Clinical efficacy analysis of different interventional approaches for patent ductus arteriosus in children (≤7 years)_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

ZHOU Zeming ¹ , WANG Hongmao ² ,  ZHENG Hong ¹ , SONG Huijun ¹ , LI Shiguo ¹ , YAN Chaowu ¹ , HU Haibo ¹ , LIU Qiong ¹ , XU Zhongying ¹ , XU Liang ¹ , LV Jianhua ¹ , ZHANG Gejun ¹ , WAN Junyi ¹ , JIN Jinglin ¹

1. Department of Structural Heart Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China;
2. Department of Cardiovascular Diseases, Children’s Hospital Affiliated to Capital Institute of Pediatrics, Beijing, 100020, P. R. China;

Corresponding?author：

ZHENG Hong, Email: zheng_hung@126.com

Keywords：

Patent ductus arteriosus; interventional closure; conventional arteriovenous approach; simple venous approach; retrograde femoral artery approach

DOI：

10.7507/1007-4848.202104002

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the safety and effectiveness of different interventional approaches for the treatment of patent ductus arteriosus (PDA) in children.Methods The children (≤7 years) who underwent interventional treatment for PDA from 2019 to 2020 in our hospital were retrospectively included. The patients were divided into 3 groups according to the procedures: a conventional arteriovenous approach group, a simple venous approach group, and a retrograde femoral artery approach group. The clinical efficacy of the patients was compared. Results A total of 220 patients were included. There were 78 males and 142 females, with an average age of 3.21±1.73 years, weight of 14.99±5.35 kg, and height of 96.19±15.77 cm. The average diameter of the PDA was 3.35±1.34 mm. A total of 85 patients received a conventional arteriovenous approach, 104 patients received a simple venous approach, and 31 patients received a retrograde femoral artery approach. The diameter of PDA in the retrograde femoral artery group was smaller than that in the other two groups (3.44±1.43 mm vs. 1.99±0.55 mm; 3.69±1.17 mm vs. 1.99±0.55 mm, P<0.001); the contrast medium usage [40 (30, 50) mL vs. 20 (20, 30) mL; 35 (25, 50) mL vs. 20 (20, 30) mL, P≤0.001] and operation time [32 (26, 44) min vs. 25 (23, 30) min; 29 (25, 38) min vs. 25 (23, 30) min, P<0.05] in the simple venous approach group were significantly less or shorter than those in the other two groups; the length of hospital stay of the conventional arteriovenous group was longer than that in the other two groups [3 (3, 5) d vs. 4 (3, 6) d; 4 (3, 5) d vs. 4 (3, 6) d, P<0.05]. There was no significant difference in postoperative complications.Conclusion It is safe and effective to close PDA through simple venous approach. The retrograde femoral artery approach has the advantage of simplifying the surgical procedure for PDA with small diameters.

Citation： ZHOU Zeming, WANG Hongmao, ZHENG Hong, SONG Huijun, LI Shiguo, YAN Chaowu, HU Haibo, LIU Qiong, XU Zhongying, XU Liang, LV Jianhua, ZHANG Gejun, WAN Junyi, JIN Jinglin. Clinical efficacy analysis of different interventional approaches for patent ductus arteriosus in children (≤7 years). Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2023, 30(5): 699-703. doi: 10.7507/1007-4848.202104002 Copy

1.	Schneider DJ, Moore JW. Patent ductus arteriosus. Circulation, 2006, 114(17): 1873-1882.
2.	Porstmann W, Wierny L, Warnke H. Closure of persistent ductus arteriosus without thoracotomy. Ger Med Mon, 1967, 12(6): 259-261.
3.	Choi DY, Kim NY, Jung MJ, et al. The results of transcatheter occlusion of patent ductus arteriosus: Success rate and complications over 12 years in a single center. Korean Circ J, 2010, 40(5): 230-234.
4.	Djer MM, Saputro DD, Putra ST, et al. Transcatheter closure of patent ductus arteriosus: 11 years of clinical experience in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Pediatr Cardiol, 2015, 36(5): 1070-1074.
5.	Jin M, Liang YM, Wang XF, et al. A retrospective study of 1, 526 cases of transcatheter occlusion of patent ductus arteriosus. Chin Med J (Engl), 2015, 128(17): 2284-2289.
6.	Baruteau AE, Hasco?t S, Baruteau J, et al. Transcatheter closure of patent ductus arteriosus: Past, present and future. Arch Cardiovasc Dis, 2014, 107(2): 122-132.
7.	Liu J, Gao L, Tan HL, et al. Transcatheter closure through single venous approach for young children with patent ductus arteriosus: A retrospective study of 686 cases. Medicine (Baltimore), 2018, 97(35): e11958.
8.	王炎. 超聲心動圖估測動脈導管未閉內徑可靠性的評估. 四川大學, 2007.
9.	周冀瑋, 易豈建, 王獻民. 兒童動脈導管未閉介入治療單中心療效及中長期隨訪觀察. 臨床兒科雜志, 2020, 38(4): 275-280.
10.	孟祥春, 蔡華波, 李志川, 等. 動脈導管造影聯合經胸超聲在動脈導管未閉封堵術治療中的應用. 中國當代兒科雜志, 2010, 12(2): 103-105.
11.	王震, 高磊, 解啟蓮, 等. 經導管單純靜脈途徑封堵動脈導管未閉. 臨床薈萃, 2007, 22(14): 1025-1026.
12.	張偉華, 田民, 雷蕓, 等. 兩種單靜脈法與傳統 Amplatzer 法治療動脈導管未閉. 中國介入影像與治療學, 2007, 4(2): 101-105.
13.	羅國新, 何建新, 龔志華. 單純股靜脈入路封堵治療兒童動脈導管未閉. 廣東醫學, 2014, (16): 2579-2580.
14.	Wilson WM, Shah A, Osten MD, et al. Clinical outcomes after percutaneous patent ductus arteriosus closure in adults. Can J Cardiol, 2020, 36(6): 837-843.
15.	Gruenstein DH, Ebeid M, Radtke W, et al. Transcatheter closure of patent ductus arteriosus using the AMPLATZER? duct occluder Ⅱ (ADO Ⅱ). Catheter Cardiovasc Interv, 2017, 89(6): 1118-1128.
16.	Morgan G, Tometzki AJ, Martin RP. Transcatheter closure of long tubular patent arterial ducts: The AMPLATZER duct occluder Ⅱ-A new and valuable tool. Catheter Cardiovasc Interv, 2009, 73(4): 576-580.
17.	張戈軍, 徐仲英, 蔣世良, 等. 第二代 Amplatzer 動脈導管未閉封堵器經股動脈逆行插管行室間隔缺損封堵術療效評價. 臨床薈萃, 2015, 30(6): 601-604.

1. Schneider DJ, Moore JW. Patent ductus arteriosus. Circulation, 2006, 114(17): 1873-1882.
2. Porstmann W, Wierny L, Warnke H. Closure of persistent ductus arteriosus without thoracotomy. Ger Med Mon, 1967, 12(6): 259-261.
3. Choi DY, Kim NY, Jung MJ, et al. The results of transcatheter occlusion of patent ductus arteriosus: Success rate and complications over 12 years in a single center. Korean Circ J, 2010, 40(5): 230-234.
4. Djer MM, Saputro DD, Putra ST, et al. Transcatheter closure of patent ductus arteriosus: 11 years of clinical experience in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Pediatr Cardiol, 2015, 36(5): 1070-1074.
5. Jin M, Liang YM, Wang XF, et al. A retrospective study of 1, 526 cases of transcatheter occlusion of patent ductus arteriosus. Chin Med J (Engl), 2015, 128(17): 2284-2289.
6. Baruteau AE, Hasco?t S, Baruteau J, et al. Transcatheter closure of patent ductus arteriosus: Past, present and future. Arch Cardiovasc Dis, 2014, 107(2): 122-132.
7. Liu J, Gao L, Tan HL, et al. Transcatheter closure through single venous approach for young children with patent ductus arteriosus: A retrospective study of 686 cases. Medicine (Baltimore), 2018, 97(35): e11958.
8. 王炎. 超聲心動圖估測動脈導管未閉內徑可靠性的評估. 四川大學, 2007.
9. 周冀瑋, 易豈建, 王獻民. 兒童動脈導管未閉介入治療單中心療效及中長期隨訪觀察. 臨床兒科雜志, 2020, 38(4): 275-280.
10. 孟祥春, 蔡華波, 李志川, 等. 動脈導管造影聯合經胸超聲在動脈導管未閉封堵術治療中的應用. 中國當代兒科雜志, 2010, 12(2): 103-105.
11. 王震, 高磊, 解啟蓮, 等. 經導管單純靜脈途徑封堵動脈導管未閉. 臨床薈萃, 2007, 22(14): 1025-1026.
12. 張偉華, 田民, 雷蕓, 等. 兩種單靜脈法與傳統 Amplatzer 法治療動脈導管未閉. 中國介入影像與治療學, 2007, 4(2): 101-105.
13. 羅國新, 何建新, 龔志華. 單純股靜脈入路封堵治療兒童動脈導管未閉. 廣東醫學, 2014, (16): 2579-2580.
14. Wilson WM, Shah A, Osten MD, et al. Clinical outcomes after percutaneous patent ductus arteriosus closure in adults. Can J Cardiol, 2020, 36(6): 837-843.
15. Gruenstein DH, Ebeid M, Radtke W, et al. Transcatheter closure of patent ductus arteriosus using the AMPLATZER? duct occluder Ⅱ (ADO Ⅱ). Catheter Cardiovasc Interv, 2017, 89(6): 1118-1128.
16. Morgan G, Tometzki AJ, Martin RP. Transcatheter closure of long tubular patent arterial ducts: The AMPLATZER duct occluder Ⅱ-A new and valuable tool. Catheter Cardiovasc Interv, 2009, 73(4): 576-580.
17. 張戈軍, 徐仲英, 蔣世良, 等. 第二代 Amplatzer 動脈導管未閉封堵器經股動脈逆行插管行室間隔缺損封堵術療效評價. 臨床薈萃, 2015, 30(6): 601-604.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Clinical efficacy analysis of different interventional approaches for patent ductus arteriosus in children (≤7 years)

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content