Observation of the Curative Effect of Operation on Allergic Rhinitis by Laser Under Nasal Endoscope_West China Medical Journal

Authors：

ZHAO Rong ,  LIU Qiru

Department of Otorhinolaryngology, Chengdu Railway Center Hospital, Chengdu, Sichuan 610083, P. R. China;

Corresponding?author：

LIU Qiru, Email: lxrss@163.com

Keywords：

鼻內鏡; 激光治療; 變應性鼻炎

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【摘要】　目的　觀察鼻內鏡下激光治療變應性鼻炎的療效。　方法　 2005年6月－2008年7月采用鼻內鏡下Nd:YAG激光治療變應性鼻炎患者384例，其中男206例，女178例；年齡13~74歲，平均31歲。病程1~33年，平均7.7年。按照2004年制定的《變應性鼻炎診治原則及推薦方案》評分均 gt;6分。術前及術后1、6、24個月時分別對患者癥狀和體征進行評分和分析。　結果　所有患者均獲隨訪，隨訪時間1~24個月，平均22.7個月。其中術后1、6、24個月分別有384、380和358例患者獲隨訪。統計術前及術后1、6、24個月時癥狀以及體征評分總分分別為（11.32±1.03）、（3.06±1.17）、（3.32±1.37）、（4.09±2.03）分，術后各時間點評分均較術前顯著改善，差異有統計學意義（P lt;0.05）；術后各時間點間差異均有統計學意義（P lt;0.05），其中以術后1個月效果最好。　結論　鼻內鏡下激光治療變應性鼻炎療效確切，但遠期有一定復發率。
【Abstract】　Objective　 To explore the clinical efficacy of operation by laser under nasal endoscope for the treatment of allergic rhinitis.　Methods　 A total of 384 patients with allergic rhinitis undergoing operation by Nd : YAG laser under nasal endoscope from June 2005 to July 2008 were enrolled in the study, including 208 males and 178 females with their age ranged from 13 to 74 years old averaging at 31.2 years. The course of the disease ranged from 1 to 33 years averaging at 7.7 years. According to The Treatment Principle and Recommending Program for Allergic Rhinitis regulated in 2004, the scores of these cases were all higher than 6. Scoring and analysis of patients’ symptoms and body signs were performed before operation and 1, 6, and 24 months after operation.　Results　 All the patients were followed up with the time period ranged from 1 to 24 months averaging at 22.7 months. A total of 384, 380 and 358 patients were followed up respectively 1, 6, and 24 months after operation. The general score of symptoms and body signs before operation, 1, 6, 24 months after operation were respectively 11.32±1.03, 3.06±1.17, 3.32±1.37, and 4.09±2.03. The scores after operation were significantly better than that before operation (P lt;0.05). The curative effect at the first month was the best.　Conclusion　 Operation by laser under nasal endoscope is one of the valid, feasible methods for the treatment of allergic rhinitis, but during the long-term period, recurrence in some cases is possible.

Citation： ZHAO Rong,LIU Qiru. Observation of the Curative Effect of Operation on Allergic Rhinitis by Laser Under Nasal Endoscope. West China Medical Journal, 2011, 26(8): 1186-1188. doi: Copy

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1. 　顧之燕, 董震. 變應性鼻炎的診治原則和推薦方案(2004年, 蘭州)[J]. 中華耳鼻咽喉科雜志, 2005, 40(3): 166-167.
2. 　Casale TB, Dykewicz MS. Clinical implications of the allergic rhinitis-asthma link[J]. Am J Med Sci, 2004, 327(3): 127-138.
3. 　Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA)2008 update (in collaboration with the World Health Organization, GA(2) LEN and AllerGen)[J]. Allergy, 2008, 63 (Suppl 86): 8-160.
4. 　王正敏. 耳鼻喉科學新理論與新技術[M]. 上海: 上海科學技術出版社, 1997: 114-116.
5. 　左冬至, 耿宛平, 劉強和. 變應性鼻炎治療的進展[J]. 中國耳鼻咽喉顱底外科雜志, 2010, 16(2): 157-160.
6. 　Calamita Z, Saconato H, Pelá AB, et al. Efficacy of sublingual immunotherapy in asthma: systematic review of randomized-clinical trials using the Cochrane Collaboration method[J].Allergy, 2006, 61(10): 1162-1172.
7. 　Hol MK, Huizing EH. Treatment of inferior turbinatepathololgy: a review and critical evaluation of the different techniques[J]. Rhinology, 2000, 38(4): 157-166.
8. 　仇榮星, 顧凌瀾. 兩種激光治療常年性變應性鼻炎的療效對比[J]. 中國耳鼻咽喉顱底外科雜志, 2010, 16(1): 63-64.
9. 　朱菁. 激光醫學[M]. 上海: 上海科學技術出版社, 2003: 505.
10. 　田廣永, 劉長秀. 鼻中隔矯正手術中下鼻甲的處理[J]. 中國耳鼻咽喉顱底外科雜志, 2006, 12(5): 52-56.
11. 　曾強, 楊濱, 盧永德, 等. 鼻內窺鏡下Nd-YAG激光治療常年性鼻炎[J]. 中國耳鼻咽喉顱底外科雜志, 1997, 3(3): 190.

West China Medical Journal

Observation of the Curative Effect of Operation on Allergic Rhinitis by Laser Under Nasal Endoscope

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