Treatment of Facial Melasma with Intense Pulsed Light Photorejuvenation Combined with Vitamin C_West China Medical Journal

Authors：

ZHANG Lanfang , LEI Ying , LIU Hongyan

Department of Burn and Plastic Surgery, Nanchong Central Hospital, Nanchong, Sichuan 637000, P. R. China;

Corresponding?author：

Keywords：

光子嫩膚; 左旋維生素C; 黃褐斑

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【摘要】　目的　觀察光子嫩膚合并左旋維生素C導入治療面部黃褐斑的臨床療效。　方法　 2008年3月-2009年5月，105例黃褐斑患者隨機分為兩組，治療組53例，用光子嫩膚治療2個療程后用左旋維生素C導入，1次/周，持續2個月；對照組52例，單純使用光子嫩膚治療后進行防曬、護膚治療2個月。　結果　治療組有40例黃褐斑消失，13例色斑明顯減淡；對照組有12例黃褐斑消失，26例色斑明顯減淡，11例色斑減淡，3例無效。兩組療效比較，差異有統計學意義（P lt;0.05）。　結論　光子嫩膚合并左旋維生素C導入治療面部黃褐斑安全、方便、療效好，患者易于接受。
【Abstract】　Objective　 To observe the clinical efficacy of the treatment of facial melasma by intense pulsed light (IPL) photorejuvenation combined with vitamin C. 　Methods　 From March 2008 to May 2009, 105 patients with facial melasma were randomly divided into two groups. In the treatment group, there were 53 patients who were treated with vitamin C after IPL photorejuvenation once a week for two months. For the 52 patients in the control group, sunscreen and skin care treatment were carried out after IPL treatment for two months.　Results　 In the treatment group, 40 patients’ melasma disappeared and 13 patients’ melasma dodged obviously. In the control group, 12 patients’ melasma disappeared and pigmentation existed more or less in 40 patients.　Conclusion　 Treatment for facial melasma by IPL photorejuvenation combined with vitamin C is safe, convenient, and have good effect, which can be easily accepted by the patients.

Citation： ZHANG Lanfang,LEI Ying,LIU Hongyan. Treatment of Facial Melasma with Intense Pulsed Light Photorejuvenation Combined with Vitamin C. West China Medical Journal, 2011, 26(4): 544-546. doi: Copy

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9.	Wu X, Hammer JA. Making sense of melanosome dynamics in mouse melanocytes[J]. Pigment Cell Res, 2000, 13(4): 241-247.
10.	徐天華, 李遠宏, 祝霞, 等. 左旋維生素C美白、祛皺功效和安全性的臨床研究[J]. 中國美容醫學, 2009, 18(12): 1799.

1. 　歐陽恒, 楊志波. 顏面皮膚病中西醫結合診治[M]. 北京: 人民衛生出版社, 2003: 129-130.
2. 　沈大為. 四種霜劑治療黃褐斑[J]. 中國皮膚性病學雜志, 1994, 8(1): 54.
3. 　閆仲生, 王曉紅. 黃褐斑患者血清過氧化脂質及超氧化物歧化酶測定[J]. 臨床皮膚科雜志, 1994, 23(6): 351.
4. 　黃海濱, 梁建, 彭曉茹. 光子嫩膚技術治療面部黃褐斑的臨床觀察[J]. 中國實用美容整形外科雜志, 2006, 2(1): 10-11.
5. 　中國中西醫結合學會皮膚性病專業委員會色素病學組. 黃褐斑的臨床診斷和療效標準[J].中國中西醫結合皮膚性病學雜志, 2004, 3(1): 70.
6. 　Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation[J]. Science, 1983(4596), 220: 524-527.
7. 　高景恒, 白伶珉, 李孟倩. 強脈沖光在美容外科應用的文獻復習[J]. 實用美容整形外科雜志, 2003, 14(1): 39-42.
8. 　Lambert J, Vancoillie G, Naeyaert JM. Molecular motors and their role in pigmentation[J]. Cell Mol Biol, 1999, 45(7): 905-918.
9. 　Wu X, Hammer JA. Making sense of melanosome dynamics in mouse melanocytes[J]. Pigment Cell Res, 2000, 13(4): 241-247.
10. 　徐天華, 李遠宏, 祝霞, 等. 左旋維生素C美白、祛皺功效和安全性的臨床研究[J]. 中國美容醫學, 2009, 18(12): 1799.

West China Medical Journal

Treatment of Facial Melasma with Intense Pulsed Light Photorejuvenation Combined with Vitamin C

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