【摘要】 目的 比較喉罩-七氟醚、雷米芬太尼與喉罩-丙泊酚、雷米芬太尼兩種麻醉方法在小兒短小手術應用中的優缺點。 方法 2009年3-9月，將40例擇期行斜疝手術或隱睪下降固定術的患兒，隨機分為A、B組，各20例。A組施喉罩+七氟醚+雷米芬太尼，B組施喉罩+丙泊酚+雷米芬太尼。觀察誘導時間、術中生命體征、蘇醒時間、麻醉后恢復室（PACU）停留時間、圍術期并發癥。 結果 麻醉前兩組患兒血壓及心率無統計學差異，麻醉后B組各時點血壓及心率明顯低于麻醉前水平，且B組各時點血壓及心率明顯低于A組，A組血壓及心率在麻醉前后比較無統計學差異。B組麻醉誘導時間明顯短于A組。A組術后躁動發生率明顯高于B組。 結論 與喉罩+丙泊酚+雷米芬太尼相比，喉罩+七氟醚+雷米芬太尼具有對全身影響小、麻醉平穩等特點，但麻醉誘導時間長，術后躁動發生率高。
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戴貴茂,李秀澤,李衛. 喉罩-超短效麻醉藥在小兒短小手術中的應用. 華西醫學, 2010, 25(12): 2260-2262. doi:
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- 1. 李師陽, 姚偉瑜, 肖全勝, 等. 患兒吸入七氟醚麻醉誘導的效果[J]. 中華麻醉學雜志, 2007, 27(2): 186.
- 2. 鄭洪, 譚朝華. 喉罩下吸入麻醉加骶麻在小兒尿道下裂成形術中的應用[J]. 臨床小兒外科雜志, 2007, 6(1): 38-39.
- 3. Oczenski W, Krenn H, Dahaba AA, et al. Hemodynamic and catecholamine stress responses to insertion of the Combitube, laryngeal mask airway or tracheal intubation[J]. Anesth Analg, 1999, 88(6): 1389-1394.
- 4. Ross AK, Davis PJ, Deal GDEL, et al. Pharmacokinetics of remifentanil in anesthetized pediatric patient s undergoing elective surgery or diagnostic procedures[J]. Anesth Analg, 2001, 93(6): 1393-1401.
- 5. Spahr-Schopfer IA, Bissonnette B, Hartley EJ. Capnometry and the pediatric laryngeal mask airway[J]. Can J Anaesth, 1993, 40(4): 1038-1043.
- 6. Murat I, Billard V, Vernois J, et al. Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches[J]. Anesthesiology, 1996, 84(3): 526-532.
- 7. Martlew RA, Meakin G, Wadsworth R, et al. Dose of propofol for laryngeal mask airway insertion in children: effect of premedication with midazolam[J]. Br J Anaesth, 1996, 76(2): 308-309.
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