Methodological recommendations in the topic selection and question formulation of integrated traditional Chinese and Western medicine clinical practice guideline_Chinese Journal of Evidence-Based Medicine

Authors：

WANG Jianxin ^1,2 , GAO Xuemin ³ , LI Rui ^4,5 , SHI Qi ^1,3 , DAI Xinyue ^1,2 ,  GAO Rui ^1,2

1. Xiyuan Hospital Affiliated to China Academy of Chinese Medical Sciences, Beijing 100091, P. R. China;
2. National Medical Products Administration for Laboratory for Clinical Research and Evaluation of Traditional Chinese Medicine, Beijing 100091, P. R. China;
3. Beijing University of Chinese Medicine, Beijing 100105, P. R. China;
4. The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 50000, P. R. China;
5. Henan Evidence Based Chinese Medicine Center, Zhengzhou 450000, P. R. China;

Corresponding?author：

GAO Rui, Email: ruigao@126.com

Keywords：

Integrated traditional Chinese and Western medicine; Evidence-based clinical practice guideline; Guide theme; Clinical problem

DOI：

10.7507/1672-2531.202501003

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Construct clinical questions is the basis in developing the evidence-based clinical practice guidelines. The identification of the topics and clinical questions in the evidence-based clinical practice guidelines of integrated traditional Chinese and Western medicine is the most challenging procedure in the process of developing guidelines, but there is still a lack of systematic formulation process and methodological recommendations. This article takes the construction of the topics and clinical questions of the "Clinical Application Guidelines for the Prevention and Treatment of Acute Pharyngitis with Integrated Traditional Chinese and Western Medicine" as an example, expounds the process and methodological suggestions for the construction of the topics and clinical questions, so as to provide a reference for the formulation and improve the quality and clinical applicability of the evidence-based clinical practice guidelines of integrated traditional Chinese and Western medicine.

Citation： WANG Jianxin, GAO Xuemin, LI Rui, SHI Qi, DAI Xinyue, GAO Rui. Methodological recommendations in the topic selection and question formulation of integrated traditional Chinese and Western medicine clinical practice guideline. Chinese Journal of Evidence-Based Medicine, 2025, 25(10): 1191-1196. doi: 10.7507/1672-2531.202501003 Copy

1.	中西醫聯合防治策略標準研究項目組. 《中西醫聯合防治優勢病種臨床應用指南》制訂技術規范. 中國中西醫結合雜志, 2024, 44(4): 389-398.
2.	靳英輝, 韓斐, 王強, 等. 臨床實踐指南制訂方法—指南范圍、主題及問題的確定. 中國循證心血管醫學雜志, 2018, 10(3): 257-261.
3.	Jin YH, Wang YP, Xie YL, et al. Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine. Mil Med Res, 2023, 10(1): 45.
4.	陳薇, 劉建平. 中西醫結合臨床實踐指南制訂原則和流程. 中國中西醫結合雜志, 2022, 42(12): 1413-1417.
5.	白英哲, 王燁燃, 黃璐琦. 中醫疾病名稱的特征、存在問題與研究思路. 中醫雜志, 2024, 65(7): 661-668.
6.	趙國楨, 宗星煜, 趙學堯, 等. 中醫證候分類標準形成的關鍵技術及方法學思考. 中國實驗方劑學雜志, 2024, 30(24): 257-261.
7.	中華醫學會, 中華醫學會雜志社, 中華醫學會全科醫學分會, 等. 急性上呼吸道感染基層診療指南(2018年). 中華全科醫師雜志, 2019, 18(5): 422-426.
8.	《中成藥治療優勢病種臨床應用指南》標準化項目組. 中成藥治療小兒急性上呼吸道感染臨床應用指南(2020年). 中國中西醫結合雜志, 2021, 41(2): 143-150.
9.	姚曉燕, 邊永君, 高揚, 等. 《中醫藥單用/聯合抗生素治療急性咽炎疾病臨床實踐指南》臨床應用評價與修訂意見. 中國中藥雜志, 2018, 43(24): 4765-4770.
10.	Huang Y, Wu T, Zeng L, et al. Chinese medicinal herbs for sore throat. Cochrane Database Syst Rev, 2012, (3): CD004877.
11.	李澤鵬, 李文建, 孫志佳. 中成藥治療急性咽炎數據挖掘及網狀Meta分析. 山東大學耳鼻喉眼學報, 2023, 37(4): 111-118.
12.	Aertgeerts B, Agoritsas T, Siemieniuk RAC, et al. Corticosteroids for sore throat: a clinical practice guideline. BMJ, 2017, 358: j4090.
13.	van Driel ML, De Sutter AI, Thorning S, et al. Different antibiotic treatments for group A streptococcal pharyngitis. Cochrane Database Syst Rev, 2021, (3): CD004406.
14.	Ebell MH, Barry HC. Management of sore throat: time to update. Am Fam Physician, 2024, 109(4): 301-302.
15.	Krüger K, T?pfner N, Berner R, et al. Clinical practice guideline: sore throat. Dtsch Arztebl Int, 2021, 118(11): 188-194.
16.	張霞, 謝雁鳴, 李光熙, 等. 中醫藥治療急性咽炎的優勢與問題探討. 中國中藥雜志, 2017, 42(19): 3819-3825.
17.	田晨, 劉雅菲, 盧婷婷, 等. 中西醫結合快速推薦指南技術與方法. 中國中西醫結合雜志, 2025, 45(4): 389-396.
18.	張莉莉, 薛崇祥, 周凌, 等. 由靶及態之現代中西醫結合醫學模式探析. 中醫雜志, 2023, 64(22): 2269-2274.
19.	謝伊, 林洪生, 張英. 基于醫學發展史探索中西醫結合方法與途徑. 中國中西醫結合雜志, 2023, 43(11): 1375-1379.
20.	彭蓉晏, 孫凌云, 劉稼璽, 等. 基于改良德爾菲法構建《早中期結直腸癌根治術后中西醫結合心理康復干預指南》臨床問題. 中國中西醫結合雜志, 2024, 44(8): 912-920.
21.	靳英輝, 閻思宇, 任相穎, 等. 《中西醫融合臨床實踐指南制訂規范》解讀. 醫學新知, 2024, 34(12): 1319-1328.
22.	高一城, 劉芷含, 夏如玉, 等. 中醫藥臨床實踐指南臨床問題構建中干預措施的優先性選擇—基于專家證據的方法學建議. 中國循證醫學雜志, 2023, 23(4): 433-438.
23.	王雅琪, 高一城, 蘇澄元, 等. 臨床實踐指南中臨床問題結構化分級及評價. 中國循證醫學雜志, 2024, 24(7): 827-831.
24.	Pelucchi C, Grigoryan L, et al. Guideline for the management of acute sore throat. Clin Microbiol Infect, 2012, 18(Suppl 1): 1-28.
25.	National Institute for Health and Care Excellence. Sore throat (acute): antimicrobial prescribing. 2018.
26.	陳思語, 郭孟楊, 鄧江紅, 等. A族鏈球菌咽炎的臨床診斷及評分制的應用進展. 中國當代兒科雜志, 2024, 26(8): 893-898.
27.	陳耀龍, 羅旭飛, 史乾靈, 等. 人工智能如何改變指南的未來. 協和醫學雜志, 2021, 12(1): 114-121.
28.	Sousa-Pinto B, Marques-Cruz M, Neumann I, et al. Guidelines international network: principles for use of artificial intelligence in the health guideline enterprise. Ann Intern Med, 2025, 178(3): 408-415.
29.	Sousa-Pinto B, Vieira RJ, Marques-Cruz M, et al. Artificial intelligence-supported development of health guideline questions. Ann Intern Med, 2024, 177(11): 1518-1529.

1. 中西醫聯合防治策略標準研究項目組. 《中西醫聯合防治優勢病種臨床應用指南》制訂技術規范. 中國中西醫結合雜志, 2024, 44(4): 389-398.
2. 靳英輝, 韓斐, 王強, 等. 臨床實踐指南制訂方法—指南范圍、主題及問題的確定. 中國循證心血管醫學雜志, 2018, 10(3): 257-261.
3. Jin YH, Wang YP, Xie YL, et al. Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine. Mil Med Res, 2023, 10(1): 45.
4. 陳薇, 劉建平. 中西醫結合臨床實踐指南制訂原則和流程. 中國中西醫結合雜志, 2022, 42(12): 1413-1417.
5. 白英哲, 王燁燃, 黃璐琦. 中醫疾病名稱的特征、存在問題與研究思路. 中醫雜志, 2024, 65(7): 661-668.
6. 趙國楨, 宗星煜, 趙學堯, 等. 中醫證候分類標準形成的關鍵技術及方法學思考. 中國實驗方劑學雜志, 2024, 30(24): 257-261.
7. 中華醫學會, 中華醫學會雜志社, 中華醫學會全科醫學分會, 等. 急性上呼吸道感染基層診療指南(2018年). 中華全科醫師雜志, 2019, 18(5): 422-426.
8. 《中成藥治療優勢病種臨床應用指南》標準化項目組. 中成藥治療小兒急性上呼吸道感染臨床應用指南(2020年). 中國中西醫結合雜志, 2021, 41(2): 143-150.
9. 姚曉燕, 邊永君, 高揚, 等. 《中醫藥單用/聯合抗生素治療急性咽炎疾病臨床實踐指南》臨床應用評價與修訂意見. 中國中藥雜志, 2018, 43(24): 4765-4770.
10. Huang Y, Wu T, Zeng L, et al. Chinese medicinal herbs for sore throat. Cochrane Database Syst Rev, 2012, (3): CD004877.
11. 李澤鵬, 李文建, 孫志佳. 中成藥治療急性咽炎數據挖掘及網狀Meta分析. 山東大學耳鼻喉眼學報, 2023, 37(4): 111-118.
12. Aertgeerts B, Agoritsas T, Siemieniuk RAC, et al. Corticosteroids for sore throat: a clinical practice guideline. BMJ, 2017, 358: j4090.
13. van Driel ML, De Sutter AI, Thorning S, et al. Different antibiotic treatments for group A streptococcal pharyngitis. Cochrane Database Syst Rev, 2021, (3): CD004406.
14. Ebell MH, Barry HC. Management of sore throat: time to update. Am Fam Physician, 2024, 109(4): 301-302.
15. Krüger K, T?pfner N, Berner R, et al. Clinical practice guideline: sore throat. Dtsch Arztebl Int, 2021, 118(11): 188-194.
16. 張霞, 謝雁鳴, 李光熙, 等. 中醫藥治療急性咽炎的優勢與問題探討. 中國中藥雜志, 2017, 42(19): 3819-3825.
17. 田晨, 劉雅菲, 盧婷婷, 等. 中西醫結合快速推薦指南技術與方法. 中國中西醫結合雜志, 2025, 45(4): 389-396.
18. 張莉莉, 薛崇祥, 周凌, 等. 由靶及態之現代中西醫結合醫學模式探析. 中醫雜志, 2023, 64(22): 2269-2274.
19. 謝伊, 林洪生, 張英. 基于醫學發展史探索中西醫結合方法與途徑. 中國中西醫結合雜志, 2023, 43(11): 1375-1379.
20. 彭蓉晏, 孫凌云, 劉稼璽, 等. 基于改良德爾菲法構建《早中期結直腸癌根治術后中西醫結合心理康復干預指南》臨床問題. 中國中西醫結合雜志, 2024, 44(8): 912-920.
21. 靳英輝, 閻思宇, 任相穎, 等. 《中西醫融合臨床實踐指南制訂規范》解讀. 醫學新知, 2024, 34(12): 1319-1328.
22. 高一城, 劉芷含, 夏如玉, 等. 中醫藥臨床實踐指南臨床問題構建中干預措施的優先性選擇—基于專家證據的方法學建議. 中國循證醫學雜志, 2023, 23(4): 433-438.
23. 王雅琪, 高一城, 蘇澄元, 等. 臨床實踐指南中臨床問題結構化分級及評價. 中國循證醫學雜志, 2024, 24(7): 827-831.
24. Pelucchi C, Grigoryan L, et al. Guideline for the management of acute sore throat. Clin Microbiol Infect, 2012, 18(Suppl 1): 1-28.
25. National Institute for Health and Care Excellence. Sore throat (acute): antimicrobial prescribing. 2018.
26. 陳思語, 郭孟楊, 鄧江紅, 等. A族鏈球菌咽炎的臨床診斷及評分制的應用進展. 中國當代兒科雜志, 2024, 26(8): 893-898.
27. 陳耀龍, 羅旭飛, 史乾靈, 等. 人工智能如何改變指南的未來. 協和醫學雜志, 2021, 12(1): 114-121.
28. Sousa-Pinto B, Marques-Cruz M, Neumann I, et al. Guidelines international network: principles for use of artificial intelligence in the health guideline enterprise. Ann Intern Med, 2025, 178(3): 408-415.
29. Sousa-Pinto B, Vieira RJ, Marques-Cruz M, et al. Artificial intelligence-supported development of health guideline questions. Ann Intern Med, 2024, 177(11): 1518-1529.

Chinese Journal of Evidence-Based Medicine

Methodological recommendations in the topic selection and question formulation of integrated traditional Chinese and Western medicine clinical practice guideline

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content