【摘要】 目的  探討頑固性癲癇外科術前與術中癲癇病灶定位的異同及手術方式的選擇。 方法  2002年7月-2009年10月收治復雜、部分發作的頑固性癲癇78例。術前癲癇病灶定位主要采用頭MRI及24 h視頻腦電圖檢查，癲癇病灶局限于顳葉31例，顳葉、額葉47例。術中行24導皮層腦電圖監測進一步定位癲癇病灶，并在其指導下聯合多種癲癇術式完成手術。 結果  術前視頻腦電圖檢查定位癲癇病灶與術中皮層腦電圖監測定位具有高度一致性，但后者定位范圍較前者有擴大。 結論  術中皮層腦電圖監測證實并進一步精確定位癲癇病灶范圍，以及在指導手術切除癲癇病灶范圍，癲癇術式選擇方面具有重要意義。
【Abstract】 Objective  To evaluate the preoperative and intraoperative epileptogenic focus location variation, and indication of surgical options for elevating outcome of refractory epilepsy patitents. Methods  All of 78 refractory epilepsy patitents were complex partial seizure. Magnetic resonance imaging and 24 hour video electroencephalogram (VEEG) were used to orientate epileptogenic focus preoperatively. Thirty-one patiens were limited to temporal and forty-seven patients were both temporal and frontal. Twenty-four lead electrocorticogram (ECoG) was used to orientate epileptogenic focus intraoperatively and directed multiple operative patterns. Results  Thereisa certain coherence between Preoperative VEEG and intraoperative ECoG epileptogenic focus location, but larger rangein latter. Conclusion  Intraoperative e ECoG may orientate epileptogenic focus further accurately, for the suitable surgical options and appropriate surgical excision.

Citation： GAO Limin,GAO Jinjian,ZHAO Hexiang,FENG Wen,ZHANG Wenzhao. Comparsion of Electrocorticogram and Video Electroencephalogram Effectiveness for Surgical Treatment of Refractory Epilepsy. West China Medical Journal, 2010, 25(9): 1641-1643. doi: Copy

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