【摘要】 目的 探討研究靜脈滴注丹參注射液發生不良反應的類型及因素，為臨床用藥提供依據。 方法 對2007年1月-2010年12月82例因靜脈滴注丹參注射液發生不良反應的患者資料進行回顧分析，并對其相關因素進行分析。 結果 男性的不良發生率高于女性，不良反應發生年齡多為中、老年患者，并且不良反應多發生在輸液30 min內，多為Ⅰ型過敏反應。 結論 對丹參注射液應嚴格控制生產工藝流程，臨床用藥要掌握適應證，以避免不良反應的發生。
【Abstract】 Objective To investigate the types and factors of adverse reactions caused by intravenous infusion of Danshen injection, in order to provide basis for clinical drug application. Methods We retrospectively analyzed the clinical records of 82 patients with adverse reaction to intravenous infusion of Danshen injection from January 2007 to December 2010. Results Adverse reaction incidence was higher in males than females, and it mainly occurred in patients of middle or old ages. Most of the adverse reactions happened within 30 minutes of the infusion. Type-I allergic reaction was more commonly observed. Conclusion In order to avoid the occurrence of adverse reactions, Danshen injection production process should be strictly controlled, and indications should be considered carefully in clinical medication.
Citation： GAN Xiaohong,LIU Lei,ZENG Xiangping. Analysis of Adverse Drug Reaction Induced by Intravenous Infusion of Danshen Injection. West China Medical Journal, 2011, 26(12): 1856-1858. doi: Copy
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