Application of Single-dose Contrast-enhanced Magnetic Resonance in Carotid Arteriography_West China Medical Journal

Authors：

HU Gang ¹ , XIA Chunchao ² ,  LI Zhenlin ² , CHEN Xian ²

1. Department of Radiology, General Hospital of Beijing Military Region, Beijing 100700, P. R. China; 2. Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, R. R. China;

Corresponding?author：

LI Zhenlin, Email: huyunke@sina.com

Keywords：

單倍劑量; 對比劑; 磁共振血管成像

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目的　探討常規注射速率下單倍劑量對比劑在頸部三維對比增強磁共振血管成像（3D-CEMRA）中的可行性及臨床應用價值。方法　2011年8月－11月，連續納入30例臨床懷疑頸動脈或椎動脈狹窄并要求頸部磁共振血管成像檢查的患者，隨機分成A、B兩組（每組各15例）。使用西門子Magnetom Avanto 1.5 T磁共振成像儀及其配備的頸部線圈和頭部線圈進行CEMRA成像。A組使用雙倍劑量對比劑（0.2 mmol/kg），B組使用單倍劑量對比劑（0.1 mmol/kg）。用三維快速小角度激發序列進行頸部血管成像。由2位有豐富經驗的高年資醫生對兩組原始圖像的信噪比以及最大密度投影（MIP）圖像的質量進行評價，并對結果進行統計學分析和處理。結果　A、B兩組的所頸動脈信噪比分別為189.95 ± 71.31、175.07 ± 68.61，差異無統計學意義（t=?0.566，P=0.576）；所得的MIP圖像質量均達到優良，差異無統計意義（χ2=0.180，P=0.671）。結論　與雙倍劑量相比，單倍劑量對比劑獲得頸部血管的圖像清晰，能夠滿足臨床診斷要求。

Citation： HU Gang,XIA Chunchao,LI Zhenlin,CHEN Xian. Application of Single-dose Contrast-enhanced Magnetic Resonance in Carotid Arteriography. West China Medical Journal, 2012, 27(6): 910-912. doi: Copy

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1. 　Leiner T. Magnetic resonance angiography of abdominal and lower extremity vasculature[J]. Top Magn Reson Imaging, 2005, 16(1): 21-66.
2. 　陸建平, 劉崎, 何新紅, 等. 三維對比劑增強MR血管成像對頸部動脈病變的診斷價值[J]. 中華放射學雜志, 2004, 38(1): 76-81.
3. 　Grobner T. Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?[J]. Nephrol Dial Transplant, 2006, 21(4): 1104-1108.
4. 　Prince MR, Zhang H, Morris M, et al. Incidence of nephrogenic systemic fibrosis at two large medical centers[J]. Radiology, 2008, 248(3): 807-816.
5. 　Heiserman JE, Dean BL, Hodak JA, et al. Neurologic complications of cerebral angiography[J]. Am J Neuroradiol, 1994, 15(8): 1401-1407.
6. 　Grzyska U, Freitag J, Zeumer H. Selective cerebral intraarteral DSA: complication rate and control of risk factors[J]. Neuroradiol, 1990, 32(1): 296-299.
7. 　Waugh JR, Sacharias N. Arteriographic complications in DSA era[J]. Radiology, 1992, 182(4): 243-246.
8. 　趙文海. MRA與DSA在頭頸部血管疾病中的診斷價值[J]. 中國醫療設備, 2010, 25(7): 100-102.
9. 　Michael B, France BM, Cornelis TP, et al. Accuracy of normal-dose contrast-enhanced MR angiography in assessing renal artery stenosis and accessory renal arteries[J]. AJR, 2000, 174(3): 629-634.
10. 　張云亭, 袁聿德. 醫學影像檢查技術[M]. 北京: 人民衛生出版社, 2005: 97-100.
11. 　曹麗珍, 李坤成, 杜祥穎, 等. 低劑量對比劑聯合生理鹽水在64層螺旋CT頭頸部血管成像中的應用[J]. 中華放射學雜志, 2007, 41(8): 821-824.
12. 　Timothy JC, Thomas MG. Technical developments in MR angiography[J]. Radiol Clin North Am, 2002, 40(4): 921-951.

West China Medical Journal

Application of Single-dose Contrast-enhanced Magnetic Resonance in Carotid Arteriography

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