life, informal care and productivity. Eur J Cardiothorac Surg, 2019, 55(4): 751-759.
8.	趙龍超, 楊展, 胡曉, 等. SF-12v2與SF-36v2在成都市居民人群中的等效性評價. 四川大學學報(醫學版), 2018, 49(1): 87-92.
9.	劉朝杰, 李寧秀, 任曉暉, 等. 36條目簡明量表在中國人群中的適用性研究. 華西醫科大學學報, 2001, 32(1): 39-42.
10.	Taillefer MC, Dupuis G, Hardy JF, et al. Quality of life before and after heart valve surgery is influenced by gender and type of valve. Qual Life Res, 2005, 14(3): 769-778.
11.	B?z L, Wiesel M, M?bius-Winkler S, et al. Depression and anxiety in elderly patients with severe symptomatic aortic stenosis persistently improves after transcatheter aortic valve replacement (TAVR). Int J Cardiol, 2020, 309: 48-54.
12.	吳麗仙, 丁巧玲, 李艷, 等. 心臟瓣膜置換術后患者生活質量與社會支持的相關性研究. 麗水學院學報, 2017, 39(2): 82-85.
13.	溫雅, 蔣曉蓮, 白陽靜, 等. 心臟瓣膜置換術后患者生存質量研究現狀. 華西醫學, 2016, 31(6): 1137-1141.
14.	Wang X, Xu B, Liang H, et al. Distribution characteristics and factors influencing oral warfarin adherence in patients after heart valve replacement. Patient Prefer Adherence, 2018, 12: 1641-1648.
15.	Pragt H, Pieper PG, van Slooten YJ, et al. Quality of life among patients with congenital heart disease after valve replacement. Semin Thorac Cardiovasc Surg, Autumn, 2019, 31(3): 549-558.
16.	于秋霞. 心臟瓣膜置換術后癥狀困擾與生活質量的關系. 護理實踐與研究, 2020, 17(17): 43-45.
17.	Arnold SV, Zhang Y, Baron SJ, et al. Impact of short-term complications on mortality and quality of life after transcatheter aortic valve replacement. JACC Cardiovasc Interv, 2019, 12(4): 362-369.
18.	Taghadosi M, Memarian R, Ahmadi F. The experiences of "difficult life" in heart valve replaced patients. Iran Red Crescent Med J, 2014, 16(8): e19147.
19.	Kottmaier M, Hettich I, Deutsch MA, et al. Quality of life and anxiety in younger patients after biological versus mechanical aortic valve replacement. Thorac Cardiovasc Surg, 2017, 65(3): 198-205.
20.	栗林, 王學寧, 郭萬鵬, 等. 微信平臺對心臟瓣膜置換術后出院患者口服華法林延續護理的效果. 中國藥物與臨床, 2017, 17(8): 1252-1254.
21.	盛衛勇, 晁陽陽, 趙國昌, 等. 二尖瓣置換術患者術后生存質量分析. 河南醫學研究, 2018, 27(23): 4260-4262.

1. 中國心血管健康與疾病報告編寫組. 中國心血管健康與疾病報告2019概要. 心腦血管病防治, 2020, 20(5): 437-450.
2. Ciuca C, Fortuna D, Ferrari S, et al. Cognitive and quality of life trajectory after either surgical or transcatheter aortic valve replacement in high-risk patients. G Ital Cardiol (Rome), 2016, 17(12 Suppl 1): 15S-21S.
3. Tsang FH, Wong SJ, Cheung YF. Pulmonary valve replacement and quality-of-life assessment. Asian Cardiovasc Thorac Ann, 2016, 24(1): 5-11.
4. Coelho P, Ferreira LN, Vital C, et al. Does aortic valve replacement surgery improve patients' quality of life? Acta Med Port, 2018, 31(7-8): 399-408.
5. Jansen Klomp WW, Nierich AP, Peelen LM, et al. Survival and quality of life after surgical aortic valve replacement in octogenarians. J Cardiothorac Surg, 2016, 11: 38.
6. Korteland NM, Top D, Borsboom GJ, et al. Quality of life and prosthetic aortic valve selection in non-elderly adult patients. Interact Cardiovasc Thorac Surg, 2016, 22(6): 723-728.
7. Huygens SA, van der Kley F, Bekkers JA, et al. Beyond the clinical impact of aortic and pulmonary valve implantation: Health-related quality of life, informal care and productivity. Eur J Cardiothorac Surg, 2019, 55(4): 751-759.
8. 趙龍超, 楊展, 胡曉, 等. SF-12v2與SF-36v2在成都市居民人群中的等效性評價. 四川大學學報(醫學版), 2018, 49(1): 87-92.
9. 劉朝杰, 李寧秀, 任曉暉, 等. 36條目簡明量表在中國人群中的適用性研究. 華西醫科大學學報, 2001, 32(1): 39-42.
10. Taillefer MC, Dupuis G, Hardy JF, et al. Quality of life before and after heart valve surgery is influenced by gender and type of valve. Qual Life Res, 2005, 14(3): 769-778.
11. B?z L, Wiesel M, M?bius-Winkler S, et al. Depression and anxiety in elderly patients with severe symptomatic aortic stenosis persistently improves after transcatheter aortic valve replacement (TAVR). Int J Cardiol, 2020, 309: 48-54.
12. 吳麗仙, 丁巧玲, 李艷, 等. 心臟瓣膜置換術后患者生活質量與社會支持的相關性研究. 麗水學院學報, 2017, 39(2): 82-85.
13. 溫雅, 蔣曉蓮, 白陽靜, 等. 心臟瓣膜置換術后患者生存質量研究現狀. 華西醫學, 2016, 31(6): 1137-1141.
14. Wang X, Xu B, Liang H, et al. Distribution characteristics and factors influencing oral warfarin adherence in patients after heart valve replacement. Patient Prefer Adherence, 2018, 12: 1641-1648.
15. Pragt H, Pieper PG, van Slooten YJ, et al. Quality of life among patients with congenital heart disease after valve replacement. Semin Thorac Cardiovasc Surg, Autumn, 2019, 31(3): 549-558.
16. 于秋霞. 心臟瓣膜置換術后癥狀困擾與生活質量的關系. 護理實踐與研究, 2020, 17(17): 43-45.
17. Arnold SV, Zhang Y, Baron SJ, et al. Impact of short-term complications on mortality and quality of life after transcatheter aortic valve replacement. JACC Cardiovasc Interv, 2019, 12(4): 362-369.
18. Taghadosi M, Memarian R, Ahmadi F. The experiences of "difficult life" in heart valve replaced patients. Iran Red Crescent Med J, 2014, 16(8): e19147.
19. Kottmaier M, Hettich I, Deutsch MA, et al. Quality of life and anxiety in younger patients after biological versus mechanical aortic valve replacement. Thorac Cardiovasc Surg, 2017, 65(3): 198-205.
20. 栗林, 王學寧, 郭萬鵬, 等. 微信平臺對心臟瓣膜置換術后出院患者口服華法林延續護理的效果. 中國藥物與臨床, 2017, 17(8): 1252-1254.
21. 盛衛勇, 晁陽陽, 趙國昌, 等. 二尖瓣置換術患者術后生存質量分析. 河南醫學研究, 2018, 27(23): 4260-4262.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement

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