結核分枝桿菌耐異煙肼診斷試驗的系統評價_《中國循證醫學雜志》

作者：

張君雨 ¹ , 田金徽 ² , 姜雷 ² , 張穎 ³⁴ , 楊孫虎 ² , 于紅娟 ³ ,  楊克虎 ²

1. 甘肅省疾病預防控制中心（蘭州 730001）；2. 蘭州大學循證醫學中心（蘭州 730000）；3. 蘭州大學結核病研究中心（蘭州 730000)；4. 美國霍普金斯大學隆博格公共衛生學院（華盛頓 074100）;

關鍵詞：

結核分枝桿菌異煙肼診斷性試驗系統評價

DOI：

10.7507/1672-2531.20080192

視頻：

導出 下載 收藏 掃碼 引用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

目的　評價9 種檢測結核分枝桿菌耐異煙肼診斷試驗方法的準確性。
方法　計算機檢索PubMed、EMbase等數據庫和手工檢索相關期刊，全面收集結核分枝桿菌耐異煙肼診斷試驗的研究，依據QUADAS評價納入診斷試驗的質量，并對結果進行Meta 分析。
結果　最終納入12 個研究。Meta分析結果顯示：硝酸鹽還原法與比例法相比，以及BACTEC MGIT 960 與BACTEC 460 TB相比，其敏感度、特異度、陽性似然比、陰性似然比及SROC曲線下面積分別為92%、99%、31.84、0.12、0.983 6和98.5%、96%、13.66、0.035、0.987 1；其余檢測方法，如MODS、MB/BacT、MYDBA 和TTC亦顯示了較好的敏感度和特異度。
結論　硝酸鹽還原檢測法可代替比例法作為結核分枝桿菌耐異煙肼的篩查試驗。BACTEC MGIT 960可代替BACTEC 460檢測系統作為結核分枝桿菌耐異煙肼的確診試驗。

引用本文： 張君雨,田金徽,姜雷,張穎,楊孫虎,于紅娟,楊克虎. 結核分枝桿菌耐異煙肼診斷試驗的系統評價. 中國循證醫學雜志, 2008, 08(10): 869-874. doi: 10.7507/1672-2531.20080192 復制

1.	世界衛生組織, 關于結核病的10個事實[EB/OL]. (2007-03-22) [2007-8-10]. http://www.who.int/features/factfiles/tuberculosis/zh/index.html.
2.	The WHO/IUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance: Anti-Tuberculosis drug resistance in the world, report number 2 Volume. Geneva; 2004.
3.	全國結核病流行病學抽樣調查技術指導組, 全國結核病流行病學抽樣調查辦公室. 2000年全國結核病流行病學抽樣調查報告, 中國防癆雜志, 2002, 24: 65-108.
4.	世界衛生組織, 結核病診斷: 全球需求與市場潛力, [ EB/OL](2006-10-25) [2007-8-10],http://bioop.comdedecms3/html/shengwuqianyan/2006/1028/13557.html.
5.	Whiting P, Rutjes AW, Reitsma JB, et al. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol, 2003, 3: 25.
6.	Musa HR, Ambroggi M, Souto A, et al. Drug susceptibility testing of mycobacterium tuberculosis by a nitrate reductase assay applied directly on microscopy-positive sputum samples. Journal of Clinical Microbiology, 2005, 43(7): 3159-3161.
7.	Martin A,Montoro E, Lemus D, et al. Multicenter evaluation of the nitrate reductase assay for drug resistance detection of Mycobacterium tuberculosis. Journal of Microbiological Methods, 2005, 63: 145-150.
8.	Lemus D, Montoro E, Echemend?′a M, et al. Nitrate reductase assay for detection of drug resistance in Mycobacterium tuberculosis: simple and inexpensive method for low-resource laboratories. Journal of Microbiological Methods, 2006, 55: 861-863.
9.	Shiferaw G, Woldeamanuel Y, Mekdes G, et al. Evaluation of microscopic observation drug susceptibility assay for detection of multidrug-resistant mycobacterium tuberculosis. Journal of Clinical Microbiology, 2007, 45(4): 1093-1097.
10.	Mohammadzadeh A, Farnia P, Ghazvini K, et al. Rapid and lowcost colorimetric method using 2,3,5-triphenyltetrazolium chloride for detection of multidrug-resistant mycobacterium tuberculosis. Journal of clinical microbiology, 2006, 55: 1657-1659.
11.	Chauca JA, Palomino JC, Guerra H. Evaluation of rifampicin and isoniazid susceptibility testing of mycobacterium tuberculosis by a mycobacteriophage D29-based assay. Eur J Clin Microbiol Infect Dis, 2007, 56: 360-364.
12.	Cambau E, Truffot-Pernot C, Boulahbal F, et al. Mycobacterial growth indicator tube versus the proportion method on l?wensteinjensen medium for antibiotic susceptibility testing of mycobacterium tuberculosis. Eur J Clin Microbiol Infect Dis, 2000, 19: 938-942.
13.	Telles MAS, Bori A, Amorim ABR, et al. Rapid detection of multidrug-resistant mycobacterium tuberculosis using the mycobacteria growth indicator tube (MGIT) system. Brazilian Journal of Medical and Biological Reaserch, 2002, 35: 1127-1131.
14.	Adjers-Koskela K, Katila ML. Susceptibility testing with the manual mycobacteria growth indicator tube (MGIT) and the MGIT 960 system provides rapid and reliable verification of multidrugresistant tuberculosis. Journal of Clinical Microbiology, 2003, 41(3): 1235-1239.
15.	Garrigó M, Marcela Aragón L, Alcaide F, et al. Multicenter laboratory evaluation of the MB/BacT mycobacterium detection system and the BACTEC MGIT 960 system in comparison with the BACTEC 460TB system for susceptibility testing of mycobacterium tuberculosis. Journal of Clinical Microbiology, 2007, 45(6): 1766-1770.
16.	Bemer P, Palicova F, Ru¨sch-Gerdes S, et al. Multicenter Evaluation of Fully Automated BACTEC Mycobacteria Growth Indicator Tube 960 System for Susceptibility Testing of Mycobacterium tuberculosis. Journal of Clinical Microbiology, 2002, 40(1): 150-154.
17.	卿克勤, 秦進, 周小平. BACTECMGIT960系統結核分枝桿菌藥物敏感測定功能評價. 華西醫學, 2004, 19(2): 203-204.
18.	?ngeby KAK, Klintz L, Hoffner SE, et al. Rapid and inexpensive drug susceptibility teasting of mycobacterium tuberculosis with Nitrate Reductase Assay. J Clin Microbio1. 2002, 40(2): 553-555.
19.	劉宇紅, 王蘇民, 那希寬. 比例法測試結核分枝桿菌藥物敏感性的探討. 中國防癆雜志, 2002, (2): 89-92.

1. 世界衛生組織, 關于結核病的10個事實[EB/OL]. (2007-03-22) [2007-8-10]. http://www.who.int/features/factfiles/tuberculosis/zh/index.html.
2. The WHO/IUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance: Anti-Tuberculosis drug resistance in the world, report number 2 Volume. Geneva; 2004.
3. 全國結核病流行病學抽樣調查技術指導組, 全國結核病流行病學抽樣調查辦公室. 2000年全國結核病流行病學抽樣調查報告, 中國防癆雜志, 2002, 24: 65-108.
4. 世界衛生組織, 結核病診斷: 全球需求與市場潛力, [ EB/OL](2006-10-25) [2007-8-10],http://bioop.comdedecms3/html/shengwuqianyan/2006/1028/13557.html.
5. Whiting P, Rutjes AW, Reitsma JB, et al. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol, 2003, 3: 25.
6. Musa HR, Ambroggi M, Souto A, et al. Drug susceptibility testing of mycobacterium tuberculosis by a nitrate reductase assay applied directly on microscopy-positive sputum samples. Journal of Clinical Microbiology, 2005, 43(7): 3159-3161.
7. Martin A,Montoro E, Lemus D, et al. Multicenter evaluation of the nitrate reductase assay for drug resistance detection of Mycobacterium tuberculosis. Journal of Microbiological Methods, 2005, 63: 145-150.
8. Lemus D, Montoro E, Echemend?′a M, et al. Nitrate reductase assay for detection of drug resistance in Mycobacterium tuberculosis: simple and inexpensive method for low-resource laboratories. Journal of Microbiological Methods, 2006, 55: 861-863.
9. Shiferaw G, Woldeamanuel Y, Mekdes G, et al. Evaluation of microscopic observation drug susceptibility assay for detection of multidrug-resistant mycobacterium tuberculosis. Journal of Clinical Microbiology, 2007, 45(4): 1093-1097.
10. Mohammadzadeh A, Farnia P, Ghazvini K, et al. Rapid and lowcost colorimetric method using 2,3,5-triphenyltetrazolium chloride for detection of multidrug-resistant mycobacterium tuberculosis. Journal of clinical microbiology, 2006, 55: 1657-1659.
11. Chauca JA, Palomino JC, Guerra H. Evaluation of rifampicin and isoniazid susceptibility testing of mycobacterium tuberculosis by a mycobacteriophage D29-based assay. Eur J Clin Microbiol Infect Dis, 2007, 56: 360-364.
12. Cambau E, Truffot-Pernot C, Boulahbal F, et al. Mycobacterial growth indicator tube versus the proportion method on l?wensteinjensen medium for antibiotic susceptibility testing of mycobacterium tuberculosis. Eur J Clin Microbiol Infect Dis, 2000, 19: 938-942.
13. Telles MAS, Bori A, Amorim ABR, et al. Rapid detection of multidrug-resistant mycobacterium tuberculosis using the mycobacteria growth indicator tube (MGIT) system. Brazilian Journal of Medical and Biological Reaserch, 2002, 35: 1127-1131.
14. Adjers-Koskela K, Katila ML. Susceptibility testing with the manual mycobacteria growth indicator tube (MGIT) and the MGIT 960 system provides rapid and reliable verification of multidrugresistant tuberculosis. Journal of Clinical Microbiology, 2003, 41(3): 1235-1239.
15. Garrigó M, Marcela Aragón L, Alcaide F, et al. Multicenter laboratory evaluation of the MB/BacT mycobacterium detection system and the BACTEC MGIT 960 system in comparison with the BACTEC 460TB system for susceptibility testing of mycobacterium tuberculosis. Journal of Clinical Microbiology, 2007, 45(6): 1766-1770.
16. Bemer P, Palicova F, Ru¨sch-Gerdes S, et al. Multicenter Evaluation of Fully Automated BACTEC Mycobacteria Growth Indicator Tube 960 System for Susceptibility Testing of Mycobacterium tuberculosis. Journal of Clinical Microbiology, 2002, 40(1): 150-154.
17. 卿克勤, 秦進, 周小平. BACTECMGIT960系統結核分枝桿菌藥物敏感測定功能評價. 華西醫學, 2004, 19(2): 203-204.
18. ?ngeby KAK, Klintz L, Hoffner SE, et al. Rapid and inexpensive drug susceptibility teasting of mycobacterium tuberculosis with Nitrate Reductase Assay. J Clin Microbio1. 2002, 40(2): 553-555.
19. 劉宇紅, 王蘇民, 那希寬. 比例法測試結核分枝桿菌藥物敏感性的探討. 中國防癆雜志, 2002, (2): 89-92.

《中國循證醫學雜志》

結核分枝桿菌耐異煙肼診斷試驗的系統評價

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

《中國循證醫學雜志》

結核分枝桿菌耐異煙肼診斷試驗的系統評價

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料