迷走神經刺激術治療癲癇標準操作流程（草案）_Journal of Epilepsy

Authors：

 中國抗癲癇協會

執筆吳欣桐（四川大學華西醫院）；趙晨陽（四川大學華西醫院）；周東（四川大學華西醫院）;

Corresponding?author：

中國抗癲癇協會, Email: 36853839@qq.com

Keywords：

DOI：

10.7507/2096-0247.202502003

Video：

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Citation： 中國抗癲癇協會. 迷走神經刺激術治療癲癇標準操作流程（草案）. Journal of Epilepsy, 2025, 11(2): 96-99, 120. doi: 10.7507/2096-0247.202502003 Copy

1.	Ding D, Zhou D, Sander JW, et al. Epilepsy in China: major progress in the past two decades. The Lancet Neurology, 2021, 20(4): 316-326.
2.	Keezer MR, Sisodiya SM, Sander JW. Comorbidities of epilepsy: current concepts and future perspectives. The Lancet Neurology, 2016, 15(1): 106-115.
3.	Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia, 2010, 51(6): 1069-1077.
4.	中國抗癲癇協會神經調控專業委員會, 中國醫師協會神經調控專業委員會, 中華醫學會神經外科分會神經生理學組. 迷走神經刺激治療藥物難治性癲癇的中國專家共識. 癲癇雜志, 2021, 7(3): 191-196.
5.	Fukuda M, Matsuo T, Fujimoto S, et al. Vagus nerve stimulation therapy for drug-resistant epilepsy in children-a literature review. Journal of Clinical Medicine, 2024, 13(3): 245-251.
6.	Toffa DH, Touma L, El Meskine T, et al. Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review. Seizure, 2020, 83: 104-123.
7.	中國醫師協會神經內科分會癲專委會. 迷走神經刺激術治療癲(癎)的中國專家共識. 中國醫師雜志, 2015, 17(7): 967-968.
8.	中華醫學會編著. 臨床診療指南. 癲癇病分冊(2023修訂版). 北京: 人民衛生出版社, 2023.
9.	Morris GL, Gloss D, Buchhalter J, et al. Evidence-based guideline update: vagus nerve stimulation for the treatment of epilepsy. 2013, 81(16): 1453-1459.
10.	Spuck S, Tronnier V, Orosz I, et al. Operative and technical complications of vagus nerve stimulator implantation. Neurosurgery, 2010, 67(2 Suppl Operative): 489-494.
11.	Ardesch JJ, Sikken JR, Veltink PH, et al. Vagus nerve stimulation for epilepsy activates the vocal folds maximally at therapeutic levels. Epilepsy Research, 2010, 89(2-3): 227-231.
12.	Hsieh T, Chen M, McAfee A, et al. Sleep-related breathing disorder in children with vagal nerve stimulators. Pediatric Neurology, 2008, 38(2): 99-103.
13.	Zaaimi B, Grebe R, Berquin P, et al. Vagus nerve stimulation induces changes in respiratory sinus arrhythmia of epileptic children during sleep. Epilepsia, 2009, 50(11): 2473-2480.
14.	Malow BA, Edwards J, Marzec M, et al. Effects of vagus nerve stimulation on respiration during sleep: a pilot study. Neurology, 2000, 55(10): 1450-1454.

1. Ding D, Zhou D, Sander JW, et al. Epilepsy in China: major progress in the past two decades. The Lancet Neurology, 2021, 20(4): 316-326.
2. Keezer MR, Sisodiya SM, Sander JW. Comorbidities of epilepsy: current concepts and future perspectives. The Lancet Neurology, 2016, 15(1): 106-115.
3. Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia, 2010, 51(6): 1069-1077.
4. 中國抗癲癇協會神經調控專業委員會, 中國醫師協會神經調控專業委員會, 中華醫學會神經外科分會神經生理學組. 迷走神經刺激治療藥物難治性癲癇的中國專家共識. 癲癇雜志, 2021, 7(3): 191-196.
5. Fukuda M, Matsuo T, Fujimoto S, et al. Vagus nerve stimulation therapy for drug-resistant epilepsy in children-a literature review. Journal of Clinical Medicine, 2024, 13(3): 245-251.
6. Toffa DH, Touma L, El Meskine T, et al. Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review. Seizure, 2020, 83: 104-123.
7. 中國醫師協會神經內科分會癲專委會. 迷走神經刺激術治療癲(癎)的中國專家共識. 中國醫師雜志, 2015, 17(7): 967-968.
8. 中華醫學會編著. 臨床診療指南. 癲癇病分冊(2023修訂版). 北京: 人民衛生出版社, 2023.
9. Morris GL, Gloss D, Buchhalter J, et al. Evidence-based guideline update: vagus nerve stimulation for the treatment of epilepsy. 2013, 81(16): 1453-1459.
10. Spuck S, Tronnier V, Orosz I, et al. Operative and technical complications of vagus nerve stimulator implantation. Neurosurgery, 2010, 67(2 Suppl Operative): 489-494.
11. Ardesch JJ, Sikken JR, Veltink PH, et al. Vagus nerve stimulation for epilepsy activates the vocal folds maximally at therapeutic levels. Epilepsy Research, 2010, 89(2-3): 227-231.
12. Hsieh T, Chen M, McAfee A, et al. Sleep-related breathing disorder in children with vagal nerve stimulators. Pediatric Neurology, 2008, 38(2): 99-103.
13. Zaaimi B, Grebe R, Berquin P, et al. Vagus nerve stimulation induces changes in respiratory sinus arrhythmia of epileptic children during sleep. Epilepsia, 2009, 50(11): 2473-2480.
14. Malow BA, Edwards J, Marzec M, et al. Effects of vagus nerve stimulation on respiration during sleep: a pilot study. Neurology, 2000, 55(10): 1450-1454.

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迷走神經刺激術治療癲癇標準操作流程（草案）

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