目的：研究影響機械通氣患者BIS值的相關因素。方法：42例機械通氣患者，BIS模塊連續監測鎮靜深度48小時，記錄患者鎮靜前后、每隔16小時的呼吸循環指標，BIS值、SAS評分，建立混合線形統計模型，評價BIS監測的影響因素。結果：患者的血壓、心率、呼吸頻率、PaO2、SPO2 、FiO2等均對BIS值無影響，僅有PaCO2和SAS評分與BIS相關(P＜0.05)。結論：BIS模塊監測機械通氣患者鎮靜深度，BIS值的變化與患者PaCO2及SAS評分有關。
Citation：
LI Xiaojin,ZHANG Chuan,ZHENG Bixia,et al. The Research of Related Factors in Affecting the Bispectral Index Monitoring for the Depth of Sedation of Ventilated Patients. West China Medical Journal, 2009, 24(2): 362-363. doi:
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- 1. Brocas，E，Dupont，H，Paugam Burtz C.Bispectral index variations during tracheal suction in mechanically ventilated critically ill patients：effect of an alfentanil bolus[J].Intensive Care Med，2002，28(2)：211-213..
- 2. Ball J.How useful is the bispectral index in the management of ICU patients?[J]Minerva Anestesiol，2002，68(4)：248-251..
- 3. Simmons L E，Riker R R，Prato B S，et al.Assessing sedation during intensive care unit mechanical ventilation with the Bispectral Index and the SedationAgitation Scale[J].Crit Care Med，1999，27(8)：1499-1504..
- 4. Mondello E，Siliotti R，Noto G，et al.Bispectral Index in ICU：correlation with Ramsay Score on assessment of sedation level[J].J Clin Monit Comput，2002，17(5)：271-277..
- 5. Riker R R，Fraser G L，Simmons L E，et al.Validating the SedationAgitation Scale with the Bispectral Index and Visual Analog Scale in adult ICU patients after cardiac surgery[J].Intensive Care Med，2001，27(5)：853-858..
- 6. 張川，李孝錦，李曉玉，等.BIS監測對診斷機械通氣患者鎮靜深度的價值[J].華西醫學，2008，23，(1)：41-42..
- 7. Medicis JJ，Hu A，Lopez C，et al.Comparsion of standard sedation assessment to bispectral analysis in patients who are on neuromuscular blockers：A pilot study[C].ASHP Midyear Clinical Meeting(ASHP Midyear Clinical Meeting)，2002，37(DEC)：P-347R..
