LI Ling 1,2 , HUANG Jing 1,2 , XU Jing 1,2 , MA Yukui 1 , WU Zhoupeng 1
  • 1. Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 2. West China School of Nursing, Sichuan University, Chengdu 610041, P. R. China;
WU Zhoupeng, Email: lzwzp19@163.com
venous thromboembolism; prognostic nutritional index; mortality; predictive factor; nutritional assessment
10.7507/1007-9424.202506139
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Objective This study aims to evaluate the prognostic nutritional index (PNI) as a predictor of 2-year mortality risk in patients with venous thromboembolism (VTE). Methods We conducted a retrospective analysis of clinical data from VTE patients admitted to the Department of Vascular Surgery at West China Hospital of Sichuan University between January 2020 and June 2024. Patients received either 3 or 6 months anticoagulant therapy. Results A total of 260 VTE patients were included, categorized into mortality group (n=26) and non-mortality group (n=234) based on whether live or dead in 2 years after discharge. Compare to non-mortality group, the mortality group had a higher prevalence of old-age, nutritional risk and VTE recurrence, and lower PNI level (P<0.05). Multivariable Cox proportional hazards regression analysis identified PNI<36.8 [RR=8.579, P<0.001], VTE recurrence [RR=2.648, P=0.019], old-age [RR=3.931, P=0.001], and combined hypertension [RR=2.783, P=0.038] as independent mortality risk factors in VTE patients. Conclusions The PNI is significantly negatively correlated with mortality risk in VTE patients. It serves as a valuable tool for clinicians to identify VTE patients at high risk of death early in their treatment.

Citation： LI Ling, HUANG Jing, XU Jing, MA Yukui, WU Zhoupeng. Association between the prognostic nutritional index and 2-year mortality in patients with venous thromboembolism. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2026, 33(2): 221-225. doi: 10.7507/1007-9424.202506139 Copy

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