【摘要】　目的　 驗證臨床藥師對外科預防使用抗菌藥物進行干預的效果。　方法　 以臨床藥師督查記錄數據為基礎，將2010年1-3月238份病歷設為非干預組，2010年10—12月240份病歷設為干預組，建立評價標準，進行回顧性匯總、分析。　結果　 通過干預，抗菌藥物使用率從干預前的100%下降為77.08%（χ2=63.633，P=0.000），抗菌藥物聯用情況減少（χ2=53.712，P=0.000），用藥時機和用藥療程有了較大改善，抗菌藥物費用下降（t=-5.235，P=0.000），住院醫療費用降低（t’=-12.280，P=0.000），住院天數減少（t=-5.071，P=0.000）。　結論　 臨床藥師通過實施合理用藥干預對促進醫院安全、有效、經濟使用抗菌藥物起到了積極作用。
【Abstract】　Objective　 To verify the effect of clinical pharmacists’ intervention in antibiotics used for Type I incision surgical prevention.　Methods　 Based on the supervision and inspection recording data of clinical pharmacists, we arranged 238 medical records in the first quarter of 2010 as non-intervened group and 240 medical records in the fourth quarter of 2010 as intervened group, and then established evaluation criteria and conducted a retrospective study for analysis.　Results　 Through intervention, the rate of using antibiotics decreased from the previous 100% to 77.08% (χ2=63.633, P=0.000), the use of combined antibiotics also decreased (χ2=53.712, P=0.000), the time of course of using antibiotics improved, medical expenses of the antibiotics were reduced (t=-5.235, P=0.000), hospitalization cost decreased (t=-12.280, P=0.000), and hospital stay was shortened (t=-5.071, P=0.000).　Conclusion　 Clinical pharmacists’ intervention in rational use of drugs play a positive role in contribution to a safe, effective and economical application of antibiotics.

Citation： ZHENG Yongchi,CHEN Jia,YIN Jun. Analysis of the Effect of Clinical Pharmacists′ Intervention in Antibiotics Used for Type I Incision Surgical Prevention. West China Medical Journal, 2011, 26(6): 922-924. doi: Copy

Copyright ? the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved