Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review_Chinese Journal of Evidence-Based Medicine

Authors：

 LIXiao-su ¹ , LIURu-ming ¹ , WANGLu-jie ¹ , ZHANGJun ¹ , ZHANGLing-li ^2,3 ,  LIYou-ping ⁴ , SONGJie ^2,3

1. Clinical Pharmacy Department, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China;
2. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
3. Evidence-based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
4. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding?author：

LIYou-ping, Email: zhangjunyang@126.com

Keywords：

Children; Juvenile idiopathic arthritis; Evidence-based guideline; Systematic review

DOI：

10.7507/1672-2531.20150027

Video：

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Objective To systematically assess the quality of evidence-based clinical guidelines on the treatment of children with juvenile idiopathic arthritis and to compare the differences and similarities between recommendations, so as to provide references for clinical application. Methods Databases such as the TRIP, PubMed, CNKI, VIP, WanFang Data, CBM, U.S National Guideline Clearinghouse and Guidelines International Network were searched to collect evidencebased guidelines on medication therapy for children with juvenile idiopathic arthritis. Methodological quality of included guidelines was assessed according to the AGREE Ⅲ instrument, and differences and similarities among recommendations were compared. Results Two evidence-based clinical guidelines from Australia and China were included. Among 6 domains of the Australian guideline which were rated using AGREE Ⅲ instrument, "scope and purpose", "stakeholder involvement", "rigor of development", "clarity and presentation", "applicability" and "editorial independence" were scored more than 50%. As for Chinese guideline, "scope and purpose", "stakeholder involvement", "rigor of development", "clarity and presentation" and "editorial independence" was all scored more than 50%, but "applicability" was scored less than 50%. Conclusion The included guidelines are of high quality and strongly recommended, but the recommendations might exist limitation for Chinese children. Thus, the development of relevant Chinese evidence-based guidelines are urgently needed.

Citation： LIXiao-su, LIURu-ming, WANGLu-jie, ZHANGJun, ZHANGLing-li, LIYou-ping, SONGJie. Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2015, 15(2): 152-158. doi: 10.7507/1672-2531.20150027 Copy

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2.	《中華兒科雜志》編輯委員會, 中華醫學會兒科學分會免疫學組. 幼年特發性關節炎(多/少關節型)診療建議. 中華兒科雜志,2012, 50(1):20-26.
3.	National Health and Medical Research Council. Clinical guideline for the diagnosis and management of juvenile idiopathic arthritis. 2009:43P.
4.	AGREE Next Steps Consortium. The AGREE Ⅲ Instrument, 2011. Available at:http://www.agreetrust.org.
5.	Burls A. AGREE Ⅲ-improving the quality of clinical care. Lancet, 2010, 376(9747):1128-1129.
6.	Zadvinskis IM, Grudell BA. Clinical practice guideline appraisal using the AGREE instrument:renal screening. Clin Nurse Spec, 2010, 24(4):209-214.
7.	Field MJ, Lohr KN. Guidelines for clinical practice:from development to use. Washington:National Academy Press, 1992.
8.	張伶俐, 李幼平, 張川, 等. 中國兒童臨床指南現狀分析及循證臨床指南評價. 中國循證醫學雜志, 2011, 11(9):991-999.
9.	楊克虎, 陳耀龍, 李幼平, 等. 中國能否應對指南挑戰? 中國循證醫學雜志, 2013, 13(6):621-623.
10.	李永柏. 幼年特發性關節炎(多/少關節型)診療建議解讀. 2011年全國兒科風濕性疾病診治專題研討會論文匯編, 2011:55-62.
11.	屠志強, 蔡宇波, 曹蘭芳. 2011年美國風濕病學會關于幼年特發性關節炎的治療建議. 實用兒科臨床雜志, 2011, 26(21):1689-1692.
12.	Vincenzi B, Napolitano A, Santini D, et al. Evidence-based guidelines:improving AGREEment on consistence evaluation. Journal of Bone Oncology, 2012, 1(1):30-34.
13.	韋當, 王小琴, 吳瓊芳, 等. 2011年中國臨床實踐指南質量評價. 中國循證醫學雜志, 2013, 13(6):760-763.

1. 安云飛, 趙曉東. 幼年特發性關節炎發病機制及進展. 中國醫藥指南, 2008, 6(12):46-48.
2. 《中華兒科雜志》編輯委員會, 中華醫學會兒科學分會免疫學組. 幼年特發性關節炎(多/少關節型)診療建議. 中華兒科雜志,2012, 50(1):20-26.
3. National Health and Medical Research Council. Clinical guideline for the diagnosis and management of juvenile idiopathic arthritis. 2009:43P.
4. AGREE Next Steps Consortium. The AGREE Ⅲ Instrument, 2011. Available at:http://www.agreetrust.org.
5. Burls A. AGREE Ⅲ-improving the quality of clinical care. Lancet, 2010, 376(9747):1128-1129.
6. Zadvinskis IM, Grudell BA. Clinical practice guideline appraisal using the AGREE instrument:renal screening. Clin Nurse Spec, 2010, 24(4):209-214.
7. Field MJ, Lohr KN. Guidelines for clinical practice:from development to use. Washington:National Academy Press, 1992.
8. 張伶俐, 李幼平, 張川, 等. 中國兒童臨床指南現狀分析及循證臨床指南評價. 中國循證醫學雜志, 2011, 11(9):991-999.
9. 楊克虎, 陳耀龍, 李幼平, 等. 中國能否應對指南挑戰? 中國循證醫學雜志, 2013, 13(6):621-623.
10. 李永柏. 幼年特發性關節炎(多/少關節型)診療建議解讀. 2011年全國兒科風濕性疾病診治專題研討會論文匯編, 2011:55-62.
11. 屠志強, 蔡宇波, 曹蘭芳. 2011年美國風濕病學會關于幼年特發性關節炎的治療建議. 實用兒科臨床雜志, 2011, 26(21):1689-1692.
12. Vincenzi B, Napolitano A, Santini D, et al. Evidence-based guidelines:improving AGREEment on consistence evaluation. Journal of Bone Oncology, 2012, 1(1):30-34.
13. 韋當, 王小琴, 吳瓊芳, 等. 2011年中國臨床實踐指南質量評價. 中國循證醫學雜志, 2013, 13(6):760-763.

Chinese Journal of Evidence-Based Medicine

Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review

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