Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection <i>versus</i> pancreaticoduodenectomy: a single center experience_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

CHENG Kun ¹ , SUN Yonghui ¹ , LIN Hai ¹ , DING Nan ² , XU Jiaqi ¹ ,  CHEN Qilong ¹

1. Department of Pancreas Surgery, Digestion and Vascular Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P. R. China;
2. Department of Pharmacy, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P. R. China;

Corresponding?author：

CHEN Qilong, Email: chenqilong651003@sohu.com

Keywords：

duodenum-preserving pancreatic head resection; pancreaticoduodenectomy; chronic pancreatitis; pancreatic tumor

DOI：

10.7507/1007-9424.201912113

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize and analyze the long-term clinical effect of duodenum-preserving pancreatic head resection (DPPHR) versus pancreaticoduodenectomy.Methods The clinical data of 102 patients who underwent DPPHR (n=35) or pancreaticoduodenectomy (n=67) from January 2014 to December 2019 in The First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively.Results The operations of patients in the DPPHR group and the PD group were successfully complete, no one died during operation or perioperative period. The weight gain in one year after operation and incidences of exocrine dysfunction in the DPPHR group were all better than those of the PD group (P<0.05), but there was no significant difference on the other complications between the two groups (P>0.05). The pain score, diarrhea score, and the overall health status score in one year after operation significantly improved in the DPPHR group than those in the PD group (P<0.05).Conclusion DPPHR is more beneficial to improve the quality of life after operation, and is a better surgical procedure for benign and low-grade malignant diseases of pancreatic head.

Citation： CHENG Kun, SUN Yonghui, LIN Hai, DING Nan, XU Jiaqi, CHEN Qilong. Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection versus pancreaticoduodenectomy: a single center experience. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2020, 27(10): 1211-1215. doi: 10.7507/1007-9424.201912113 Copy

1.	Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of vater. Ann Surg, 1935, 102(4): 763-779.
2.	Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin, 2019, 69(1): 7-34.
3.	Narayanan S, Martin AN, Turrentine FE, <italic>et al</italic>. Mortality after pancreaticoduodenectomy: assessing early and late causes of patient death. J Surg Res, 2018, 231: 304-308.
4.	Morales Soriano R, Esteve Pérez N, Tejada Gavela S, <italic>et al</italic>. Outcomes of an enhanced recovery after surgery programme for pancreaticoduodenectomy. Cir Esp, 2015, 93(8): 509-515.
5.	Beger HG, Krautzberger W, Bittner R, <italic>et al</italic>. Duodenum-preserving resection of the head of the pancreas in patients with severe chronic pancreatitis. Surgery, 1985, 97(4): 467-473.
6.	Gloor B, Friess H, Uhl W, <italic>et al</italic>. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis. Dig Surg, 2001, 18(1): 21-25.
7.	Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology, 1993, 40(4): 356-359.
8.	Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Complete duodenum-preserving resection of the head of the pancreas with preservation of the biliary tract. J Hep Bil Panc Surg, 1995, 2(1): 32-37.
9.	Imaizumi T, Hanyu F, Suzuki M. A new procedure for duodenum-preserving total resection of the head of the pancreas with pancreaticocholedochoduodenostomy. Stand Panc Surg, 1993: 464-470.
10.	孫永輝, 程坤, 陳啟龍. 保留十二指腸胰頭切除術的臨床應用及進展. 中國普外基礎與臨床雜志, 2019, 26(10): 1259-1264.
11.	張太平, 曹喆, 趙玉沛. 慢性胰腺炎合并胰頭腫塊的外科治療策略. 中國普外基礎與臨床雜志, 2016, 23(6): 644-646.
12.	劉續寶. 慢性胰腺炎的胰頭炎性包塊的外科治療. 中國普外基礎與臨床雜志, 2013, 20(2): 121-123.
13.	Beger HG. Benign tumors of the pancreas-radical surgery <italic>versus</italic> parenchyma-sparing local resection-the challenge facing surgeons. J Gastrointest Surg, 2018, 22(3): 562-566.
14.	Strobel O, Büchler MW. Pancreatoduodenectomy <italic>vs</italic> duodenum-preserving pancreatic head resection for chronic pancreatitis. Chirurg, 2019, 90(Suppl 2): 77.
15.	Beger HG, Mayer B, Poch B. Duodenum-preserving pancreatic head resection: a local parenchyma-sparing treatment of benign and premalignant tumors of the pancreatic head. Chirurg, 2019, 90(9): 736-743.
16.	Ayres Pereira M, Chio IIC. Metastasis in pancreatic ductal adenocarcinoma: current standing and methodologies. Genes (Basel), 2019, 11(1): E6.
17.	Diener MK, Hüttner FJ, Kieser M, <italic>et al</italic>. Partial pancreatoduodenectomy <italic>versus</italic> duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet, 2017, 390(10099): 1027-1037.
18.	董志毅. 保留十二指腸的胰頭切除術在胰頭部良性病變中的應用及對術后生活質量的影響研究. 中華普外科手術學雜志 (電子版), 2017, 11(6): 528-530.
19.	洪德飛, 林志川, 張宇華, 等. 保留十二指腸和膽管完整性胰頭切除術 31 例報告. 中華肝膽外科雜志, 2017, 23(3): 176-180.
20.	劉翔琪, 董巋然, 柳龔堡, 等. 保留十二指腸胰頭腫塊切除術在兒童胰頭腫瘤治療中的應用. 中華小兒外科雜志, 2017, 38(2): 103-106.
21.	王金湖, 茅君卿, 蔡嘉斌, 等. 保留十二指腸的胰頭腫瘤切除術在兒童胰頭腫瘤治療中的應用. 浙江醫學, 2019, 41(18): 1989-1991, 前插 5.
22.	Beger HG, Nakao A, Mayer B, <italic>et al</italic>. Duodenum-preserving total and partial pancreatic head resection for benign tumors–systematic review and meta-analysis. Pancreatology, 2015, 15(2): 167-178.
23.	孫永輝, 張曉晶, 林海, 等. 保留十二指腸的胰頭切除術與胰十二指腸切除術治療慢性胰腺炎療效的 Meta 分析. 中華內分泌外科雜志, 2019, 13(3): 249-255.
24.	Zhao X, Cui N, Wang X, <italic>et al</italic>. Surgical strategies in the treatment of chronic pancreatitis: an updated systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore), 2017, 96(9): e6220.
25.	李建國, 王淵全, 陳譚根, 等. 保留十二指腸和膽管的胰頭全切除術. 中華消化外科雜志, 2014, 13(11): 898-901.

1. Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of vater. Ann Surg, 1935, 102(4): 763-779.
2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin, 2019, 69(1): 7-34.
3. Narayanan S, Martin AN, Turrentine FE, <italic>et al</italic>. Mortality after pancreaticoduodenectomy: assessing early and late causes of patient death. J Surg Res, 2018, 231: 304-308.
4. Morales Soriano R, Esteve Pérez N, Tejada Gavela S, <italic>et al</italic>. Outcomes of an enhanced recovery after surgery programme for pancreaticoduodenectomy. Cir Esp, 2015, 93(8): 509-515.
5. Beger HG, Krautzberger W, Bittner R, <italic>et al</italic>. Duodenum-preserving resection of the head of the pancreas in patients with severe chronic pancreatitis. Surgery, 1985, 97(4): 467-473.
6. Gloor B, Friess H, Uhl W, <italic>et al</italic>. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis. Dig Surg, 2001, 18(1): 21-25.
7. Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology, 1993, 40(4): 356-359.
8. Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Complete duodenum-preserving resection of the head of the pancreas with preservation of the biliary tract. J Hep Bil Panc Surg, 1995, 2(1): 32-37.
9. Imaizumi T, Hanyu F, Suzuki M. A new procedure for duodenum-preserving total resection of the head of the pancreas with pancreaticocholedochoduodenostomy. Stand Panc Surg, 1993: 464-470.
10. 孫永輝, 程坤, 陳啟龍. 保留十二指腸胰頭切除術的臨床應用及進展. 中國普外基礎與臨床雜志, 2019, 26(10): 1259-1264.
11. 張太平, 曹喆, 趙玉沛. 慢性胰腺炎合并胰頭腫塊的外科治療策略. 中國普外基礎與臨床雜志, 2016, 23(6): 644-646.
12. 劉續寶. 慢性胰腺炎的胰頭炎性包塊的外科治療. 中國普外基礎與臨床雜志, 2013, 20(2): 121-123.
13. Beger HG. Benign tumors of the pancreas-radical surgery <italic>versus</italic> parenchyma-sparing local resection-the challenge facing surgeons. J Gastrointest Surg, 2018, 22(3): 562-566.
14. Strobel O, Büchler MW. Pancreatoduodenectomy <italic>vs</italic> duodenum-preserving pancreatic head resection for chronic pancreatitis. Chirurg, 2019, 90(Suppl 2): 77.
15. Beger HG, Mayer B, Poch B. Duodenum-preserving pancreatic head resection: a local parenchyma-sparing treatment of benign and premalignant tumors of the pancreatic head. Chirurg, 2019, 90(9): 736-743.
16. Ayres Pereira M, Chio IIC. Metastasis in pancreatic ductal adenocarcinoma: current standing and methodologies. Genes (Basel), 2019, 11(1): E6.
17. Diener MK, Hüttner FJ, Kieser M, <italic>et al</italic>. Partial pancreatoduodenectomy <italic>versus</italic> duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet, 2017, 390(10099): 1027-1037.
18. 董志毅. 保留十二指腸的胰頭切除術在胰頭部良性病變中的應用及對術后生活質量的影響研究. 中華普外科手術學雜志 (電子版), 2017, 11(6): 528-530.
19. 洪德飛, 林志川, 張宇華, 等. 保留十二指腸和膽管完整性胰頭切除術 31 例報告. 中華肝膽外科雜志, 2017, 23(3): 176-180.
20. 劉翔琪, 董巋然, 柳龔堡, 等. 保留十二指腸胰頭腫塊切除術在兒童胰頭腫瘤治療中的應用. 中華小兒外科雜志, 2017, 38(2): 103-106.
21. 王金湖, 茅君卿, 蔡嘉斌, 等. 保留十二指腸的胰頭腫瘤切除術在兒童胰頭腫瘤治療中的應用. 浙江醫學, 2019, 41(18): 1989-1991, 前插 5.
22. Beger HG, Nakao A, Mayer B, <italic>et al</italic>. Duodenum-preserving total and partial pancreatic head resection for benign tumors–systematic review and meta-analysis. Pancreatology, 2015, 15(2): 167-178.
23. 孫永輝, 張曉晶, 林海, 等. 保留十二指腸的胰頭切除術與胰十二指腸切除術治療慢性胰腺炎療效的 Meta 分析. 中華內分泌外科雜志, 2019, 13(3): 249-255.
24. Zhao X, Cui N, Wang X, <italic>et al</italic>. Surgical strategies in the treatment of chronic pancreatitis: an updated systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore), 2017, 96(9): e6220.
25. 李建國, 王淵全, 陳譚根, 等. 保留十二指腸和膽管的胰頭全切除術. 中華消化外科雜志, 2014, 13(11): 898-901.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection versus pancreaticoduodenectomy: a single center experience

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content