Application of Early Oral Feeding after Curative Surgery for Distal Gastric Cancer_West China Medical Journal

Authors：

LIU Bin ¹ , CHEN Jinhui ¹ , HUANG Shifeng ²

1. Department of General Surgery, the Eighth Hospital of Changsha, Changsha, Hunan 410100, P. R. China; 2. Department of General Surgery, the Fourth Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi 545005, P. R. China;

Corresponding?author：

Keywords：

早期進食; 胃癌; 胃腸功能

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

【摘要】　目的　探討遠端胃癌根治術后早期經口進食的可行性、安全性及術后早期康復情況。　方法　將2009年5月-2011年1月收治的62例遠端胃癌根治術患者隨機分為早期經口進食（early oral feeding，EOF，30例）組及傳統進食（traditional feeding，TF，32例）組。比較兩種營養支持方法對患者術后并發癥、胃腸功能恢復及血清蛋白的影響。　結果　 EOF組術后早期經口進食耐受率達90%（27/30），兩組術后并發癥發生率相比差異無統計學意義（χ2=0.046，P=0.830）。EOF組術后首次肛門排氣及排便時間均早于TF組（P=0.000）。術后8 d時EOF組血清前清蛋白和轉鐵蛋白明顯高于TF組（P=0.028，0.013）。　結論　遠端胃癌根治術后早期經口進食是安全、可行的，能促進患者的早期恢復。
【Abstract】　Objective　 To discuss the feasibility and safety of early oral feeding after curative surgery for distant gastric cancer, and investigate whether it has an effect on early recovery of the disease.　Methods　 From May 2009 to January 2011, 62 distal gastric cancer patients with open radical resection were divided into the early oral feeding group (EOF group, n=30) and traditional feeding group (TF group, n=32) randomly. We compared the complication rate, gastrointestinal function recovery, serum protein change before and after operation between the two groups.　Results　 Early oral feeding can be tolerated by as much as 90% (27/30) of the patients in EOF group. There was no significant difference in the postoperative complication rate between the two groups (χ2=0.046, P=0.830). The EOF group had a faster onset of flatus and defecation than the TF group (P=0.000). The serum pre-albumin and transferrin were significantly higher in the EOF group than those in the TF group 8 days after operation (P=0.028,0.013).　Conclusion　 Early oral feeding after curative surgery for distal gastric cancer is safe and feasible, and can promote early rehabilitation of the patients.

Citation： LIU Bin,CHEN Jinhui,HUANG Shifeng. Application of Early Oral Feeding after Curative Surgery for Distal Gastric Cancer. West China Medical Journal, 2011, 26(11): 1666-1668. doi: Copy

1.	Kang WM, Yu JC, Zhang Q, et al. Effects of enteral and parenteral nutrition on gastroenteric hormones and gastric motility after subtotal gastrectomy[J]. Chin Med Sci J, 2008, 23(2): 113-116.
2.	陳平, 丁國平, 鄭祺, 等. 快速康復外科理念在胃癌圍手術期中的應用[J]. 中國普通外科雜志, 2010, 19(6): 669-572.
3.	李卡, 蔣理立, 黃曉. 結直腸癌術后早期腸內營養對胃腸功能恢復的影響[J]. 華西醫學, 2010, 25(1): 216-217.
4.	Gianotti L, Nespoli L, Torselli L, et al. Safety, feasibility, and tolerance of early oral feeding after colorectal resection outside an enhanced recovery after surgery (ERAS) program[J]. Int J Colorectal Dis, 2011, 26(6): 747-753.
5.	Serafini F, Anderson W, Ghassemi P, et al. The utility of contrast studies and drains in the management of patients after Roux-en-Y gastric bypass[J]. Obes Surg, 2002, 12(1): 34-38.
6.	胡芳, 田偉軍, 梁曉宇, 等. 代謝車監測靜息能量消耗對腹部外科患者營養支持的意義[J]. 天津醫科大學學報, 2005, 11(3): 399-400.
7.	廖有祥, 湯恢煥, 劉慶武, 等. 胃癌手術后胃癱綜合征的多因素分析[J]. 中國普通外科雜志, 2008, 17(4): 318-321.
8.	王軍武, 武曉汀. 腹部針刺治療早期炎性腸梗阻65例[J]. 華西醫學, 2008, 23(2): 238.
9.	Baskin WN. Advances in enteral nutrition techniques[J]. Am J Gastroenterol, 1992, 87(11): 1547-1553.
10.	Counihan TC, Favuzza J. Fast track colorectal surgery[J]. Clin Colon Rectal Surg, 2009, 22(1): 60-72.
11.	Fukuzawa J, Terashima H, Ohkohchi N. Early postoperative oral feeding accelerates upper gastrointestinal anastomotic healing in the rat model[J]. World J Surg, 2007, 31(6): 1234-1239.
12.	Hur H, Si Y, Kang WK, et al. Effects of early oral feeding on surgical outcomes and recovery after curative surgery for gastric cancer: pilot study results[J]. World J Surg, 2009, 33(7): 1454-1458.
13.	Hur H, Kim SG, Shim JH, et al. Effect of early oral feeding after gastric cancer surgery: a result of randomized clinical trial[J]. Surgery, 2011, 149(4): 561-568.

1. 　Kang WM, Yu JC, Zhang Q, et al. Effects of enteral and parenteral nutrition on gastroenteric hormones and gastric motility after subtotal gastrectomy[J]. Chin Med Sci J, 2008, 23(2): 113-116.
2. 　陳平, 丁國平, 鄭祺, 等. 快速康復外科理念在胃癌圍手術期中的應用[J]. 中國普通外科雜志, 2010, 19(6): 669-572.
3. 　李卡, 蔣理立, 黃曉. 結直腸癌術后早期腸內營養對胃腸功能恢復的影響[J]. 華西醫學, 2010, 25(1): 216-217.
4. 　Gianotti L, Nespoli L, Torselli L, et al. Safety, feasibility, and tolerance of early oral feeding after colorectal resection outside an enhanced recovery after surgery (ERAS) program[J]. Int J Colorectal Dis, 2011, 26(6): 747-753.
5. 　Serafini F, Anderson W, Ghassemi P, et al. The utility of contrast studies and drains in the management of patients after Roux-en-Y gastric bypass[J]. Obes Surg, 2002, 12(1): 34-38.
6. 　胡芳, 田偉軍, 梁曉宇, 等. 代謝車監測靜息能量消耗對腹部外科患者營養支持的意義[J]. 天津醫科大學學報, 2005, 11(3): 399-400.
7. 　廖有祥, 湯恢煥, 劉慶武, 等. 胃癌手術后胃癱綜合征的多因素分析[J]. 中國普通外科雜志, 2008, 17(4): 318-321.
8. 　王軍武, 武曉汀. 腹部針刺治療早期炎性腸梗阻65例[J]. 華西醫學, 2008, 23(2): 238.
9. 　Baskin WN. Advances in enteral nutrition techniques[J]. Am J Gastroenterol, 1992, 87(11): 1547-1553.
10. 　Counihan TC, Favuzza J. Fast track colorectal surgery[J]. Clin Colon Rectal Surg, 2009, 22(1): 60-72.
11. 　Fukuzawa J, Terashima H, Ohkohchi N. Early postoperative oral feeding accelerates upper gastrointestinal anastomotic healing in the rat model[J]. World J Surg, 2007, 31(6): 1234-1239.
12. 　Hur H, Si Y, Kang WK, et al. Effects of early oral feeding on surgical outcomes and recovery after curative surgery for gastric cancer: pilot study results[J]. World J Surg, 2009, 33(7): 1454-1458.
13. 　Hur H, Kim SG, Shim JH, et al. Effect of early oral feeding after gastric cancer surgery: a result of randomized clinical trial[J]. Surgery, 2011, 149(4): 561-568.

West China Medical Journal

Application of Early Oral Feeding after Curative Surgery for Distal Gastric Cancer

Abstract Full text Figures/Tables Video References Cited by

Format

Content