Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study_Chinese Journal of Evidence-Based Medicine

Authors：

 TANWen-fei , SHIYue ,  FANGBo , MAHong

Department of Anesthesiology, the First Hospital of China Medical University, Shenyang 110001, China;

Corresponding?author：

FANGBo, Email: drunk0630@126.com

Keywords：

Thyroidectomy; Postoperative headache; Flurbiprofen axetil; Case-control study

DOI：

10.7507/1672-2531.20150084

Video：

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Objective To investigate the risk factors of perioperative anaesthesia management in postoperative headache induced by thyroidectomy. Methods A 1:1 age and operation time matched case-control design study was performed. General anesthesia patients for elective thyroidectomy with postoperative headache (case group, VAS score >4) and without postoperative headache (control group, VAS score ≤4) were recruited. Univariate and multivariate analyses were performed to analyze the risk factors of postoperative headache after 24 and 48 hours of operation by using SPSS 18.0 software. Results A total of 134 patients were included; of which, 67 were in the case group and the other 67 were in the control group. The results of univariate analysis showed that female and administration of flurbiprofen axetil might be the risk factors of postoperative headache. The further multivariate analysis showed that administration of flurbiprofen axetil was significantly associated with decreased postoperative headache (OR=0.387, 95%CI 0.185 to 0.811). Conclusion Perioperative anesthesia management has a certain influence on postoperative headache induced by thyroidectomy. The use of flurbiprofen axetil during operation could reduce the incidence rate of postoperative headache.

Citation： TANWen-fei, SHIYue, FANGBo, MAHong. Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study. Chinese Journal of Evidence-Based Medicine, 2015, 15(5): 500-502. doi: 10.7507/1672-2531.20150084 Copy

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2.	王敬美, 孫翠梅, 蘇娟. 甲狀腺手術后頭枕部疼痛的預防與護理. 中國實用護理雜志, 2006, 22(32):27-28.
3.	卜淑娟, 黃夏蕾, 方文. 甲狀腺手術前頭低肩高體位練習時間的研究. 護士進修雜志, 2005, 20(7):593-594.
4.	莊春柳, 黃步英, 陳燕珠, 等. 適時體位干預及改進體位墊在甲狀腺手術病人中的應用探討. 護理研究, 2005, 19(8):692-693.
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10.	Han DW, Koo BN, Chung WY, et al. Preoperative greater occipital nerve block in total thyroidectomy patients can reduce postoperative occipital headache and posterior neck pain. Thyroid, 2006, 16(6):599-603.
11.	陳競文, 宋陸軍. 甲狀腺癌的流行病學新特點. 中國臨床醫學, 2009, 16(5):812-813.
12.	賀純靜, 聶浩雄, 郭春芮, 等. 氟比洛芬酯術后鎮痛對老年髖關節置換術患者術后認知功能的影響. 臨床麻醉學雜志, 2013, 29(1):13-15.
13.	馬艷輝, 吳潔, 張瑛, 等. 氟比洛芬酯復合舒芬太尼用于下肢骨科術后靜脈鎮痛的效果. 上海醫學, 2013, 36(2):158-160.
14.	陳紅, 王玉, 曹文超, 等. 氟比洛芬酯術后鎮痛對神經外科患者內皮素水平的影響. 臨床麻醉學雜志, 2013, 29(1):60-61.
15.	Su C, Su Y, Chou CW, et al. Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis. J Cardiothorac Surg, 2012, 7(21):98.
16.	Yamashita K, Fukusaki M, Ando Y, et al. Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. J Anesth, 2006, 20(2):92-95.
17.	蔣新, 李莉. 體位干預減輕甲狀腺手術患者不適效果觀察. 蚌埠醫學院學報, 2009, 34(7):638-639.
18.	李莉, 黃麗華, 劉美平, 等. 術前體位訓練預防甲狀腺手術體位綜合征的臨床觀察. 中國實用護理雜志, 2007, 23(2):27-28.
19.	徐翔, 李義賢. 氟比洛芬酯預防頭頸外科手術術后疼痛的應用研究. 中國實用醫藥, 2014, 9(12):126-127.

1. 陳曦, 李宏為. 當今甲狀腺外科手術的特點. 外科理論與實踐, 2012, (1):1-3.
2. 王敬美, 孫翠梅, 蘇娟. 甲狀腺手術后頭枕部疼痛的預防與護理. 中國實用護理雜志, 2006, 22(32):27-28.
3. 卜淑娟, 黃夏蕾, 方文. 甲狀腺手術前頭低肩高體位練習時間的研究. 護士進修雜志, 2005, 20(7):593-594.
4. 莊春柳, 黃步英, 陳燕珠, 等. 適時體位干預及改進體位墊在甲狀腺手術病人中的應用探討. 護理研究, 2005, 19(8):692-693.
5. 林建玲, 鄧潔娜, 青毅, 等. 舒適體位在全麻甲狀腺手術的臨床觀察. 中國醫藥導報, 2012, 9(15):184-185.
6. 孫淑琴, 楊瑞華, 呂哲. 甲狀腺手術術前頸仰臥位練習的臨床意義. 黑龍江醫學, 2001, 25(8):609.
7. 范鷹, 閆朝岐, 張一娜. 甲狀腺手術體位對患者術后頭痛和嘔吐癥狀及精神心理狀態的影響. 中國臨床康復, 2005, 9(20):66-67.
8. 陳濤. 甲狀腺術后頭痛的原因淺析. 中國臨床醫學, 2005, 12(3):460.
9. 楊成林, 王小強. 甲狀腺術后頭痛及預防. 現代腫瘤醫學, 2007, 15(6):851-852.
10. Han DW, Koo BN, Chung WY, et al. Preoperative greater occipital nerve block in total thyroidectomy patients can reduce postoperative occipital headache and posterior neck pain. Thyroid, 2006, 16(6):599-603.
11. 陳競文, 宋陸軍. 甲狀腺癌的流行病學新特點. 中國臨床醫學, 2009, 16(5):812-813.
12. 賀純靜, 聶浩雄, 郭春芮, 等. 氟比洛芬酯術后鎮痛對老年髖關節置換術患者術后認知功能的影響. 臨床麻醉學雜志, 2013, 29(1):13-15.
13. 馬艷輝, 吳潔, 張瑛, 等. 氟比洛芬酯復合舒芬太尼用于下肢骨科術后靜脈鎮痛的效果. 上海醫學, 2013, 36(2):158-160.
14. 陳紅, 王玉, 曹文超, 等. 氟比洛芬酯術后鎮痛對神經外科患者內皮素水平的影響. 臨床麻醉學雜志, 2013, 29(1):60-61.
15. Su C, Su Y, Chou CW, et al. Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis. J Cardiothorac Surg, 2012, 7(21):98.
16. Yamashita K, Fukusaki M, Ando Y, et al. Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. J Anesth, 2006, 20(2):92-95.
17. 蔣新, 李莉. 體位干預減輕甲狀腺手術患者不適效果觀察. 蚌埠醫學院學報, 2009, 34(7):638-639.
18. 李莉, 黃麗華, 劉美平, 等. 術前體位訓練預防甲狀腺手術體位綜合征的臨床觀察. 中國實用護理雜志, 2007, 23(2):27-28.
19. 徐翔, 李義賢. 氟比洛芬酯預防頭頸外科手術術后疼痛的應用研究. 中國實用醫藥, 2014, 9(12):126-127.

Chinese Journal of Evidence-Based Medicine

Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study

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