Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey_Chinese Journal of Evidence-Based Medicine

Authors：

 HUZhi-qiang ^1,2,3,4 ,  ZHANGLing-li ^1,2,3 ,  LIYou-ping ⁵ , WANChao-min ⁶ , QUANShu-yan ^1,2,3,4 , ZENGLi-nan ^1,2,3 , JIANGLu-can ^1,2,3,4 , GUIGe ^1,2,3,4

1. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
2. Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
3. Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China;
4. West China School of Pharmacy, Sichuan University, Chengdu 610041, China;
5. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;
6. Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China;

Corresponding?author：

ZHANGLing-li, Email: zhlingli@sina.com; LIYou-ping, Email: yzmylab@hotmail.com

Keywords：

Medical institution; Children; Essential medicine; Dosage form; Specifications; Demand; Cross-sectional survey

DOI：

10.7507/1672-2531.20160096

Video：

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Objective To investigate and compare the demands of dosage forms and specifications of essential medicine for children in different levels of medical institutions, so as to provide references for selection of essential medicines for children by levels of medical institutions. Methods In 13 provinces or municipalities, 104 medical institutions, including tertiary, secondary and primacy medical institutions, were investigated by questionnaires. Kinds of drugs, dosage forms, requirement types and requirement levels of drugs were analyzed and compared in different levels of medical institutions. Results Tertiary medical institutions had higher demands than other levels of medical institutions for the number of drugs types, dosage forms and level of demand on each drug (P < 0.05), secondary medical institutions were higher than primacy medical institutions (P < 0.05), but community health service centers were the same as township health centers. Conclusion The demands of dosage forms and specifications of essential medicine for children in different levels of medical institutions are different. So future studies should develop the essential medicines list for children depend on different levels of care.

Citation： HUZhi-qiang, ZHANGLing-li, LIYou-ping, WANChao-min, QUANShu-yan, ZENGLi-nan, JIANGLu-can, GUIGe. Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey. Chinese Journal of Evidence-Based Medicine, 2016, 16(6): 621-627. doi: 10.7507/1672-2531.20160096 Copy

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3.	WHO. WHO Policy Perspectives on Medicines - The Selection of Essential Medicines. 2002.
4.	王莉, 周幫曼, 宋佳佳, 等. 25國基本藥物目錄循證評價. 中國循證醫學雜志, 2009, 9(7): 754-764.
5.	車明鳳, 韓白石. 我國頒布實施國家基本藥物目錄的概況. 中國藥事, 2000, 14(1): 19-21.
6.	陳晶, 聶青, 劉妍. 《WHO基本藥物示范目錄》與我國《國家基本藥物目錄》動態調整程序比較與借鑒. 中國藥房, 2015(3): 289-293.
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8.	劉丹, 程靜, 張伶俐, 等. WHO、印度、南非兒童基本藥物目錄與中國2012版基本藥物目錄的比較研究. 中國循證醫學雜志, 2015, (4): 393-402.
9.	李友佳, 楊世民. 《國家基本藥物目錄》兒童用藥分析及思考. 中國藥事, 2014, 28(4): 349-353.
10.	錢麗萍, 馬亞娜, 張瑩. 我國兒童基本藥物政策框架設計. 中國藥房, 2014, 25(12): 1060-1062.
11.	李幼平, 沈建通. 基本藥物目錄遴選與使用的發展與創新. 中國循證醫學雜志, 2013, 13(11): 1273-1279.
12.	Walid Bin Hosain. 孟加拉國及其他國家基本藥物政策對中國的啟示. 復旦大學, 2009.
13.	徐文娟. 我國基本藥物目錄及其實施現況. 復旦大學, 2012.
14.	全淑燕, 張伶俐, 李幼平等. 我國兒童急需但缺乏的基本藥物劑型和規格的遴選. 中國循證醫學雜志, 2016, 16(5): 497-504.
15.	米術斌, 張雷, 段一娜, 等. SPSS軟件進行隨機區組設計非參數檢驗的多重比較. 現代預防醫學, 2009, 36(2): 217-219.
16.	李曉松. 醫學統計學. 北京：高等教育出版社, 2008.
17.	郭春彥, 王曉玲. 我國兒童藥物劑型和規格的現狀. 兒科藥學雜志, 2013, 19(8): 53-55.
18.	張伶俐, 李幼平, 胡蝶, 等. 我國兒童藥物短缺的現狀分析. 中國循證醫學雜志, 2012, 12(10): 1159-1164.
19.	國家衛生和計劃生育委員會. 關于保障兒童用藥的若干意見. Available at: http://www.mohrss.gov.cn/SYrlzyhshbzb/ldbk/shehuibaozhang/yiliao/201406/t20140605_131493.htm.
20.	Medicines and Healthcare Products Regulatory Agency (MHRA).Department of health strategy on medicines for children. 2004.

1. ?World Health Assembly. Resolution WHA 28.66. Geneva: World Health Organization, 1975.
2. WHO. WHO Model Lists of Essential Medicines. Available at: http://www.who.int/medicines/publications/essentialmedicines/en/.
3. WHO. WHO Policy Perspectives on Medicines - The Selection of Essential Medicines. 2002.
4. 王莉, 周幫曼, 宋佳佳, 等. 25國基本藥物目錄循證評價. 中國循證醫學雜志, 2009, 9(7): 754-764.
5. 車明鳳, 韓白石. 我國頒布實施國家基本藥物目錄的概況. 中國藥事, 2000, 14(1): 19-21.
6. 陳晶, 聶青, 劉妍. 《WHO基本藥物示范目錄》與我國《國家基本藥物目錄》動態調整程序比較與借鑒. 中國藥房, 2015(3): 289-293.
7. 藥物政策與基本藥物制度司. 2012年版《國家基本藥物目錄》發布. Available at: http://www.moh.gov.cn/mohywzc/s3582/201303/b058a4edf14e4dc9a1f6f0f0c71a2cce.shtml.
8. 劉丹, 程靜, 張伶俐, 等. WHO、印度、南非兒童基本藥物目錄與中國2012版基本藥物目錄的比較研究. 中國循證醫學雜志, 2015, (4): 393-402.
9. 李友佳, 楊世民. 《國家基本藥物目錄》兒童用藥分析及思考. 中國藥事, 2014, 28(4): 349-353.
10. 錢麗萍, 馬亞娜, 張瑩. 我國兒童基本藥物政策框架設計. 中國藥房, 2014, 25(12): 1060-1062.
11. 李幼平, 沈建通. 基本藥物目錄遴選與使用的發展與創新. 中國循證醫學雜志, 2013, 13(11): 1273-1279.
12. Walid Bin Hosain. 孟加拉國及其他國家基本藥物政策對中國的啟示. 復旦大學, 2009.
13. 徐文娟. 我國基本藥物目錄及其實施現況. 復旦大學, 2012.
14. 全淑燕, 張伶俐, 李幼平等. 我國兒童急需但缺乏的基本藥物劑型和規格的遴選. 中國循證醫學雜志, 2016, 16(5): 497-504.
15. 米術斌, 張雷, 段一娜, 等. SPSS軟件進行隨機區組設計非參數檢驗的多重比較. 現代預防醫學, 2009, 36(2): 217-219.
16. 李曉松. 醫學統計學. 北京：高等教育出版社, 2008.
17. 郭春彥, 王曉玲. 我國兒童藥物劑型和規格的現狀. 兒科藥學雜志, 2013, 19(8): 53-55.
18. 張伶俐, 李幼平, 胡蝶, 等. 我國兒童藥物短缺的現狀分析. 中國循證醫學雜志, 2012, 12(10): 1159-1164.
19. 國家衛生和計劃生育委員會. 關于保障兒童用藥的若干意見. Available at: http://www.mohrss.gov.cn/SYrlzyhshbzb/ldbk/shehuibaozhang/yiliao/201406/t20140605_131493.htm.
20. Medicines and Healthcare Products Regulatory Agency (MHRA).Department of health strategy on medicines for children. 2004.

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Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey

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