Clinical efficacy of using respiratory humidification apparatus (AIRVO<sub>2</sub>) in patients with tracheotomy after successful weaning from mechanical ventilation_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

LI Bing ¹ , YANG Yuanli ¹ , JIA Yeran ² , CAO Feng ¹ , CHEN Ronglin ¹ ,  ZHANG Hongxuan ²

1. Department of Critical Care Medicine, Longgang Central Hospital of Shenzhen City, Shenzhen, Guangdong 518116, P. R. China;
2. Eastern Section, Guangdong General Hospital, Guangdong Institute of Geriatrics, Guangzhou, Guangdong 510180, P. R. China;

Corresponding?author：

ZHANG Hongxuan, Email: 13602816365@139.com

Keywords：

Tracheotomy; Weaning from mechanical ventilation; Respiratory humidification treatment apparatus; Clinical efficacy

DOI：

10.7507/1671-6205.201807028

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Objective To investigate the clinical efficacy of AIRVO₂ respiratory humidification apparatus in patients with tracheotomy after successful weaning from mechanical ventilation in intensive care unit (ICU).Methods One hundred subjects were randomly divided into a control group (treated with the tracheotomy mask joint oxygen inhalation by heating humidifier, n=50) and an observation group (treated with AIRVO₂ model, n=50) on the basis of conventional therapy. Blood gas indexes (pH, PaO₂, PaCO₂, PaO₂/FiO₂) and clinical data (heart rate, respiratory rate, SpO₂, sputum viscosity) were recorded at 0 h, 6 h, 12 h, 24 h, 48 h, 72 h after weaning. Besides, the incidence of postoperative pulmonary infection, rapid shallow breathing index (RSBI), successful weaning rate from mechanical ventilation and daily cost of weaning between the two groups were compared at 72 h after weaning.Results After treatment, all observed data of the patients were obviously improved compared with those before treatment. The differences of humidification effects between the observation group and the control group at the same time point were statistically significant (P<0.05). The differences of heart rate, respiratory rate, and SpO₂ between the observation group and the control group at the same time point were statistically significant (P<0.05). The improvement of PaO₂ and PaCO₂ at the same time point were statistically different between the observation group and the control group (P<0.05). Seventy-two hours after weaning, the incidence of postoperative pulmonary infection and RSBI in the observation group were significantly lower than those in the control group (P<0.05), successful weaning rate from mechanical ventilation in the observation group was significantly higher than that in the control group (P<0.05), and the average daily cost of weaning from mechanical ventilation in the observation group was lower than that in the control group (P<0.05). Nine patients in the control group and 1 patient in the observation group needed secondary mechanical ventilation due to hypoxemia.Conclusion The therapy of AIRVO₂ respiratory humidification apparatus combined with conventional treatment may achieve satisfactory effect for patients of successful weaning from mechanical ventilation with tracheotomy, and it is worthy of promotion in clinical use.

Citation： LI Bing, YANG Yuanli, JIA Yeran, CAO Feng, CHEN Ronglin, ZHANG Hongxuan. Clinical efficacy of using respiratory humidification apparatus (AIRVO₂) in patients with tracheotomy after successful weaning from mechanical ventilation. Chinese Journal of Respiratory and Critical Care Medicine, 2019, 18(1): 37-41. doi: 10.7507/1671-6205.201807028 Copy

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15.	黃維明, 謝春雷, 李春霞, 等. 神經外科重癥監護病房氣管切開患者肺部感染的目標性監測和干預. 中華現代護理雜志, 2011, 17(32): 3911-3913.
16.	郭潤玲, 郭愛芝, 王穎, 等. Venturi+MR50 氧療在氣管插管患者拔管中的應用. 護理研究, 2014, 7(7C): 2636-2637.
17.	趙彥卓, 魏瓊. 呼吸濕化治療儀在氣管插管患者脫機后的應用. 臨床誤診誤治, 2016, 29(S1): 100-101.
18.	李威, 吳迪迪, 黃思語. 機械通氣患者脫機后應用 IRVO₂ 呼吸濕化治療儀、Stellar100 無創呼吸機療效觀察. 新疆醫學, 2017, 47(5): 492-494.

1. 沈海芬, 張海英. 腦外傷患者氣管切開后不同黏稠度痰液適宜吸痰負壓的臨床研究. 中華護理雜志, 2009, 44(8): 694-697.
2. 賴士群, 伍雪艷, 梁偉霞, 等. 吸入性損傷氣管切開病人吸痰方法探討. 護理研究, 2010, 24(19): 1721-1722.
3. 單亮. 氣管切開時機對危重患者臨床預后影響的 meta 分析. 濟南: 山東大學, 2013.
4. 陳元杰, 孫琳, 彭琳, 等. 高流量濕化氧對危重患者脫機后呼吸功能的保護作用. 中國呼吸與危重監護雜志, 2018, 17(3): 259-262.
5. 燕朋波, 全金梅, 李志靜, 等. 三種不同氣道濕化方法對建立人工氣道脫機患者效果研究. 中國呼吸與危重監護雜志, 2014, 13(5): 480-483.
6. 白二靈. 淺談氣管切開術后的護理體會. 世界最新醫學信息文摘, 2015, 15(19): 152-153.
7. Sztrymf B, Messika J, Bertrand F, et al. Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med, 2011, 37(11): 1780-1786.
8. Sztrymf B, Messika J, Mayot T, et al. Impact of high-flow nasal cannula oxygen therapy on intensive care unit patients with acute respiratory failure: a prospective observational study. J Crit Care, 2012, 27(3): 324.
9. Lenglet H, Sztrymf B, Leroy C, et al. Humidified high flow nasal oxygen in the emergency department: feasibility and interest. Respiratory Care, 2012, 57(11): 1873-1878.
10. 藍惠蘭, 鄧旭萍, 陳瀚熙, 等. 機械通氣呼吸濕化器濕化研究進展. 護理學雜志, 2013, 28(13): 94-97.
11. 肖凌月. 人工鼻和呼吸機濕化器用于經人工氣道行機械輔助通氣病人的臨床研究. 護理研究, 2010, 24(1): 209-210.
12. 江方正, 李雪, 葉向紅, 等. 持續加溫濕化氧療在氣管切開患者脫機中的應用. 中華護理雜志, 2011, 46(2): 128-130.
13. 姜超美, 白淑玲, 王辰, 等. 人工氣道后痰液黏稠度的判別方法及臨床意義. 中華護理雜志, 1994, 29(7): 434.
14. 中華人民共和國衛生部. 醫院感染診斷標準(試行). 中華醫院感染雜志, 2001, 36(8): 495.
15. 黃維明, 謝春雷, 李春霞, 等. 神經外科重癥監護病房氣管切開患者肺部感染的目標性監測和干預. 中華現代護理雜志, 2011, 17(32): 3911-3913.
16. 郭潤玲, 郭愛芝, 王穎, 等. Venturi+MR50 氧療在氣管插管患者拔管中的應用. 護理研究, 2014, 7(7C): 2636-2637.
17. 趙彥卓, 魏瓊. 呼吸濕化治療儀在氣管插管患者脫機后的應用. 臨床誤診誤治, 2016, 29(S1): 100-101.
18. 李威, 吳迪迪, 黃思語. 機械通氣患者脫機后應用 IRVO₂ 呼吸濕化治療儀、Stellar100 無創呼吸機療效觀察. 新疆醫學, 2017, 47(5): 492-494.

Chinese Journal of Respiratory and Critical Care Medicine

Clinical efficacy of using respiratory humidification apparatus (AIRVO₂) in patients with tracheotomy after successful weaning from mechanical ventilation

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Chinese Journal of Respiratory and Critical Care Medicine

Clinical efficacy of using respiratory humidification apparatus (AIRVO2) in patients with tracheotomy after successful weaning from mechanical ventilation

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Clinical efficacy of using respiratory humidification apparatus (AIRVO₂) in patients with tracheotomy after successful weaning from mechanical ventilation