Analysis of Complication of Right Lobe Donors of Adult to Adult Living Donor Liver Transplantation_West China Medical Journal

Authors：

YANG Bairen , YANG Jiayin , YAN Lvnan , et al.

Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding?author：

Keywords：

肝移植; 手術后; 并發癥; 安全性

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目的:探討活體右半肝移植供體術后并發癥及其處理。方法:回顧性分析了我院肝移植中心的120例活體肝移植供體術后并發癥發生的類型和臨床處理方法。結果:120例活體肝移植供體術后都出現肝功能實驗室指標的短期變化,其中114例術后1周內恢復正常;6例恢復時間大于1周。術后并發癥總發生率9.16%,其中嚴重并發癥發生率4.16%,輕微并發癥發生率5.00%。所有術后并發癥得到及時的發現和處理,恢復良好。結論:經過嚴密的術前檢查和評估、充分的術前準備、細致的術中操作和全面的術后監護與治療,活體右半肝移植供體的手術安全性較高,近期預后較好。

Citation： YANG Bairen,YANG Jiayin,YAN Lvnan,et al.. Analysis of Complication of Right Lobe Donors of Adult to Adult Living Donor Liver Transplantation. West China Medical Journal, 2009, 24(6): 1371-1374. doi: Copy

1.	CHOI S J, GWAK M S, KIM M H, et al. Differences of perioperative liver function, transfusion, and complications according to the type of hepatectomy in living donors[J]. Transplant International,2005,18(5):548-55..
2.	TROTTER J F, ADAM R, LO C M, et al. Documented deaths of hepatic lobe donors for living donor liver transplantation[J]. Liver Transplantation,2006,12(10):1485-1488.
3.	BEAVERS K L, SANDLER R S, SHRESTHA R. Donor morbidity associated with right lobectomy for living donor liver transplantation to adult recipients: a systematic review[J]. Liver Transplantation,2002,8(2):110-117.
4.	GHOBRIAL R M, FREISE C E, TROTTER J F, et al. Donor morbidity after living donation for liver transplantation[J]. Gastroenterology,2008,135(2):468-476.
5.	文天夫,嚴律南,李波,等.活體右半肝供體的安全性[J].中華外科雜志,2006,44(3):149.
6.	MARSMAN W A, WIESNER R H, RODRIGUEZ L, et al. Use of fatty liver is associated with diminished early patient and graft survival[J]. Transplantation,1996,62:1246-1251.
7.	RINELLA M E, ALONSO E, RAO S, et al. Body mass index as a predictor of hepatic steatosis in living liver donors[J]. Liver Transplantation,2001,7:409-414.
8.	BROWN R S JR, RUSSO M W, LAI M, et al. A survey of liver transplantation from living adult donors in the United States[J]. N Engl J Med,2003,348:818-825.
9.	Umeshita K, Fujiwara K, Kiyosawa K, et al. Operative morbidity of living liver donors in Japan[J]. Lancet,2003,362:687–690.
10.	LEE S G, PARK K M, HWANG S, et al. Adulttoadult living donor liver transplantation at the Asan Medical Center Korea[J]. Asian J Surg,2002,25:277-284.
11.	LO C M. Complications and longterm outcome of living liver donors: a survey of 1,508 cases in five Asian centers[J]. Transplantation,2003,75(3 Suppl):S12-15.
12.	ITO T, KIUCHI T, EGAWA H, et al. Surgeryrelated morbidity in living donors of rightlobe liver graft: lessons from the first 200 cases[J]. Transplantation,2003,76(1):158-163.
13.	SHIO S, YAZUMI S, OGAWA K, et al. Biliary complications in donors for living donor liver transplantation[J]. Am J Gastroenterol,2008,103(6):1393-1398.
14.	TROTTER J F, HILLCALLAHAN M M, GILLESPIE B W, et al. Severe psychiatric problems in right hepatic lobe donors for living donor liver transplantation[J]. Case Reports. Transplantation,2007,83(11):1506-1508.

1. CHOI S J, GWAK M S, KIM M H, et al. Differences of perioperative liver function, transfusion, and complications according to the type of hepatectomy in living donors[J]. Transplant International,2005,18(5):548-55..
2. TROTTER J F, ADAM R, LO C M, et al. Documented deaths of hepatic lobe donors for living donor liver transplantation[J]. Liver Transplantation,2006,12(10):1485-1488.
3. BEAVERS K L, SANDLER R S, SHRESTHA R. Donor morbidity associated with right lobectomy for living donor liver transplantation to adult recipients: a systematic review[J]. Liver Transplantation,2002,8(2):110-117.
4. GHOBRIAL R M, FREISE C E, TROTTER J F, et al. Donor morbidity after living donation for liver transplantation[J]. Gastroenterology,2008,135(2):468-476.
5. 文天夫,嚴律南,李波,等.活體右半肝供體的安全性[J].中華外科雜志,2006,44(3):149.
6. MARSMAN W A, WIESNER R H, RODRIGUEZ L, et al. Use of fatty liver is associated with diminished early patient and graft survival[J]. Transplantation,1996,62:1246-1251.
7. RINELLA M E, ALONSO E, RAO S, et al. Body mass index as a predictor of hepatic steatosis in living liver donors[J]. Liver Transplantation,2001,7:409-414.
8. BROWN R S JR, RUSSO M W, LAI M, et al. A survey of liver transplantation from living adult donors in the United States[J]. N Engl J Med,2003,348:818-825.
9. Umeshita K, Fujiwara K, Kiyosawa K, et al. Operative morbidity of living liver donors in Japan[J]. Lancet,2003,362:687–690.
10. LEE S G, PARK K M, HWANG S, et al. Adulttoadult living donor liver transplantation at the Asan Medical Center Korea[J]. Asian J Surg,2002,25:277-284.
11. LO C M. Complications and longterm outcome of living liver donors: a survey of 1,508 cases in five Asian centers[J]. Transplantation,2003,75(3 Suppl):S12-15.
12. ITO T, KIUCHI T, EGAWA H, et al. Surgeryrelated morbidity in living donors of rightlobe liver graft: lessons from the first 200 cases[J]. Transplantation,2003,76(1):158-163.
13. SHIO S, YAZUMI S, OGAWA K, et al. Biliary complications in donors for living donor liver transplantation[J]. Am J Gastroenterol,2008,103(6):1393-1398.
14. TROTTER J F, HILLCALLAHAN M M, GILLESPIE B W, et al. Severe psychiatric problems in right hepatic lobe donors for living donor liver transplantation[J]. Case Reports. Transplantation,2007,83(11):1506-1508.

West China Medical Journal

Analysis of Complication of Right Lobe Donors of Adult to Adult Living Donor Liver Transplantation

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