基于2017版癲癇發作分類框架，國際抗癲癇聯盟（International League Against Epilepsy，ILAE）完成了癲癇發作操作性分類標準的更新。本次修訂由ILAE執行委員會任命的37人工作組共同完成：通過改良Delphi法（共識閾值設定為超過三分之二的多數）公開征求意見后形成修訂方案。該修訂方案在ILAE 官網公示征求意見后，執委會任命7名專家組成修訂小組對反饋意見進行整合，最終更新的分類標準于2025年4月在Epilepsia上發表。更新后的分類標準延續四大主要發作類別：局灶性、全面性、未知是否為局灶性或全面性和無法分類的發作，共包含4個主要類別和21種具體發作類型，并特別注重非英語語種的術語可譯性，旨在為從資源有限地區到高級專科癲癇中心的所有癲癇從業人員建立統一術語體系，并為患者及照護者提供通俗易懂的表述。鑒于癲癇發作分類在癲癇診斷和治療中的重要作用，本文融合中國癲癇領域專家解讀《癲癇發作分類標準更新：國際抗癲癇聯盟立場聲明》并形成共識，旨在推進該分類標準在我國癲癇領域臨床和科研中的應用。
Citation：
高慧, 樂治軍, 安東梅, 陳佳妮, 陳蕾, 姜維嘉, 李偉, 朱遂強, 汪昕, 周列民, 姜玉武, 張建國, 鄧艷春, 丁美萍, 趙國光, 林衛紅, 張國君, 丁玎, 王群, 陳陽美, 任連坤, 王小姍, 欒國明, 秦炯, 廖衛平, 王學峰, 肖波, 王玉平, 王藝, 劉曉燕, 周東. 《癲癇發作分類標準更新：國際抗癲癇聯盟立場聲明》中國專家解讀. Journal of Epilepsy, 2025, 11(4): 310-317. doi: 10.7507/2096-0247.202505003
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Gastaut H. Clinical and electroencephalographical classification of epileptic seizures. Epilepsia, 1970, 11(1): 102-113.
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Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia, 1981, 22(4): 489-501.
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Berg A T, Millichap J J. The 2010 revised classification of seizures and epilepsy. Continuum (Minneapolis, Minn. ), 2013, 19(3 Epilepsy): 571-597.
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Fisher R S, Cross J H, French J A, et al. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia, 2017, 58(4): 522-530.
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中華醫學會神經病學分會, 中華醫學會神經病學分會腦電圖與癲癇學組. 國際抗癲癇聯盟癇性發作新分類中國專家解讀. 中華神經科雜志, 2019, 52(11): 977-980.
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| 6. |
Berg A T, Berkovic S F, Brodie M J, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(4): 676-685.
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- 1. Gastaut H. Clinical and electroencephalographical classification of epileptic seizures. Epilepsia, 1970, 11(1): 102-113.
- 2. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia, 1981, 22(4): 489-501.
- 3. Berg A T, Millichap J J. The 2010 revised classification of seizures and epilepsy. Continuum (Minneapolis, Minn. ), 2013, 19(3 Epilepsy): 571-597.
- 4. Fisher R S, Cross J H, French J A, et al. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia, 2017, 58(4): 522-530.
- 5. 中華醫學會神經病學分會, 中華醫學會神經病學分會腦電圖與癲癇學組. 國際抗癲癇聯盟癇性發作新分類中國專家解讀. 中華神經科雜志, 2019, 52(11): 977-980.
- 6. Berg A T, Berkovic S F, Brodie M J, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(4): 676-685.
