Implant survival and aesthetic outcomes between immediate <i>versus</i> delayed implant treatment in the anterior maxilla regions: a meta-analysis _Chinese Journal of Evidence-Based Medicine

Authors：

ZHANG Jian ¹ ,  SUN Xiaofeng ¹ , ZHANG Ping ²

1. Department of Stomatology, Wuxi No.2 Hospital, Nanjing Medical University, Wuxi, 214102, P.R.China;
2. School of Biotechnoleogy, JiangNan University, Wuxi, 214122, P.R.China;

Corresponding?author：

SUN Xiaofeng, Email: zorain@126.com

Keywords：

Immediate implant; Delayed implant; Anterior teeth area; Retention rate; Pink esthetic score; Meta-analysis; Randomized controlled trial; Cohort study

DOI：

10.7507/1672-2531.201706003

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

ObjectiveTo systematically review the implant survival and postoperative aesthetics of immediate versus delayed implant treatment in the anterior maxilla regions.MethodsWe searched databases including PubMed, The Cochrane Library, EMbase, CBM, CNKI and WanFang Data from inception to April 2017, to collect randomized controlled trials (RCTs) and cohort studies on immediate implant and delayed implant in the anterior teeth areas. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, RevMan 5.3 software was used to perform meta-analysis.ResultsA total of 4 RCTs and 12 retrospective cohort studies involving 1 316 implants were finally included. The results of meta-analysis showed that: there was no significant difference between two groups in retention rate (RCT: RR=0.99, 95%CI 0.97 to 1.02, P=0.70; retrospective cohort study: RR=0.99, 95%CI 0.96 to 1.02, P=0.54), the implant stability of permanent restoration for 4 months (MD=0.82, 95%CI –0.11 to 1.76, P=0.08), alveolar bone resorption of long-term permanent crown restoration (12 months: RCT: MD=0.06, 95%CI –0.35 to 0.47, P=0.79; retrospective cohort study: MD=–0.27, 95%CI –0.57 to 0.03, P=0.07; 24 months: retrospective cohort study MD=–0.09, 95%CI –0.18 to 0.00, P=0.05), respectively. The immediate implant group was superior to the control group in alveolar bone resorption of short-term permanent crown restoration (3 months: MD=–0.08, 95%CI –0.13 to –0.04, P=0.000 1; 6 months: MD=–0.23, 95%CI –0.38 to –0.07, P=0.004). The PES score in the immediate implant group was higher than that in the delayed implant group(MD=1.12, 95%CI 0.11 to 2.13, P=0.03).ConclusionsCurrent evidence shows that both immediate and delayed implant procedures have similar outcomes in terms of implant retention, long-term stability and long-term alveolar bone resorption of the implants in the anterior maxilla regions, but the former procedure possesses better short-term reduction of alveolar bone absorption and postoperative gingival aesthetics. Furthermore, due to the limited quality and quantity of the included studies, more large-scale and high-quality studies are needed to verify the above conclusions.

Citation： ZHANG Jian, SUN Xiaofeng, ZHANG Ping. Implant survival and aesthetic outcomes between immediate versus delayed implant treatment in the anterior maxilla regions: a meta-analysis . Chinese Journal of Evidence-Based Medicine, 2018, 18(3): 342-350. doi: 10.7507/1672-2531.201706003 Copy

1.	林野. 即刻種植的是與非. 中華口腔醫學雜志, 2013, 48(4): 193-198.
2.	Rosenquist B, Grenthe B. Immediate placement of implants into extraction sockets: implant survival. Int J Oral Maxillofac Implants, 1996, 11(2): 205-209.
3.	Cornelini R, Scarano A, Covani U, et al. Immediate one-stage postextration implant: a human clinical and hisologic case report. Int J Oral Maxillofac Implants, 2000, 15(3):432-437.
4.	Bartee BK. Extration site reconstrucation for alveolar ridge preservation. J Oral Implantology, 2001, 27(4): 187-191.
5.	Mayer TM, Hawley CE, Gunsolley JC, et al. The single- tooth implant: a viable alternative for single-tooth replacement. J Periodontol, 2002, 73(7):687-693.
6.	Available at: http//ohri.ca/programs/clinical_epidemilolgy/ oxford.asp.
7.	Schropp L, Kostopoulos L, Wenzel A, et al. Clinical and radiographic performance of delayed-immediate single-tooth implant placement associated with peri-implant bone defects. a 2-year prospective, controlled, randomized follow-up report. J Clin Periodontol, 2005, 32(4): 480-487.
8.	Crespi R, Cappare P, Gherlone E, et al. Immediate versus delayed loading of dental implants placed in fresh extraction sockets in the maxillary esthetic zone: a clinical comparative study. Int J Oral Maxillofac Implants, 2008, 23(4): 753-758.
9.	Esposito M, Barausse C, Pistilli R, et al. Immediate loading of post-extractive versus delayed placed single implants in the anterior maxilla: outcome of a pragmatic multicenter randomised controlled trial 1-year after loading. Eur J Oral Implantol, 2015, 8(4): 347-358.
10.	Felice P, Zucchelli G, Cannizzaro G, et al. Immediate-delayed (6 weeks) and delayed (4 months) post-extractive single implants: 4-month post-loading data from a randomised controlled trial. Eur J Oral Implantol, 2016, 9(3): 233-247.
11.	Malchiodi L, Balzani L, Cucchi A. Primary and secondary stability of implants in postextraction and healed sites: a randomized controlled clinical trial. Int J Oral Maxillofac Implants, 2016, 31(6): 1435-1443.
12.	郭觀生, 李一新, 李志鵬, 等. 前牙區微創即刻種植即刻修復與常規種植修復美學效果臨床研究. 中國醫學創新, 2016, 13(20): 129-141.
13.	浦益萍. 前牙即刻種植修復臨床療效的研究. 上海: 上海交通大學, 2008.
14.	吳敏節, 張相皞, 鄒立東, 等. 前牙即刻種植和常規種植修復2年后軟、硬組織穩定性比較,北京大學學報(醫學版), 2015, 47(1): 67-71.
15.	徐景明, 陳冬雷, 王培, 等. 前牙微創拔牙后即刻種植和位點保存常規種植療效的臨床回顧性研究. 口腔醫學, 2017, 37(4): 325-330.
16.	謝霓, 朱友家. 即刻種植與延期種植在單顆前牙修復的臨床效果比較. 臨床口腔醫學雜志, 2015, 31(12): 758-759.
17.	田瑞雪, 唐旭炎, 徐錦程. 即刻種植和延期種植修復前牙的臨床效果研究. 中國現代醫學雜志, 2017, 27(4): 121-125.
18.	胡衛子, 何家才, 汪向東. 上前牙區即刻種植修復臨床牙齦美學觀察. 安徽醫學, 2011, 32(9): 1248-1250.
19.	李偉, 張志宏, 邊華琴, 等. 即刻與延期前牙種植義齒修復的臨床效果及主觀滿意度調查. 重慶醫學, 2015, 44(8): 1103-1105.
20.	姚希, 張寧, 李昀生, 等. 前牙的即刻與延期種植: 牙周組織健康程度及成功率比較. 中國組織工程研究, 2015, 19(12): 1958-1963.
21.	陳勇, 楊保全. 78例即刻種植術和延期種植術遠期療效追蹤報告. 臨床口腔醫學雜志, 2007, 23(4): 220-221.
22.	周宏志, 賀平, 趙軍, 等. 不同骨缺損條件下的即刻與延期種植修復的臨床應用評價. 口腔醫學研究, 2008, 24(6): 685-687.
23.	Sun Z, Herring SW, Tee BC, et al. Alveolar ridge reduction after tooth extraction in adolescents: an animal study. Arch Oral Biol, 2013, 58(7): 813-825.
24.	Park MS, Park YB, Choi H, et al. Morphometric analysis of maxillary alveolar regions for immediate implantation. J Adv Prosthodont, 2013, 5(4): 494-501.
25.	Li B, Wang Y. Contour changes in human alveolar bone following tooth extraction of the maxillary central incisor. J Zhejiang Univ Sci B, 2014, 15(12): 1064-1071.
26.	Schulte W, Kleineikenscheidt H, Schareyka R, et al. Concept and testing of the Tübingen immediate implant. Dtsch Zahnarztl Z, 1978, 33(5): 319-325.
27.	Hürzeler MB, Fickl S, Zuhr O, et al. Clinical failures and shortfalls of immediate implant procedures. Eur J Esthet Dent, 2006, 1(2): 128-140.
28.	Chen ST, Darby IB, Reynolds EC. A prospective clinical study of non-submerged immediate implants: clinical outcomes and esthetic results. Clin Oral Implants Res, 2007, 18(5): 552-562.
29.	Evans CD, Chen ST. Esthetic outcomes of immediate implant placements. Clin Oral Implants Res, 2008, 19(1): 73-80.
30.	H?mmerle CH, Araujo MG, Simion M. Evidence-based knowledge on the biology and treatment of extraction sockets. Osteology Consensus Gmup 2011. Clin Oral Implants Res, 2012, 23 Suppl 5: 80-82.
31.	Kan JY, Rungcharassaeng K, Morimoto T, et al. Facial gingival tissue stability after connective tissue graft with single immediate tooth replacement in the esthetic zone: consecutive case report. J Oral Maxillofac, 2009, 67(11 Suppl): 40-48.
32.	Block MS, Mercante DE, Lirette D, et al. Prospective evaluation of immediate and delayed pmvisional single tooth restoralions. J Oral Maxillofac Surg, 2009, 67(11 Suppl): 89-107.
33.	Raes F, Cosyn J, Crommelinck E, et al. Immediate and conventional single implant treatment in the anterior maxilla: 1-year results of a case series on hard and soft tissue response and aesthetics. J Clin Periodontol, 2011, 38(4): 385-394.
34.	Sammartino G, Marenzi G, di Lauro AE, et al. Aesthetics in oral implantology: biological, clinical, surgical, and prosthetic aspects. Implant Dentistry, 2007, 16(1): 54-65.

1. 林野. 即刻種植的是與非. 中華口腔醫學雜志, 2013, 48(4): 193-198.
2. Rosenquist B, Grenthe B. Immediate placement of implants into extraction sockets: implant survival. Int J Oral Maxillofac Implants, 1996, 11(2): 205-209.
3. Cornelini R, Scarano A, Covani U, et al. Immediate one-stage postextration implant: a human clinical and hisologic case report. Int J Oral Maxillofac Implants, 2000, 15(3):432-437.
4. Bartee BK. Extration site reconstrucation for alveolar ridge preservation. J Oral Implantology, 2001, 27(4): 187-191.
5. Mayer TM, Hawley CE, Gunsolley JC, et al. The single- tooth implant: a viable alternative for single-tooth replacement. J Periodontol, 2002, 73(7):687-693.
6. Available at: http//ohri.ca/programs/clinical_epidemilolgy/ oxford.asp.
7. Schropp L, Kostopoulos L, Wenzel A, et al. Clinical and radiographic performance of delayed-immediate single-tooth implant placement associated with peri-implant bone defects. a 2-year prospective, controlled, randomized follow-up report. J Clin Periodontol, 2005, 32(4): 480-487.
8. Crespi R, Cappare P, Gherlone E, et al. Immediate versus delayed loading of dental implants placed in fresh extraction sockets in the maxillary esthetic zone: a clinical comparative study. Int J Oral Maxillofac Implants, 2008, 23(4): 753-758.
9. Esposito M, Barausse C, Pistilli R, et al. Immediate loading of post-extractive versus delayed placed single implants in the anterior maxilla: outcome of a pragmatic multicenter randomised controlled trial 1-year after loading. Eur J Oral Implantol, 2015, 8(4): 347-358.
10. Felice P, Zucchelli G, Cannizzaro G, et al. Immediate-delayed (6 weeks) and delayed (4 months) post-extractive single implants: 4-month post-loading data from a randomised controlled trial. Eur J Oral Implantol, 2016, 9(3): 233-247.
11. Malchiodi L, Balzani L, Cucchi A. Primary and secondary stability of implants in postextraction and healed sites: a randomized controlled clinical trial. Int J Oral Maxillofac Implants, 2016, 31(6): 1435-1443.
12. 郭觀生, 李一新, 李志鵬, 等. 前牙區微創即刻種植即刻修復與常規種植修復美學效果臨床研究. 中國醫學創新, 2016, 13(20): 129-141.
13. 浦益萍. 前牙即刻種植修復臨床療效的研究. 上海: 上海交通大學, 2008.
14. 吳敏節, 張相皞, 鄒立東, 等. 前牙即刻種植和常規種植修復2年后軟、硬組織穩定性比較,北京大學學報(醫學版), 2015, 47(1): 67-71.
15. 徐景明, 陳冬雷, 王培, 等. 前牙微創拔牙后即刻種植和位點保存常規種植療效的臨床回顧性研究. 口腔醫學, 2017, 37(4): 325-330.
16. 謝霓, 朱友家. 即刻種植與延期種植在單顆前牙修復的臨床效果比較. 臨床口腔醫學雜志, 2015, 31(12): 758-759.
17. 田瑞雪, 唐旭炎, 徐錦程. 即刻種植和延期種植修復前牙的臨床效果研究. 中國現代醫學雜志, 2017, 27(4): 121-125.
18. 胡衛子, 何家才, 汪向東. 上前牙區即刻種植修復臨床牙齦美學觀察. 安徽醫學, 2011, 32(9): 1248-1250.
19. 李偉, 張志宏, 邊華琴, 等. 即刻與延期前牙種植義齒修復的臨床效果及主觀滿意度調查. 重慶醫學, 2015, 44(8): 1103-1105.
20. 姚希, 張寧, 李昀生, 等. 前牙的即刻與延期種植: 牙周組織健康程度及成功率比較. 中國組織工程研究, 2015, 19(12): 1958-1963.
21. 陳勇, 楊保全. 78例即刻種植術和延期種植術遠期療效追蹤報告. 臨床口腔醫學雜志, 2007, 23(4): 220-221.
22. 周宏志, 賀平, 趙軍, 等. 不同骨缺損條件下的即刻與延期種植修復的臨床應用評價. 口腔醫學研究, 2008, 24(6): 685-687.
23. Sun Z, Herring SW, Tee BC, et al. Alveolar ridge reduction after tooth extraction in adolescents: an animal study. Arch Oral Biol, 2013, 58(7): 813-825.
24. Park MS, Park YB, Choi H, et al. Morphometric analysis of maxillary alveolar regions for immediate implantation. J Adv Prosthodont, 2013, 5(4): 494-501.
25. Li B, Wang Y. Contour changes in human alveolar bone following tooth extraction of the maxillary central incisor. J Zhejiang Univ Sci B, 2014, 15(12): 1064-1071.
26. Schulte W, Kleineikenscheidt H, Schareyka R, et al. Concept and testing of the Tübingen immediate implant. Dtsch Zahnarztl Z, 1978, 33(5): 319-325.
27. Hürzeler MB, Fickl S, Zuhr O, et al. Clinical failures and shortfalls of immediate implant procedures. Eur J Esthet Dent, 2006, 1(2): 128-140.
28. Chen ST, Darby IB, Reynolds EC. A prospective clinical study of non-submerged immediate implants: clinical outcomes and esthetic results. Clin Oral Implants Res, 2007, 18(5): 552-562.
29. Evans CD, Chen ST. Esthetic outcomes of immediate implant placements. Clin Oral Implants Res, 2008, 19(1): 73-80.
30. H?mmerle CH, Araujo MG, Simion M. Evidence-based knowledge on the biology and treatment of extraction sockets. Osteology Consensus Gmup 2011. Clin Oral Implants Res, 2012, 23 Suppl 5: 80-82.
31. Kan JY, Rungcharassaeng K, Morimoto T, et al. Facial gingival tissue stability after connective tissue graft with single immediate tooth replacement in the esthetic zone: consecutive case report. J Oral Maxillofac, 2009, 67(11 Suppl): 40-48.
32. Block MS, Mercante DE, Lirette D, et al. Prospective evaluation of immediate and delayed pmvisional single tooth restoralions. J Oral Maxillofac Surg, 2009, 67(11 Suppl): 89-107.
33. Raes F, Cosyn J, Crommelinck E, et al. Immediate and conventional single implant treatment in the anterior maxilla: 1-year results of a case series on hard and soft tissue response and aesthetics. J Clin Periodontol, 2011, 38(4): 385-394.
34. Sammartino G, Marenzi G, di Lauro AE, et al. Aesthetics in oral implantology: biological, clinical, surgical, and prosthetic aspects. Implant Dentistry, 2007, 16(1): 54-65.

Chinese Journal of Evidence-Based Medicine

Implant survival and aesthetic outcomes between immediate versus delayed implant treatment in the anterior maxilla regions: a meta-analysis

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content