Controversy of preoperative biliary drainage for resectable hilar cholangiocarcinoma_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

YE Zhengchen , Chen Xiaoxing ,  WANG Lin

Hepatopancreatobiliary Surgery Dept.2, Second Affiliated Hospital of Kunming Medical University, Kunming 650106, R. P. China;

Corresponding?author：

WANG Lin, Email: linwang2019@126.com

Keywords：

hilar cholangiocarcinoma; Klatskin tumor, preoperative biliary drainage; ?

DOI：

10.7507/1007-9424.201909122

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the advantages and disadvantages of preoperative biliary drainage, the timing of preoperative biliary drainage, and the characteristics of various drainage methods for resectable hilar cholangiocarcinoma.Methods By reviewing relevant literatures at home and abroad in the past 20 years, the controversies related to the preoperative biliary drainage, surgical biliary drainage, and various drainage methods for resectable hilar cholangiocarcinoma were reviewed.Results There is still a great deal of controversy about whether preoperative bile duct drainage is required for resectable hilar cholangiocarcinoma routinely, but there is a consensus on the timing of preoperative biliary drainage, and various drainage methods have their own characteristics.Conclusions The main treatment for hilar cholangiocarcinoma is radical surgical resection, but cholestasis is often caused by malignant biliary obstruction, which makes it difficult to manage perioperatively. A large number of prospective studies are needed to provide more evidence for the need for routine preoperative biliary drainage in patients with hilar cholangiocarcinoma who can undergo resection.

Citation： YE Zhengchen, Chen Xiaoxing, WANG Lin. Controversy of preoperative biliary drainage for resectable hilar cholangiocarcinoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2020, 27(6): 763-767. doi: 10.7507/1007-9424.201909122 Copy

1.	蕭嘉銘, 董高宏. 肝門部膽管癌的外科治療現狀. 中國腫瘤外科雜志, 2015, 7(6): 390-393.
2.	劉辰, 姜小清. 肝門部膽管癌根治性切除的可能性評估. 中國普外基礎與臨床雜志, 2016, 23(11): 1299-1303.
3.	黃志強. 肝門部膽管癌外科治療的現狀與我見. 中國實用外科雜志, 2007, 27(5): 341-346.
4.	Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of Vater. Ann Surg, 1935, 102(4): 763-79.
5.	McPherson GA, Benjamin IS, Hodgson HJ, et al. Pre-operative percutaneous transhepatic biliary drainage: the results of a controlled trial. Br J Surg, 1984, 71(5): 371-375.
6.	Pavlidis ET, Pavlidis TE. Pathophysiological consequences of obstructive jaundice and perioperative management. Hepatobiliary Pancreat Dis Int, 2018, 17(1): 17-21.
7.	鞏鵬, 王忠裕, 王洪江, 等. SOD 基因轉染大鼠肝細胞對膽汁毒性損害的保護. 中國實用外科雜志, 2003, 23(6): 346-347.
8.	董家鴻, 鄭樹森, 陳孝平, 等. 肝切除術前肝臟儲備功能評估的專家共識(2011 版). 中華消化外科雜志, 2011, 10(1): 20-25.
9.	郭晗, 陳朋, 袁鵬, 等. 術前膽道引流對肝門膽管癌術后病人的影響的 Meta 分析. 肝膽外科雜志, 2017, 25(3): 185-189.
10.	Wang Y, Fu W, Tang Z, et al. Effect of preoperative cholangitis on prognosis of patients with hilar cholangiocarcinoma: A systematic review and meta-analysis. Medicine, 2018, 97(34): e12025.
11.	Ribero D, Zimmitti G, Aloia TA, et al. Preoperative cholangitis and future liver remnant volume determine the risk of liver failure in patients undergoing resection for hilar cholangiocarcinoma. J Am Coll Surg, 2016, 223(1): 87-97.
12.	Cassani LS, Chouhan J, Chan C, et al. Biliary decompression in perihilar cholangiocarcinoma improves survival: a single-center retrospective analysis. Dig Dis Sci, 2019, 64(2): 561-569.
13.	Wang L, Yu WF. Obstructive jaundice and perioperative management. Acta Anaesthesiol Taiwan, 2014, 52(1): 22-29.
14.	國際肝膽胰學會中國分會, 中華醫學會外科學分會肝臟外科學組. 膽管癌診斷與治療-外科專家共識. 臨床肝膽病雜志, 2015, 31(1): 12-16.
15.	Nimura Y. Preoperative biliary drainage before resection for cholangiocarcinoma (Pro). HPB (Oxford), 2008, 10(2): 130-133.
16.	Makino H, Shimizu H, Ito H, et al. Changes in growth factor and cytokine expression in biliary obstructed rat liver and their relationship with delayed liver regeneration after partial hepatectomy. World J Gastroenterol, 2006, 12(13): 2053-2059.
17.	Ramanathan R, Borrebach J, Tohme S, et al. Preoperative biliary drainage is associated with increased complications after liver resection for proximal cholangiocarcinoma. J Gastrointest Surg, 2018, 22(11): 1950-1957.
18.	Wahab MA, El Hanafy E, El Nakeeb A, et al. Postoperative outcome after major liver resection in jaundiced patients with proximal bile duct cancer without preoperative biliary drainage. Dig Surg, 2015, 32(6): 426-432.
19.	Xiong JJ, Nunes QM, Huang W, et al. Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy. World J Gastroenterol, 2013, 19(46): 8731-8739.
20.	Cai Y, Tang Q, Xiong, X, et al. Preoperative biliary drainage versus direct surgery for perihilar cholangiocarcinoma: A retrospective study at a single center. Biosci Trends, 2017, 11(3): 319-325.
21.	Sewnath ME, Karsten TM, Prins MH, et al. A meta-analysis on the efficacy of preoperative biliary drainage for tumors causing obstructive jaundice. Ann Surg, 2002, 236(1): 17-27.
22.	金昌國, 楊滔, 董家鴻. 肝門部膽管癌大范圍肝切除術前膽道引流作用的臨床研究. 軍事醫學, 2013, 37(7): 529-534.
23.	Mansour JC, Aloia TA, Crane CH, et al. Hilar cholangiocarcinoma: expert consensus statement. HPB (Oxford), 2015, 17(8): 691-699.
24.	鄭樹國, 鄭樹國, 項燦宏, 等. 肝門部膽管癌診斷和治療指南(2013 版). 中華外科雜志, 2013, 51(10): 865-871.
25.	中國抗癌協會. 肝門部膽管癌規范化診治專家共識(2015). 中華肝膽外科雜志, 2015, 21(8): 505-511.
26.	Zhang XF, Beal EW, Merath K, et al. Oncologic effects of preoperative biliary drainage in resectable hilar cholangio-carcinoma: percutaneous biliary drainage has no adverse effects on survival. J Surg Oncol, 2018, 117(6): 1267-1277.
27.	Hirano S, Tanaka E, Tsuchikawa T, et al. Oncological benefit of preoperative endoscopic biliary drainage in patients with hilar cholangiocarcinoma. J Hepatobiliary Pancreat Sci, 2014, 21(8): 533-540.
28.	Al Mahjoub A, Menahem B, Fohlen A, et al. Preoperative biliary drainage in patients with resectable perihilar cholangiocarcinoma: is percutaneous transhepatic biliary drainage safer and more effective than endoscopic biliary drainage? A meta-analysis. J Vasc Interv Radiol, 2017, 28(4): 576-582.
29.	Tang Z, Yang Y, Meng W, et al. Best option for preoperative biliary drainage in Klatskin tumor: A systematic review and meta-analysis. Medicine (Baltimore), 2017, 96(43): e8372.
30.	Liu JG, Wu J, Wang J, et al. Endoscopic biliary drainage versus percutaneous transhepatic biliary drainage in patients with resectable hilar cholangiocarcinoma: a systematic review and meta-analysis. J Laparoendosc Adv Surg Tech, 2018, 28(9): 1053-1060.
31.	Hameed A, Pang T, Chiou J, et al. Percutaneous vs. endoscopic pre-operative biliary drainage in hilar cholangiocarcinoma-a systematic review and meta-analysis. HPB (Oxford), 2016, 18(5): 400-410.
32.	Wang C, Xu Y, Lu X. Should preoperative biliary drainage be routinely performed for obstructive jaundice with resectable tumor? Hepatobiliary Surg Nutr, 2013, 2(5): 266-271.
33.	Jo JH, Chung MJ, Han DH, et al. Best options for preoperative biliary drainage in patients with Klatskin tumors. Surg Endosc, 2017, 31(1): 422-429.
34.	Kawakami H, Kuwatani M, Onodera M, et al. Endoscopic nasobiliary drainage is the most suitable preoperative biliary drainage method in the management of patients with hilar cholangiocarcinoma. J Gastroenterol, 2011, 46(2): 242-248.
35.	Higuchi R, Yazawa T, Uemura S, et al. ENBD is associated with decreased tumor dissemination compared to PTBD in perihilar cholangiocarcinoma. J Gastrointest Surg, 2017, 21(9): 1506-1514.
36.	張輝, 張振, 張海濤, 等. 肝門部膽管癌根治術前經內鏡鼻膽管引流和經皮經肝膽管造影引流術的臨床效果觀察. 腹部外科, 2017, 30(3): 197-201.
37.	Kang MJ, Choi YS, Jang JY, et al. Catheter tract recurrence after percutaneous biliary drainage for hilar cholangiocarcinoma. World J Surg, 2013, 37(2): 437-442.
38.	Paik WH, Loganathan N, Hwang JH. Preoperative biliary drainage in hilar cholangiocarcinoma: when and how? World J Gastrointest Endosc, 2014, 6(3): 68-73.
39.	Komaya K, Ebata T, Yokoyama Y, et al. Verification of the oncologic inferiority of percutaneous biliary drainage to endoscopic drainage: a propensity score matching analysis of resectable perihilar cholangiocarcinoma. Surgery, 2017, 161(2): 394-404.

1. 蕭嘉銘, 董高宏. 肝門部膽管癌的外科治療現狀. 中國腫瘤外科雜志, 2015, 7(6): 390-393.
2. 劉辰, 姜小清. 肝門部膽管癌根治性切除的可能性評估. 中國普外基礎與臨床雜志, 2016, 23(11): 1299-1303.
3. 黃志強. 肝門部膽管癌外科治療的現狀與我見. 中國實用外科雜志, 2007, 27(5): 341-346.
4. Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of Vater. Ann Surg, 1935, 102(4): 763-79.
5. McPherson GA, Benjamin IS, Hodgson HJ, et al. Pre-operative percutaneous transhepatic biliary drainage: the results of a controlled trial. Br J Surg, 1984, 71(5): 371-375.
6. Pavlidis ET, Pavlidis TE. Pathophysiological consequences of obstructive jaundice and perioperative management. Hepatobiliary Pancreat Dis Int, 2018, 17(1): 17-21.
7. 鞏鵬, 王忠裕, 王洪江, 等. SOD 基因轉染大鼠肝細胞對膽汁毒性損害的保護. 中國實用外科雜志, 2003, 23(6): 346-347.
8. 董家鴻, 鄭樹森, 陳孝平, 等. 肝切除術前肝臟儲備功能評估的專家共識(2011 版). 中華消化外科雜志, 2011, 10(1): 20-25.
9. 郭晗, 陳朋, 袁鵬, 等. 術前膽道引流對肝門膽管癌術后病人的影響的 Meta 分析. 肝膽外科雜志, 2017, 25(3): 185-189.
10. Wang Y, Fu W, Tang Z, et al. Effect of preoperative cholangitis on prognosis of patients with hilar cholangiocarcinoma: A systematic review and meta-analysis. Medicine, 2018, 97(34): e12025.
11. Ribero D, Zimmitti G, Aloia TA, et al. Preoperative cholangitis and future liver remnant volume determine the risk of liver failure in patients undergoing resection for hilar cholangiocarcinoma. J Am Coll Surg, 2016, 223(1): 87-97.
12. Cassani LS, Chouhan J, Chan C, et al. Biliary decompression in perihilar cholangiocarcinoma improves survival: a single-center retrospective analysis. Dig Dis Sci, 2019, 64(2): 561-569.
13. Wang L, Yu WF. Obstructive jaundice and perioperative management. Acta Anaesthesiol Taiwan, 2014, 52(1): 22-29.
14. 國際肝膽胰學會中國分會, 中華醫學會外科學分會肝臟外科學組. 膽管癌診斷與治療-外科專家共識. 臨床肝膽病雜志, 2015, 31(1): 12-16.
15. Nimura Y. Preoperative biliary drainage before resection for cholangiocarcinoma (Pro). HPB (Oxford), 2008, 10(2): 130-133.
16. Makino H, Shimizu H, Ito H, et al. Changes in growth factor and cytokine expression in biliary obstructed rat liver and their relationship with delayed liver regeneration after partial hepatectomy. World J Gastroenterol, 2006, 12(13): 2053-2059.
17. Ramanathan R, Borrebach J, Tohme S, et al. Preoperative biliary drainage is associated with increased complications after liver resection for proximal cholangiocarcinoma. J Gastrointest Surg, 2018, 22(11): 1950-1957.
18. Wahab MA, El Hanafy E, El Nakeeb A, et al. Postoperative outcome after major liver resection in jaundiced patients with proximal bile duct cancer without preoperative biliary drainage. Dig Surg, 2015, 32(6): 426-432.
19. Xiong JJ, Nunes QM, Huang W, et al. Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy. World J Gastroenterol, 2013, 19(46): 8731-8739.
20. Cai Y, Tang Q, Xiong, X, et al. Preoperative biliary drainage versus direct surgery for perihilar cholangiocarcinoma: A retrospective study at a single center. Biosci Trends, 2017, 11(3): 319-325.
21. Sewnath ME, Karsten TM, Prins MH, et al. A meta-analysis on the efficacy of preoperative biliary drainage for tumors causing obstructive jaundice. Ann Surg, 2002, 236(1): 17-27.
22. 金昌國, 楊滔, 董家鴻. 肝門部膽管癌大范圍肝切除術前膽道引流作用的臨床研究. 軍事醫學, 2013, 37(7): 529-534.
23. Mansour JC, Aloia TA, Crane CH, et al. Hilar cholangiocarcinoma: expert consensus statement. HPB (Oxford), 2015, 17(8): 691-699.
24. 鄭樹國, 鄭樹國, 項燦宏, 等. 肝門部膽管癌診斷和治療指南(2013 版). 中華外科雜志, 2013, 51(10): 865-871.
25. 中國抗癌協會. 肝門部膽管癌規范化診治專家共識(2015). 中華肝膽外科雜志, 2015, 21(8): 505-511.
26. Zhang XF, Beal EW, Merath K, et al. Oncologic effects of preoperative biliary drainage in resectable hilar cholangio-carcinoma: percutaneous biliary drainage has no adverse effects on survival. J Surg Oncol, 2018, 117(6): 1267-1277.
27. Hirano S, Tanaka E, Tsuchikawa T, et al. Oncological benefit of preoperative endoscopic biliary drainage in patients with hilar cholangiocarcinoma. J Hepatobiliary Pancreat Sci, 2014, 21(8): 533-540.
28. Al Mahjoub A, Menahem B, Fohlen A, et al. Preoperative biliary drainage in patients with resectable perihilar cholangiocarcinoma: is percutaneous transhepatic biliary drainage safer and more effective than endoscopic biliary drainage? A meta-analysis. J Vasc Interv Radiol, 2017, 28(4): 576-582.
29. Tang Z, Yang Y, Meng W, et al. Best option for preoperative biliary drainage in Klatskin tumor: A systematic review and meta-analysis. Medicine (Baltimore), 2017, 96(43): e8372.
30. Liu JG, Wu J, Wang J, et al. Endoscopic biliary drainage versus percutaneous transhepatic biliary drainage in patients with resectable hilar cholangiocarcinoma: a systematic review and meta-analysis. J Laparoendosc Adv Surg Tech, 2018, 28(9): 1053-1060.
31. Hameed A, Pang T, Chiou J, et al. Percutaneous vs. endoscopic pre-operative biliary drainage in hilar cholangiocarcinoma-a systematic review and meta-analysis. HPB (Oxford), 2016, 18(5): 400-410.
32. Wang C, Xu Y, Lu X. Should preoperative biliary drainage be routinely performed for obstructive jaundice with resectable tumor? Hepatobiliary Surg Nutr, 2013, 2(5): 266-271.
33. Jo JH, Chung MJ, Han DH, et al. Best options for preoperative biliary drainage in patients with Klatskin tumors. Surg Endosc, 2017, 31(1): 422-429.
34. Kawakami H, Kuwatani M, Onodera M, et al. Endoscopic nasobiliary drainage is the most suitable preoperative biliary drainage method in the management of patients with hilar cholangiocarcinoma. J Gastroenterol, 2011, 46(2): 242-248.
35. Higuchi R, Yazawa T, Uemura S, et al. ENBD is associated with decreased tumor dissemination compared to PTBD in perihilar cholangiocarcinoma. J Gastrointest Surg, 2017, 21(9): 1506-1514.
36. 張輝, 張振, 張海濤, 等. 肝門部膽管癌根治術前經內鏡鼻膽管引流和經皮經肝膽管造影引流術的臨床效果觀察. 腹部外科, 2017, 30(3): 197-201.
37. Kang MJ, Choi YS, Jang JY, et al. Catheter tract recurrence after percutaneous biliary drainage for hilar cholangiocarcinoma. World J Surg, 2013, 37(2): 437-442.
38. Paik WH, Loganathan N, Hwang JH. Preoperative biliary drainage in hilar cholangiocarcinoma: when and how? World J Gastrointest Endosc, 2014, 6(3): 68-73.
39. Komaya K, Ebata T, Yokoyama Y, et al. Verification of the oncologic inferiority of percutaneous biliary drainage to endoscopic drainage: a propensity score matching analysis of resectable perihilar cholangiocarcinoma. Surgery, 2017, 161(2): 394-404.

Previous Article
The clinical application of everolimus after liver transplantation for hepatocellular carcinoma
Next Article
Research progress on pancreatic cancer-associated diseases

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Controversy of preoperative biliary drainage for resectable hilar cholangiocarcinoma

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content