Clinical Observation of Homemade Platelet-Rich Plasma on Refractory Wound_West China Medical Journal

Authors：

ZHAO Qiang , TAN Xianchun , CHEN Xingai , LIN Daqiang

Department of Orthopedics, The Second People’s Hospital of Dazhou, Dazhou, Sichuan 635000, P.R.China;

Corresponding?author：

Keywords：

富血小板血漿; 難治性創口; 臨床應用

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【摘要】目的 觀察自制富血小板血漿治療難治性創口的臨床療效。方法 2007年4月-2009年11月對38例難治性創口患者進行自制富血小板血漿治療，觀察創面愈合變化情況。結果 38例患者中30例愈合，2例顯效，2例有效，總有效率為90%。結論自制富血小板血漿治療難治性創口是一種簡便、安全、價廉、有效的治療方式，特別適合中小（25~60 cm2）創面的難治性創口。
【Abstract】 Objective To observe the clinical effect of homemade platelet-rich plasma on refractory wound. Methods Thirty-eight patients with refractory wound from April 2007 to November 2009 were treated by homemade platelet-rich plasma, and the changes in wound healing were observed. Results Thirty patients were healed, two patients were markedly effective, two patients were effective and the total effective rate was 90%. Conclusion Homemade platelet-rich plasma is a simple, safe, inexpensive and effective treatment on refractory wound, especially for small and medium refractory wounds (25-60 cm2).

Citation： ZHAO Qiang,TAN Xianchun,CHEN Xingai,LIN Daqiang. Clinical Observation of Homemade Platelet-Rich Plasma on Refractory Wound. West China Medical Journal, 2010, 25(8): 1457-1458. doi: Copy

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1. 付小兵, 程飚, 盛志勇．生長因子應用于臨床創傷修復——十年的主要進展與展望[J].中國修復重建外科雜志, 2004, 18(6): 508-512.
2. 袁霆, 張長青. 骨組織與軟組織修復作用中富血小板血漿的制作及其原理[J]. 中國臨床康復, 2004, 8(35): 7939-7941 .
3. 朱旭東, 王正國, 張艷, 等. 血小板源性愈合因子改善糖尿病大鼠傷口愈合及與轉化生長因子表達的相關性[J]. 中華創傷雜志, 2000, 16(11): 678-680.
4. Carter CA, Jolly DG, Worden CE Sr, et al. Platelet-rich plasma gel promotes differentiation and regeneration during equine wound healing[J]. Exp Mol Pathol, 2003, 74(3): 244-255.
5. Tsubone T, Mora SL, Amadio PC, et al. Expression of growth factors in canine after laceration in[J]. Plast Surg, 2004, 53(4): 393-397.
6. Wernr S, Grose R. Regulation of wound healing by growth factors and cytokines[J]. Physiol Rev, 2003, 83(10): 835-870.

West China Medical Journal

Clinical Observation of Homemade Platelet-Rich Plasma on Refractory Wound

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