目的:探討激素及免疫抑制劑導致乙肝病毒再激活所致的肝損害的危害性及治療效果，指導臨床治療。方法：總結本院近2年收治的7例慢性乙肝病毒感染者在使用激素及免疫抑制劑致肝炎再激活并加重患者的臨床資料進行分析。結果：慢性乙肝病毒感染者因各種原因使用激素及免疫抑制劑所導致的慢性乙肝的復發加重，病情發展迅速，病死率高。結論：抗乙肝病毒治療是預防肝病復發并惡化的關鍵，在激素或免疫抑制劑治療前和治療中都應使乙肝病毒降至盡可能低的水平。
Citation：
RAN Jing,FENG Ping. Clinical Analysis of 7 Cases with Chronic Hepatitis B Relapse and Exacerbations Caused by Corticosteroids and Immunosuppressant Reactivation. West China Medical Journal, 2009, 24(2): 419-421. doi:
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| 1. |
|
| 2. |
Rossi G，Pelizzari A，Motta M，et al.Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy[J].Br J Haematol，2001，115(1)：58-62..
|
| 3. |
Brid AM，Bennett MK，Bassenine MF，et al.Nucleoside analogue therapy in fibrosing cholestatic hepatitis：a case report in an HBsAg postive renal transplant recipient[J].Liver，1998，18(2)：134-139..
|
| 4. |
Benner KG，Loe RG，Keeffe EB，et al.Fibrosing cytolytic liver failure secondary to recurrent hepatitis B after livertransplantation[J].Gastroenterology，1992，103(4)：1307-1312..
|
| 5. |
Lee WC，Wu MJ，Cheng CH，et al.Lamivudine is effective for the treatment of reactivation of hepatitis B virus and fulminant hepatic failure in renal transplant recipients[J].Am J Kidney Dis，2001，38(5)：1074-81..
|
| 6. |
中華醫學會感染病學分會、肝病學分會.慢性乙型肝炎防治指南[S].肝臟，2005，10(4)：348-357..
|
- 1.
- 2. Rossi G，Pelizzari A，Motta M，et al.Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy[J].Br J Haematol，2001，115(1)：58-62..
- 3. Brid AM，Bennett MK，Bassenine MF，et al.Nucleoside analogue therapy in fibrosing cholestatic hepatitis：a case report in an HBsAg postive renal transplant recipient[J].Liver，1998，18(2)：134-139..
- 4. Benner KG，Loe RG，Keeffe EB，et al.Fibrosing cytolytic liver failure secondary to recurrent hepatitis B after livertransplantation[J].Gastroenterology，1992，103(4)：1307-1312..
- 5. Lee WC，Wu MJ，Cheng CH，et al.Lamivudine is effective for the treatment of reactivation of hepatitis B virus and fulminant hepatic failure in renal transplant recipients[J].Am J Kidney Dis，2001，38(5)：1074-81..
- 6. 中華醫學會感染病學分會、肝病學分會.慢性乙型肝炎防治指南[S].肝臟，2005，10(4)：348-357..
