Application of <i>ex vivo</i> liver resection and autotransplantation in hepatobiliary diseases_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

DONG Xiaoge ¹ , WANG Zhan ² , YUAN Jiaqi ² , LIU Haigang ¹ , DU Kaihao ¹ , ZHANG Shuai ¹ ,  HOU Lizhao ²

1. Qinghai University Clinical Medical College, Xining 810001, P. R. China;
2. Department of General Surgery, Affiliated Hospital of Qinghai University, Xining 810001, P. R. China;

Corresponding?author：

HOU Lizhao, Email: zhuoyue_1973@163.com

Keywords：

ex vivo liver resection; autotransplantation; hepatic alveolar echinococcosis; liver cancer; cholangiocarcinoma

DOI：

10.7507/1007-9424.202405064

Video：

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Objective To summarize and analyze the application of ex vivo liver resection and autotransplantation (ELRA) in the treatment of hepatobiliary diseases. Method The related literature about ELRA used to treat various hepatobiliary space-occupyingdiseases at home and abroad in recent years was comprehensively searched and summarized. Results ELRA had overcome the limitations of limited operational space in traditional surgery for the treatment of hepatobiliary space-occupying diseases reduced dependence on donor livers, and avoided post-transplant rejection. It had been applied in the treatment of hepatic alveolar echinococcosis, liver cancer, cholangiocarcinoma, and rare liver space-occupying diseases. Conclusions With the maturation of ELRA techniques and the continuous improvement of ex vivo liver perfusion technology, along with rigorous preoperative evaluation and meticulous postoperative management, postoperative complications of ELRA have significantly decreased compared to the initial stages of its application. By strictly adhering to surgical indications, this procedure is expected to be used treatment in an increasing number of hepatobiliary space-occupying diseases.

Citation： DONG Xiaoge, WANG Zhan, YUAN Jiaqi, LIU Haigang, DU Kaihao, ZHANG Shuai, HOU Lizhao. Application of ex vivo liver resection and autotransplantation in hepatobiliary diseases. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2024, 31(10): 1265-1271. doi: 10.7507/1007-9424.202405064 Copy

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CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Application of ex vivo liver resection and autotransplantation in hepatobiliary diseases

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