Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation_West China Medical Journal

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Science City Hospital, Mianyang Sichuan 621900, China;

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Keywords：

血管緊張素Ⅱ受體拮抗劑; 陣發性AF; P波離散度

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目的:探討血管緊張素Ⅱ受體拮抗劑(ARB)對PAF患者P波離散度的影響。方法:觀察48 例陣發性AF患者的最寬P 波和P 波離散度,并與ARB干預治療3 個月后進行對比分析。結果:ARB治療3個月后最寬P波、P 波離散度及P 波離散度≥40 ms的例數與治療前比較差異有統計學意義 (P lt;0.05或 lt;0.01)。結論:ARB能減輕PAF患者心房結構重構及電重構,減少AF的發生。

Citation： ZHAO Guozhong,CHEN Chen,FENG Xiaolan,et al.. Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation. West China Medical Journal, 2009, 24(6): 1445-1446. doi: Copy

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1.
2. 郝亞榮,吳剛,黃從新,等. P波離散度對特發性陣發性心房顫動的預測價值[J]. 中國心臟起搏與心電生理雜志,2001,15 (3):199-121.
3. 郭繼鴻.新概念心電圖[M].第3版.北京大學醫學出版社,2007:122-127.
4. 劉艷秋, 張振剛, 龔開政, 等. P 波變化、左房內徑及左室舒張功能與冠心病陣發性心房顫動的關系[J]. 實用臨床醫藥雜志, 2004, 8 (5) ∶108.
5. WRIGHT JW,HARDING JW. Brain agiotensin receptor subtypes AT and their functions[J]. Regul Rept,1995,59:269.
6. LOPEZ B, QUEREJETA R, VARO N, et al. Usefulness of serum carboxy terminal propep tide of procollagen type I in assessment of the cardio reparative ability of antihypertensive treatment in hypertensive patients[J]. Circulation, 2001, 104(2) ∶286.
7. NAKASHIMA H, KUMAGAI K, URATA H, et al. Angiotensin Ⅱ antagonist prevents electrical remodeling in atrial fibrillation[J]. Circulat ion, 2000, 101 (6) ∶2612.
8. KIM S,LWAO H. Molecular and cellular meehallisms of angiotensin Ⅱmediated cardiovascular and renal diseases[J]. Pharmacol Rev, 2000, 52:11-34.

West China Medical Journal

Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation

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