Prevalence of senile pruritus in Chinese population: a meta-analysis_Chinese Journal of Evidence-Based Medicine

Authors：

CHEN Shi ,  GAO Jing , BAI Dingxi , HE Lianci , ZHONG Yizhu , BAO Xinru , WU Qiao , WU Chenxi

School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P.R.China;

Corresponding?author：

GAO Jing, Email: 729012934@qq.com

Keywords：

China; Senile pruritus; Epidemiological characteristics; Prevalence; Meta-analysis; Systematic review; Cross-sectional study

DOI：

10.7507/1672-2531.201910023

Video：

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Objectives To systematically review the prevalence of senile pruritus (SP) in Chinese population.Methods PubMed, EMbase, CENTRAL, CINAHL, CBM, CNKI, WanFang Data and VIP databases were electronically searched to collect cross-sectional studies on the prevalence of SP in Chinese population from inception to May 2019. Two reviewers independently screened literature, extracted data and assessed risk of bias of included studies, then, meta-analysis was performed by Stata 12.0 software.Results A total of 11 studies involving 13 398 patients were included. The results of meta-analysis showed that, the overall prevalence of SP was 31.0% (95%CI 18.0% to 44.0%). Subgroup analysis showed that the prevalence rate of male was 34.9% (95%CI 18.6% to 88.5%). The prevalence rates of SP among 60, 70, 80 and 90 age groups were 20.0% (95%CI 14.2% to 25.7%), 48.4% (95%CI 21.5% to 75.3%), 53% (95%CI 12.4% to 93.5%), and 58.5% (95%CI 22.4% to 94.6%), respectively. The prevalence rates of SP in community, hospital and cadre relaxation club were 33.4% (95%CI 31.3% to 35.6%), 40.4% (95%CI 22% to 58.7%), and 14.4% (95%CI 1.1% to 27.7%), respectively. The prevalence rates of SP in southern China and northern China were 26.7% (95%CI 18.7% to 34.7%) and 36.8% (95%CI 21.8% to 51.7%), respectively.Conclusions The overall prevalence rate of SP in the Chinese population is high. The prevalence rates of SP among ages, regions and research sites are different.

Citation： CHEN Shi, GAO Jing, BAI Dingxi, HE Lianci, ZHONG Yizhu, BAO Xinru, WU Qiao, WU Chenxi. Prevalence of senile pruritus in Chinese population: a meta-analysis. Chinese Journal of Evidence-Based Medicine, 2020, 20(5): 562-567. doi: 10.7507/1672-2531.201910023 Copy

1.	張倩, 王洪志, 高靜, 等. 中醫調欲療法對老年性皮膚瘙癢癥患者睡眠質量的影響. 中華護理雜志, 2017, 52(2): 161-165.
2.	張倩, 高靜, 史蘭輝, 等. 中醫情志調欲法對老年皮膚瘙癢癥患者癥狀及生活質量的影響. 中國老年學雜志, 2016, 36(19): 4897-4899.
3.	曾憲濤, 劉慧, 陳曦, 等. Meta分析系列之四: 觀察性研究的質量評價工具. 中國循證心血管醫學雜志, 2012, 4(4): 297-299.
4.	熊風, 賴玉清, 涂嘉欣, 等. 中國老年人群睡眠障礙流行特征的Meta分析. 中國循證醫學雜志, 2019, 19(4): 28-33.
5.	張麗. 太原市中老年干部皮膚病調查. 太原: 山西醫科大學, 2012.
6.	陳祖輝, 莫海霞, 冼俊芳, 等. 廣州某社區老年人皮膚病現狀及其影響因素. 暨南大學學報(自然科學與醫學版), 2015, 36(1): 73-76.
7.	葛蒙梁, 謝志宏, 張春玲, 等. 122例單純性老年瘙癢癥相關因素的病例對照研究. 中華流行病學雜志, 2006, 27(7): 627-629.
8.	侯秀芳, 張力軍. 老年皮膚病196例影響因素調查分析. 陜西醫學雜志, 2016, 45(11): 1559-1560.
9.	李丹, 竇娜, 馬素慧, 等. 老年皮膚瘙癢癥的危險因素分析. 中國全科醫學, 2013, 16(26): 3062-3065.
10.	李琳, 王婷, 劉曉崢. 老年性皮膚瘙癢癥的危險因素分析及健康指導. 西南軍醫, 2014, (5): 591-592.
11.	倪鶴梁, 柯曉燕, 錢明強, 等. 上海市兩家養老機構老年瘙癢性皮膚病發病情況分析. 中國中西醫結合皮膚性病學雜志, 2012, 11(3): 25-26.
12.	武娜, 張東玲. 老年性皮膚瘙癢癥的調查及病因分析. 中國療養醫學, 2014, 23(4): 90-91.
13.	薛樹旗. 太鋼職工老年性皮膚病調查. 中國皮膚性病學雜志, 2008, 22(7): 32-33.
14.	楊潔, 趙華, 周勇, 等. 410名男性老年瘙瘁癥患者危險因素病例對照研究. 現代預防醫學, 2009, 36(10): 1820-1822.
15.	Tseng HW, Ger LP, Liang CK, et al. High prevalence of cutaneous manifestations in the elderly with diabetes mellitus: an institution-based cross-sectional study in Taiwan. J Eur Acad Dermatol Venereol, 2015, 29(8): 1631-1635.
16.	Thaipisuttikul Y. Pruritic skin diseases in the elderly. J Dermatol, 1998, 25(3): 153-157.
17.	Caretti KL, Mehregan DR, Mehregan DA. A survey of self-reported skin disease in the elderly African-American population. Int J Dermatol, 2015, 54(9): 1034-1038.
18.	Valdes-Rodriguez R, Mollanazar NK, González-Muro J, et al. Itch prevalence and characteristics in a Hispanic geriatric population: a comprehensive study using a standardized itch questionnaire. Acta Derm Venereol, 2015, 95(4): 417-421.
19.	Reszke R, Bia?ynicki-Birula R, Lindner K, et al. Itch in elderly people: a cross-sectional study. Acta Derm Venereol, 2019, 99(11): 1016-1021.
20.	唐樺. AQP3在不同年齡段正常人皮膚組織及角質形成細胞, 成纖維細胞中的表達. 長沙: 中南大學, 2008.
21.	張子衿, 祝均, 孟宏, 等. 老年性瘙癢癥發病機制研究進展. 中國老年學雜志, 2018, 38(18): 251-253.
22.	Fang D, Elly C, Gao B, et al. Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation. Nat Immunol, 2002, 3(3): 281-287.
23.	Bretscher PA. On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases. Scand J Immunol, 2014, 79(6): 361-376.
24.	李元文, 李楠. 皮膚瘙癢癥中醫診治專家共識(北京地區). 北京中醫藥, 2017, (9): 777-779.
25.	Reszke R, Pe?ka D, Walasek A, et al. Skin disorders in elderly subjects. Int J Dermatol, 2015, 54(9): e332-e338.

1. 張倩, 王洪志, 高靜, 等. 中醫調欲療法對老年性皮膚瘙癢癥患者睡眠質量的影響. 中華護理雜志, 2017, 52(2): 161-165.
2. 張倩, 高靜, 史蘭輝, 等. 中醫情志調欲法對老年皮膚瘙癢癥患者癥狀及生活質量的影響. 中國老年學雜志, 2016, 36(19): 4897-4899.
3. 曾憲濤, 劉慧, 陳曦, 等. Meta分析系列之四: 觀察性研究的質量評價工具. 中國循證心血管醫學雜志, 2012, 4(4): 297-299.
4. 熊風, 賴玉清, 涂嘉欣, 等. 中國老年人群睡眠障礙流行特征的Meta分析. 中國循證醫學雜志, 2019, 19(4): 28-33.
5. 張麗. 太原市中老年干部皮膚病調查. 太原: 山西醫科大學, 2012.
6. 陳祖輝, 莫海霞, 冼俊芳, 等. 廣州某社區老年人皮膚病現狀及其影響因素. 暨南大學學報(自然科學與醫學版), 2015, 36(1): 73-76.
7. 葛蒙梁, 謝志宏, 張春玲, 等. 122例單純性老年瘙癢癥相關因素的病例對照研究. 中華流行病學雜志, 2006, 27(7): 627-629.
8. 侯秀芳, 張力軍. 老年皮膚病196例影響因素調查分析. 陜西醫學雜志, 2016, 45(11): 1559-1560.
9. 李丹, 竇娜, 馬素慧, 等. 老年皮膚瘙癢癥的危險因素分析. 中國全科醫學, 2013, 16(26): 3062-3065.
10. 李琳, 王婷, 劉曉崢. 老年性皮膚瘙癢癥的危險因素分析及健康指導. 西南軍醫, 2014, (5): 591-592.
11. 倪鶴梁, 柯曉燕, 錢明強, 等. 上海市兩家養老機構老年瘙癢性皮膚病發病情況分析. 中國中西醫結合皮膚性病學雜志, 2012, 11(3): 25-26.
12. 武娜, 張東玲. 老年性皮膚瘙癢癥的調查及病因分析. 中國療養醫學, 2014, 23(4): 90-91.
13. 薛樹旗. 太鋼職工老年性皮膚病調查. 中國皮膚性病學雜志, 2008, 22(7): 32-33.
14. 楊潔, 趙華, 周勇, 等. 410名男性老年瘙瘁癥患者危險因素病例對照研究. 現代預防醫學, 2009, 36(10): 1820-1822.
15. Tseng HW, Ger LP, Liang CK, et al. High prevalence of cutaneous manifestations in the elderly with diabetes mellitus: an institution-based cross-sectional study in Taiwan. J Eur Acad Dermatol Venereol, 2015, 29(8): 1631-1635.
16. Thaipisuttikul Y. Pruritic skin diseases in the elderly. J Dermatol, 1998, 25(3): 153-157.
17. Caretti KL, Mehregan DR, Mehregan DA. A survey of self-reported skin disease in the elderly African-American population. Int J Dermatol, 2015, 54(9): 1034-1038.
18. Valdes-Rodriguez R, Mollanazar NK, González-Muro J, et al. Itch prevalence and characteristics in a Hispanic geriatric population: a comprehensive study using a standardized itch questionnaire. Acta Derm Venereol, 2015, 95(4): 417-421.
19. Reszke R, Bia?ynicki-Birula R, Lindner K, et al. Itch in elderly people: a cross-sectional study. Acta Derm Venereol, 2019, 99(11): 1016-1021.
20. 唐樺. AQP3在不同年齡段正常人皮膚組織及角質形成細胞, 成纖維細胞中的表達. 長沙: 中南大學, 2008.
21. 張子衿, 祝均, 孟宏, 等. 老年性瘙癢癥發病機制研究進展. 中國老年學雜志, 2018, 38(18): 251-253.
22. Fang D, Elly C, Gao B, et al. Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation. Nat Immunol, 2002, 3(3): 281-287.
23. Bretscher PA. On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases. Scand J Immunol, 2014, 79(6): 361-376.
24. 李元文, 李楠. 皮膚瘙癢癥中醫診治專家共識(北京地區). 北京中醫藥, 2017, (9): 777-779.
25. Reszke R, Pe?ka D, Walasek A, et al. Skin disorders in elderly subjects. Int J Dermatol, 2015, 54(9): e332-e338.

Chinese Journal of Evidence-Based Medicine

Prevalence of senile pruritus in Chinese population: a meta-analysis

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