Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 ZHANG Weidong , JIN Feng , LU Weixin

Department of General Surgery, No.8 People’s Hospital of Tongzhou District, Nantong, Jiangsu 226361, P.R.China;

Corresponding?author：

ZHANG Weidong, Email: zzhj321@163.com

Keywords：

gallbladder disease; suturesuspension single hole laparoscopic cholecystectomy; laparoscopic cholecystectomy; curative effect; safety

DOI：

10.7507/1007-9424.201608017

Video：

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Objective To compare the clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy (LC) in the treatment of gallbladder disease. Methods A total of 86 cases who got treatment in our hospital from February 2014 to July 2015 were collected prospectively, and then 86 cases were divided into 2 groups: 43 cases of control group underwent LC and 43 cases of experimental group underwent suturesuspension single hole laparoscopic cholecystectomy. Clinical efficacy and safety of the two groups were compared. Results ① Complication. No one suffered from bile duct injury, bile leakage, bile duct stricture, and umbilical hernia; but there were 2 cases suffered from complications in control group, including 1 case of abdominal pain and 1 case of bloating, and the morbidity was 4.65% (2/43). The morbidity of experimental group was 0, there was no significant difference between the 2 groups in the morbidity (P>0.05). During the follow-up period, 1 case suffered from long-term compilation in experimental group, and 2 cases in normal group, there was no significant difference in the long-term complication between the 2 groups (P>0.05). ② Operation and hospitalization. The blood loss and operation time in the experimental group were lower than those of the control group (P<0.05), but there was no significant difference in the hospital stay and hospitalization cost between the 2 groups (P>0.05). ③ Postoperative electrolytes, liver and kidney function. The levels of Na⁺ and K⁺ in the experimental group were higher than those of the control group (P<0.05), and the levels of alanine aminotransferase and aspartate aminotransferase were lower than those of control group (P<0.01), but there was no significant difference in the blood urea nitrogen and serum creatinine between the 2 groups (P>0.05). ④ The recovery of gastrointestinal function after surgery. The anal exhaust time and bowel sounds recovery time in experimental group were shorter than those of the control group (P<0.01). Conclusion Suturesus-pension single hole laparoscopic cholecystectomy in the treatment of gallbladder disease is safe, effective, and minimally invasive, and it has little disturbance on gastrointestinal function and liver function, which is worthy of clinical application.

Citation： ZHANG Weidong, JIN Feng, LU Weixin. Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2017, 24(3): 312-316. doi: 10.7507/1007-9424.201608017 Copy

1.	?胡海, 朱江帆, 所廣軍, 等. 新型經臍入路腹腔鏡膽囊切除術. 腹腔鏡外科雜志, 2008, 13(2): 145-147.
2.	劉勇, 楊帆, 王雁飛, 等. 25 例經臍單孔腹腔鏡膽囊切除術的臨床應用體會. 重慶醫學, 2014, 43(16): 2056-2058.
3.	Tacchino R, Greco F, Matera D. Single-incision laparoscopic cholecystectomy: surgery without a visible scar. Surg Endosc, 2009, 23(4): 896-899.
4.	秦鳴放, 趙宏志. 肝內外膽管結石的微創治療. 腹腔鏡外科雜志, 2012, 17(3): 166-168.
5.	Rao PP, Bhagwat SM, Rane A,et al. The feasibility of single port laparoscopic cholecystectomy: a pilot study of 20 cases. HPB (Oxford), 2008, 10(5): 336-340.
6.	劉南, 張光永, 胡三元. 懸吊式經臍單孔腹腔鏡膽囊切除術與傳統腹腔鏡膽囊切除術的對比研究. 腹腔鏡外科雜志, 2011, 16(2): 96-99.
7.	張忠濤, 韓威, 李建設, 等. 經臍單孔腹腔鏡膽囊切除術 1 例報告. 腹腔鏡外科雜志, 2008, 13(4): 314.
8.	馮琦. 經臍單孔腹腔鏡膽囊切除術治療急性膽囊炎療效觀察. 中國現代藥物應用, 2016, 10(10): 66-67.
9.	王永坤, 朱江帆. 虛擬內鏡技術在消化系統疾病診斷中的應用. 中國微創外科雜志, 2010, 10(3): 278-280.
10.	李祺. 針刺穿線膽囊懸吊在經臍單孔腹腔鏡膽囊切除術中的臨床對照研究. 中國醫療前沿, 2012, 7(19): 3-4, 54.
11.	胡昆鵬, 姚志成, 黃品助, 等. 單孔腹腔鏡膽囊切除術 (附視頻). 中華肝臟外科手術學電子雜志, 2014, 3(4): 55-56.
12.	蔣澤生, 程遠, 徐小平, 等. 吊線法與三器械法單孔腹腔鏡膽囊切除術比較. 中華醫學雜志, 2013, 93(6): 455-458.
13.	李述劍. 經臍單孔腹腔鏡膽囊切除術的安全性及可行性. 中外醫學研究, 2016, 14(23): 126-128.
14.	徐獻忠, 丁建忠, 孫勝利, 等. 單孔腹腔鏡 (完全經臍) 下膽囊切除術 25 例臨床報告. 中外醫學研究, 2016, 14(10): 93-94.
15.	張祺, 賀長林. 單孔法腹腔鏡技術在膽囊切除術中的臨床研究. 中國現代醫生, 2016, 54(21): 39-41.
16.	王強, 賈新能, 王志敏, 等. 經臍單孔與傳統三孔腹腔鏡膽囊切除術的臨床療效比較. 浙江醫學, 2016, 38(1): 22-25.
17.	馬君, 王元宇, 牟一平. 經臍單孔腹腔鏡與普通腹腔鏡膽囊切除術后臍部感染的分析. 浙江臨床醫學, 2016, 18(10): 1841-1842.
18.	鄭凱欣, 許銳銳, 韓慧, 等. 單孔與多孔腹腔鏡膽囊切除術的安全性 Meta 分析. 中華腔鏡外科雜志(電子版), 2016, 9(3): 146-151.
19.	李欣, 侯純升, 白洋, 等. 單孔腹腔鏡膽囊切除術的學習曲線: 累積求和分析法. 中國微創外科雜志, 2016, 16(3): 241-244.
20.	張雁凱, 宮軻, 張成才, 等. 腹腔鏡膽囊切除術后患者血液高凝狀態的危險因素分析. 中國醫藥, 2016, 11(2): 250-254.
21.	顧炯, 孫愛學, 魏曉明, 等. 腹腔鏡脾切除術在乙肝后肝硬化門靜脈高壓癥脾腫大患者中的應用. 中華肝臟外科手術學電子雜志, 2016, 5(5): 308-310.
22.	張憲光, 程遠, 蔣澤生, 等. 單孔腹腔鏡技術治療急性膽囊炎 30 例. 中華肝膽外科雜志, 2016, 22(3): 202-203.
23.	Navarra G, La Malfa G, Bartolotta G,et al. The invisible cholecystectomy: a different way. Surg Endosc, 2008, 22(9): 2103.
24.	郭見光, 黃玉芹, 李欣, 等. 經臍單孔腹腔鏡手術治療急性膽囊炎的療效分析. 中國衛生標準管理, 2016, 7(12): 80-82.
25.	賈鵬松. 經臍單孔腹腔鏡膽囊切除術的效果及對患者血管內皮功能和炎癥因子的影響. 中國衛生標準管理, 2016, 7(12): 45-46.

1. ?胡海, 朱江帆, 所廣軍, 等. 新型經臍入路腹腔鏡膽囊切除術. 腹腔鏡外科雜志, 2008, 13(2): 145-147.
2. 劉勇, 楊帆, 王雁飛, 等. 25 例經臍單孔腹腔鏡膽囊切除術的臨床應用體會. 重慶醫學, 2014, 43(16): 2056-2058.
3. Tacchino R, Greco F, Matera D. Single-incision laparoscopic cholecystectomy: surgery without a visible scar. Surg Endosc, 2009, 23(4): 896-899.
4. 秦鳴放, 趙宏志. 肝內外膽管結石的微創治療. 腹腔鏡外科雜志, 2012, 17(3): 166-168.
5. Rao PP, Bhagwat SM, Rane A,et al. The feasibility of single port laparoscopic cholecystectomy: a pilot study of 20 cases. HPB (Oxford), 2008, 10(5): 336-340.
6. 劉南, 張光永, 胡三元. 懸吊式經臍單孔腹腔鏡膽囊切除術與傳統腹腔鏡膽囊切除術的對比研究. 腹腔鏡外科雜志, 2011, 16(2): 96-99.
7. 張忠濤, 韓威, 李建設, 等. 經臍單孔腹腔鏡膽囊切除術 1 例報告. 腹腔鏡外科雜志, 2008, 13(4): 314.
8. 馮琦. 經臍單孔腹腔鏡膽囊切除術治療急性膽囊炎療效觀察. 中國現代藥物應用, 2016, 10(10): 66-67.
9. 王永坤, 朱江帆. 虛擬內鏡技術在消化系統疾病診斷中的應用. 中國微創外科雜志, 2010, 10(3): 278-280.
10. 李祺. 針刺穿線膽囊懸吊在經臍單孔腹腔鏡膽囊切除術中的臨床對照研究. 中國醫療前沿, 2012, 7(19): 3-4, 54.
11. 胡昆鵬, 姚志成, 黃品助, 等. 單孔腹腔鏡膽囊切除術 (附視頻). 中華肝臟外科手術學電子雜志, 2014, 3(4): 55-56.
12. 蔣澤生, 程遠, 徐小平, 等. 吊線法與三器械法單孔腹腔鏡膽囊切除術比較. 中華醫學雜志, 2013, 93(6): 455-458.
13. 李述劍. 經臍單孔腹腔鏡膽囊切除術的安全性及可行性. 中外醫學研究, 2016, 14(23): 126-128.
14. 徐獻忠, 丁建忠, 孫勝利, 等. 單孔腹腔鏡 (完全經臍) 下膽囊切除術 25 例臨床報告. 中外醫學研究, 2016, 14(10): 93-94.
15. 張祺, 賀長林. 單孔法腹腔鏡技術在膽囊切除術中的臨床研究. 中國現代醫生, 2016, 54(21): 39-41.
16. 王強, 賈新能, 王志敏, 等. 經臍單孔與傳統三孔腹腔鏡膽囊切除術的臨床療效比較. 浙江醫學, 2016, 38(1): 22-25.
17. 馬君, 王元宇, 牟一平. 經臍單孔腹腔鏡與普通腹腔鏡膽囊切除術后臍部感染的分析. 浙江臨床醫學, 2016, 18(10): 1841-1842.
18. 鄭凱欣, 許銳銳, 韓慧, 等. 單孔與多孔腹腔鏡膽囊切除術的安全性 Meta 分析. 中華腔鏡外科雜志(電子版), 2016, 9(3): 146-151.
19. 李欣, 侯純升, 白洋, 等. 單孔腹腔鏡膽囊切除術的學習曲線: 累積求和分析法. 中國微創外科雜志, 2016, 16(3): 241-244.
20. 張雁凱, 宮軻, 張成才, 等. 腹腔鏡膽囊切除術后患者血液高凝狀態的危險因素分析. 中國醫藥, 2016, 11(2): 250-254.
21. 顧炯, 孫愛學, 魏曉明, 等. 腹腔鏡脾切除術在乙肝后肝硬化門靜脈高壓癥脾腫大患者中的應用. 中華肝臟外科手術學電子雜志, 2016, 5(5): 308-310.
22. 張憲光, 程遠, 蔣澤生, 等. 單孔腹腔鏡技術治療急性膽囊炎 30 例. 中華肝膽外科雜志, 2016, 22(3): 202-203.
23. Navarra G, La Malfa G, Bartolotta G,et al. The invisible cholecystectomy: a different way. Surg Endosc, 2008, 22(9): 2103.
24. 郭見光, 黃玉芹, 李欣, 等. 經臍單孔腹腔鏡手術治療急性膽囊炎的療效分析. 中國衛生標準管理, 2016, 7(12): 80-82.
25. 賈鵬松. 經臍單孔腹腔鏡膽囊切除術的效果及對患者血管內皮功能和炎癥因子的影響. 中國衛生標準管理, 2016, 7(12): 45-46.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis of clinical efficacy and safety of suturesuspension single hole laparoscopic cholecystectomy and traditional laparoscopic cholecystectomy in the treatment of gallbladder disease

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