Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial_Chinese Journal of Evidence-Based Medicine

Authors：

 HEWan-qiang , LUOWei-hua , LILei , JIANGLiang

Department of Burns and Plastic Surgery, Dazhou Central Hospital, Dazhou 635000, China;

Corresponding?author：

Keywords：

Diabetic foot; ulcer; Silver ions dressing; Randomized controlled trial

DOI：

10.7507/1672-2531.20160079

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Objective To investigate the clinical therapeutic effect of silver ions dressing for patient with diabetic foot ulcers. Methods According to the diagnostic and classification criteria of diabetes and diabetic foot of World Health Organization (WHO), outpatients and inpatients with diabetic foot ulcers admitted to the Department of Burns and Plastic Surgery of Dazhou Central Hospital from October 2013 to May 2015 were randomly divided into a silver ion dressing treatment group and a traditional dressing treatment group. The effective rate, time of occurrence of granulation tissue, wound healing time and wound area reduction ratio between the two groups were compared by using SPSS17.0 software. Results A total of 80 patients were included, of which 40 patients in each group. Compared with the control group, the total effective rate was higher (92.5% vs. 62.5%, P=0.001), the occurrence time of granulation tissue (6.4±0.72 vs. 10.8 ±1.9, P=0.000) and wound healing time (31.3±8.2 vs. 47.4±11.5, P=0.000) were shorter, and the wound area reduction ration was greater (46.3±7.6 vs. 32.6±6.1, P=0.000) in the silver ions dressing group with significant differences. Conclusion The effects of silver-containing dressings is superior to Vaseline dressing in the treatment of diabetic foot ulcers.

Citation： HEWan-qiang, LUOWei-hua, LILei, JIANGLiang. Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial. Chinese Journal of Evidence-Based Medicine, 2016, 16(5): 510-512. doi: 10.7507/1672-2531.20160079 Copy

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4.	U?kay I, Aragón-Sánchez J, Lew D, et al. Diabetic Foot Infections: What have we learned in the last 30 years? Int J Infect Dis, 2015, 40: 81-91.
5.	劉仁海, 高霞. 含銀離子敷料治療2-3級糖尿病足潰瘍42例. 中國藥業, 2012, 21(9): 50-51.
6.	唐蕾, 陳亞文, 趙千雋. 銀離子抗菌敷料應用于糖尿病足患者的臨床觀察. 上海護理, 2009, 9(6): 50-51.
7.	宋瑞捧, 沈珂珂, 馬豪莉, 等. 表皮生長因子聯合銀離子敷料治療糖尿病足感染的臨床研究. 中華醫院感染學雜志, 2014, 24(16): 4033-4035.
8.	諶靜, 陳盛業. 新換藥方法治療糖尿病足的臨床觀察. 疾病監測與控制, 2014, 24(16): 792-793.
9.	邱吉苗, 謝翠華, 李春榮. 含銀離子敷料治療糖尿病足潰瘍50例. 廣東醫學2007, 28(3): 472.
10.	郭春蘭, 鄧紅艷. 含銀敷料輔助治療糖尿病足潰瘍感染的效果觀察. 華西醫學 2014, 29(9): 1611-1614.
11.	周艷斌, 陳友華. 銀離子敷料治療糖尿病足傷口效果觀察. 護理學雜志, 2015, 25(15): 86.
12.	陳志雄. 銀離子敷料聯合水凝膠治療糖尿病足的效果觀察. 現代醫院, 2015,15(3): 82-83.
13.	向英, 張恒術, 鄒靜, 等. 創新敷料治療糖尿病足潰瘍的臨床研究. 中國藥房, 2012, 23(22): 2063-2064.
14.	李旭亞, 丁惠萍. 糖尿病足感染傷口治療中使用銀離子敷料的臨床觀察. 護理實踐與研究, 2009, 6(20): 34-35.
15.	何書連, 李曉燕. 濕性敷料在糖尿病足換藥護理中的應用. 現代預防醫學, 2012, 39(15): 4020-4021.

1. Noor S, Zubair M, Ahmad J. Diabetic foot ulcer——A review on pathophysiology, classification and microbial etiology. Diabetes Metab Syndr, 2015, 9(3): 192-199.
2. Charles PG, U?kay I, Kressmann B, et al. The role of anaerobes in diabetic foot infections. Anaerobe, 2015, 34: 8-13.
3. 李梅, 周瓏, 張鶴. 銀離子敷料在普外科換藥中的應用研究及進展. 臨床普外科電子雜志, 2014, 2(1): 45-47.
4. U?kay I, Aragón-Sánchez J, Lew D, et al. Diabetic Foot Infections: What have we learned in the last 30 years? Int J Infect Dis, 2015, 40: 81-91.
5. 劉仁海, 高霞. 含銀離子敷料治療2-3級糖尿病足潰瘍42例. 中國藥業, 2012, 21(9): 50-51.
6. 唐蕾, 陳亞文, 趙千雋. 銀離子抗菌敷料應用于糖尿病足患者的臨床觀察. 上海護理, 2009, 9(6): 50-51.
7. 宋瑞捧, 沈珂珂, 馬豪莉, 等. 表皮生長因子聯合銀離子敷料治療糖尿病足感染的臨床研究. 中華醫院感染學雜志, 2014, 24(16): 4033-4035.
8. 諶靜, 陳盛業. 新換藥方法治療糖尿病足的臨床觀察. 疾病監測與控制, 2014, 24(16): 792-793.
9. 邱吉苗, 謝翠華, 李春榮. 含銀離子敷料治療糖尿病足潰瘍50例. 廣東醫學2007, 28(3): 472.
10. 郭春蘭, 鄧紅艷. 含銀敷料輔助治療糖尿病足潰瘍感染的效果觀察. 華西醫學 2014, 29(9): 1611-1614.
11. 周艷斌, 陳友華. 銀離子敷料治療糖尿病足傷口效果觀察. 護理學雜志, 2015, 25(15): 86.
12. 陳志雄. 銀離子敷料聯合水凝膠治療糖尿病足的效果觀察. 現代醫院, 2015,15(3): 82-83.
13. 向英, 張恒術, 鄒靜, 等. 創新敷料治療糖尿病足潰瘍的臨床研究. 中國藥房, 2012, 23(22): 2063-2064.
14. 李旭亞, 丁惠萍. 糖尿病足感染傷口治療中使用銀離子敷料的臨床觀察. 護理實踐與研究, 2009, 6(20): 34-35.
15. 何書連, 李曉燕. 濕性敷料在糖尿病足換藥護理中的應用. 現代預防醫學, 2012, 39(15): 4020-4021.

Chinese Journal of Evidence-Based Medicine

Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial

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